BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

245 related articles for article (PubMed ID: 37295550)

  • 1. The YEATS domain epigenetic reader proteins ENL and AF9 and their therapeutic value in leukemia.
    Hu H; Muntean AG
    Exp Hematol; 2023 Aug; 124():15-21. PubMed ID: 37295550
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The ENL YEATS epigenetic reader domain critically links MLL-ENL to leukemic stem cell frequency in t(11;19) Leukemia.
    Hu H; Saha N; Yang Y; Ahmad E; Lachowski L; Shrestha U; Premkumar V; Ropa J; Chen L; Teahan B; Grigsby S; Marschalek R; Nikolovska-Coleska Z; Muntean AG
    Leukemia; 2023 Jan; 37(1):190-201. PubMed ID: 36435883
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Intrinsically Disordered Proteins MLLT3 (AF9) and MLLT1 (ENL) - Multimodal Transcriptional Switches With Roles in Normal Hematopoiesis, MLL Fusion Leukemia, and Kidney Cancer.
    Kabra A; Bushweller J
    J Mol Biol; 2022 Jan; 434(1):167117. PubMed ID: 34174329
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural studies of intrinsically disordered MLL-fusion protein AF9 in complex with peptidomimetic inhibitors.
    Yang Y; Ahmad E; Premkumar V; Liu A; Ashikur Rahman SM; Nikolovska-Coleska Z
    Protein Sci; 2024 Jun; 33(6):e5019. PubMed ID: 38747396
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Targeting recruitment of disruptor of telomeric silencing 1-like (DOT1L): characterizing the interactions between DOT1L and mixed lineage leukemia (MLL) fusion proteins.
    Shen C; Jo SY; Liao C; Hess JL; Nikolovska-Coleska Z
    J Biol Chem; 2013 Oct; 288(42):30585-30596. PubMed ID: 23996074
    [TBL] [Abstract][Full Text] [Related]  

  • 6. SIRT2 regulates proliferation and chemotherapy response of MLL-ENL-driven acute myeloid leukemia.
    Hao C; Shao X; Song J; Peng M; Lao Y; Mack R; Zhang L; Wei W; Liu N; Wang T; Wu Y; Feng L; Yin L; Wang S; Sun X; Chen S; Zhang J; Li B
    Biochem Biophys Res Commun; 2022 Mar; 596():36-42. PubMed ID: 35108652
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Discovery of a Selective Inhibitor for the YEATS Domains of ENL/AF9.
    Christott T; Bennett J; Coxon C; Monteiro O; Giroud C; Beke V; Felce SL; Gamble V; Gileadi C; Poda G; Al-Awar R; Farnie G; Fedorov O
    SLAS Discov; 2019 Feb; 24(2):133-141. PubMed ID: 30359161
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Transcription control by the ENL YEATS domain in acute leukaemia.
    Erb MA; Scott TG; Li BE; Xie H; Paulk J; Seo HS; Souza A; Roberts JM; Dastjerdi S; Buckley DL; Sanjana NE; Shalem O; Nabet B; Zeid R; Offei-Addo NK; Dhe-Paganon S; Zhang F; Orkin SH; Winter GE; Bradner JE
    Nature; 2017 Mar; 543(7644):270-274. PubMed ID: 28241139
    [TBL] [Abstract][Full Text] [Related]  

  • 9. ZNF521 Enhances MLL-AF9-Dependent Hematopoietic Stem Cell Transformation in Acute Myeloid Leukemias by Altering the Gene Expression Landscape.
    Chiarella E; Aloisio A; Scicchitano S; Todoerti K; Cosentino EG; Lico D; Neri A; Amodio N; Bond HM; Mesuraca M
    Int J Mol Sci; 2021 Oct; 22(19):. PubMed ID: 34639154
    [TBL] [Abstract][Full Text] [Related]  

  • 10. EVI1 is critical for the pathogenesis of a subset of MLL-AF9-rearranged AMLs.
    Bindels EM; Havermans M; Lugthart S; Erpelinck C; Wocjtowicz E; Krivtsov AV; Rombouts E; Armstrong SA; Taskesen E; Haanstra JR; Beverloo HB; Döhner H; Hudson WA; Kersey JH; Delwel R; Kumar AR
    Blood; 2012 Jun; 119(24):5838-49. PubMed ID: 22553314
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Learning from mouse models of MLL fusion gene-driven acute leukemia.
    Schwaller J
    Biochim Biophys Acta Gene Regul Mech; 2020 Aug; 1863(8):194550. PubMed ID: 32320749
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Collaboration of MLLT1/ENL, Polycomb and ATM for transcription and genome integrity.
    Ui A; Yasui A
    Nucleus; 2016 Apr; 7(2):138-45. PubMed ID: 27310306
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Small-molecule inhibitor of AF9/ENL-DOT1L/AF4/AFF4 interactions suppresses malignant gene expression and tumor growth.
    Wu F; Nie S; Yao Y; Huo T; Li X; Wu X; Zhao J; Lin YL; Zhang Y; Mo Q; Song Y
    Theranostics; 2021; 11(17):8172-8184. PubMed ID: 34373735
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Fragment-Based Discovery of AF9 YEATS Domain Inhibitors.
    Liu Y; Jin R; Lu H; Bian K; Wang R; Wang L; Gao R; Zhang J; Wu J; Yao X; Liu X; Liu D; Wang X; Zhang Z; Ruan K
    Int J Mol Sci; 2022 Mar; 23(7):. PubMed ID: 35409252
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Bahcc1 is critical for the aberrant epigenetic program in a mouse model of MLL-ENL-mediated leukemia.
    Nakamura A; Masuya M; Shinmei M; Tawara I; Nosaka T; Ono R
    Blood Adv; 2024 May; 8(9):2193-2206. PubMed ID: 38452334
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Human Polymerase-Associated Factor complex (PAFc) connects the Super Elongation Complex (SEC) to RNA polymerase II on chromatin.
    He N; Chan CK; Sobhian B; Chou S; Xue Y; Liu M; Alber T; Benkirane M; Zhou Q
    Proc Natl Acad Sci U S A; 2011 Sep; 108(36):E636-45. PubMed ID: 21873227
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Tip60 activates Hoxa9 and Meis1 expression through acetylation of H2A.Z, promoting MLL-AF10 and MLL-ENL acute myeloid leukemia.
    Yamagata K; Shino M; Aikawa Y; Fujita S; Kitabayashi I
    Leukemia; 2021 Oct; 35(10):2840-2853. PubMed ID: 33967269
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Function of leukemogenic mixed lineage leukemia 1 (MLL) fusion proteins through distinct partner protein complexes.
    Biswas D; Milne TA; Basrur V; Kim J; Elenitoba-Johnson KS; Allis CD; Roeder RG
    Proc Natl Acad Sci U S A; 2011 Sep; 108(38):15751-6. PubMed ID: 21896721
    [TBL] [Abstract][Full Text] [Related]  

  • 19. MLL-AF9 and MLL-ENL alter the dynamic association of transcriptional regulators with genes critical for leukemia.
    Monroe SC; Jo SY; Sanders DS; Basrur V; Elenitoba-Johnson KS; Slany RK; Hess JL
    Exp Hematol; 2011 Jan; 39(1):77-86.e1-5. PubMed ID: 20854876
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Essential role of PR-domain protein MDS1-EVI1 in MLL-AF9 leukemia.
    Zhang Y; Owens K; Hatem L; Glass CH; Karuppaiah K; Camargo F; Perkins AS
    Blood; 2013 Oct; 122(16):2888-92. PubMed ID: 24021671
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.