172 related articles for article (PubMed ID: 37296098)
1. Substrate binding-induced conformational transitions in the omega-3 fatty acid transporter MFSD2A.
Bergman S; Cater RJ; Plante A; Mancia F; Khelashvili G
Nat Commun; 2023 Jun; 14(1):3391. PubMed ID: 37296098
[TBL] [Abstract][Full Text] [Related]
2. Structural basis of omega-3 fatty acid transport across the blood-brain barrier.
Cater RJ; Chua GL; Erramilli SK; Keener JE; Choy BC; Tokarz P; Chin CF; Quek DQY; Kloss B; Pepe JG; Parisi G; Wong BH; Clarke OB; Marty MT; Kossiakoff AA; Khelashvili G; Silver DL; Mancia F
Nature; 2021 Jul; 595(7866):315-319. PubMed ID: 34135507
[TBL] [Abstract][Full Text] [Related]
3. Mfsd2a utilizes a flippase mechanism to mediate omega-3 fatty acid lysolipid transport.
Chua GL; Tan BC; Loke RYJ; He M; Chin CF; Wong BH; Kuk ACY; Ding M; Wenk MR; Guan L; Torta F; Silver DL
Proc Natl Acad Sci U S A; 2023 Mar; 120(10):e2215290120. PubMed ID: 36848557
[TBL] [Abstract][Full Text] [Related]
4. Lipid flipping in the omega-3 fatty-acid transporter.
Nguyen C; Lei HT; Lai LTF; Gallenito MJ; Mu X; Matthies D; Gonen T
Nat Commun; 2023 May; 14(1):2571. PubMed ID: 37156797
[TBL] [Abstract][Full Text] [Related]
5. Structural Insights into the Transport Mechanism of the Human Sodium-dependent Lysophosphatidylcholine Transporter MFSD2A.
Quek DQ; Nguyen LN; Fan H; Silver DL
J Biol Chem; 2016 Apr; 291(18):9383-94. PubMed ID: 26945070
[TBL] [Abstract][Full Text] [Related]
6. Mfsd2a is a transporter for the essential omega-3 fatty acid docosahexaenoic acid.
Nguyen LN; Ma D; Shui G; Wong P; Cazenave-Gassiot A; Zhang X; Wenk MR; Goh EL; Silver DL
Nature; 2014 May; 509(7501):503-6. PubMed ID: 24828044
[TBL] [Abstract][Full Text] [Related]
7. Mfsd2a: A Physiologically Important Lysolipid Transporter in the Brain and Eye.
Wong BH; Silver DL
Adv Exp Med Biol; 2020; 1276():223-234. PubMed ID: 32705603
[TBL] [Abstract][Full Text] [Related]
8. Mfsd2a Is a Transporter for the Essential ω-3 Fatty Acid Docosahexaenoic Acid (DHA) in Eye and Is Important for Photoreceptor Cell Development.
Wong BH; Chan JP; Cazenave-Gassiot A; Poh RW; Foo JC; Galam DL; Ghosh S; Nguyen LN; Barathi VA; Yeo SW; Luu CD; Wenk MR; Silver DL
J Biol Chem; 2016 May; 291(20):10501-14. PubMed ID: 27008858
[TBL] [Abstract][Full Text] [Related]
9. Knockdown of Placental Major Facilitator Superfamily Domain Containing 2a in Pregnant Mice Reduces Fetal Brain Growth and Phospholipid Docosahexaenoic Acid Content.
Powell TL; Barentsen K; Vaughan O; Uhlson C; Zemski Berry K; Erickson K; Faer K; Chassen SS; Jansson T
Nutrients; 2023 Nov; 15(23):. PubMed ID: 38068814
[TBL] [Abstract][Full Text] [Related]
10. Structural insights into the lysophospholipid brain uptake mechanism and its inhibition by syncytin-2.
Martinez-Molledo M; Nji E; Reyes N
Nat Struct Mol Biol; 2022 Jun; 29(6):604-612. PubMed ID: 35710838
[TBL] [Abstract][Full Text] [Related]
11. Deficiency in the omega-3 lysolipid transporter Mfsd2a leads to aberrant oligodendrocyte lineage development and hypomyelination.
Sengottuvel V; Hota M; Oh J; Galam DL; Wong BH; Wenk MR; Ghosh S; Torta F; Silver DL
J Clin Invest; 2023 Jun; 133(12):. PubMed ID: 37104036
[TBL] [Abstract][Full Text] [Related]
12. Zika virus degrades the ω-3 fatty acid transporter Mfsd2a in brain microvascular endothelial cells and impairs lipid homeostasis.
Zhou J; Chi X; Cheng M; Huang X; Liu X; Fan J; Xu H; Lin T; Shi L; Qin C; Yang W
Sci Adv; 2019 Oct; 5(10):eaax7142. PubMed ID: 31681849
[TBL] [Abstract][Full Text] [Related]
13. Inactivating mutations in MFSD2A, required for omega-3 fatty acid transport in brain, cause a lethal microcephaly syndrome.
Guemez-Gamboa A; Nguyen LN; Yang H; Zaki MS; Kara M; Ben-Omran T; Akizu N; Rosti RO; Rosti B; Scott E; Schroth J; Copeland B; Vaux KK; Cazenave-Gassiot A; Quek DQ; Wong BH; Tan BC; Wenk MR; Gunel M; Gabriel S; Chi NC; Silver DL; Gleeson JG
Nat Genet; 2015 Jul; 47(7):809-13. PubMed ID: 26005868
[TBL] [Abstract][Full Text] [Related]
14. Basic residues R260 and K357 affect the conformational dynamics of the major facilitator superfamily multidrug transporter LmrP.
Wang W; van Veen HW
PLoS One; 2012; 7(6):e38715. PubMed ID: 22761697
[TBL] [Abstract][Full Text] [Related]
15. Structure and mechanism of blood-brain-barrier lipid transporter MFSD2A.
Wood CAP; Zhang J; Aydin D; Xu Y; Andreone BJ; Langen UH; Dror RO; Gu C; Feng L
Nature; 2021 Aug; 596(7872):444-448. PubMed ID: 34349262
[TBL] [Abstract][Full Text] [Related]
16. Mfsd2a encodes a novel major facilitator superfamily domain-containing protein highly induced in brown adipose tissue during fasting and adaptive thermogenesis.
Angers M; Uldry M; Kong D; Gimble JM; Jetten AM
Biochem J; 2008 Dec; 416(3):347-55. PubMed ID: 18694395
[TBL] [Abstract][Full Text] [Related]
17. Marine Fish-Derived Lysophosphatidylcholine: Properties, Extraction, Quantification, and Brain Health Application.
Ahmmed MK; Hachem M; Ahmmed F; Rashidinejad A; Oz F; Bekhit AA; Carne A; Bekhit AEA
Molecules; 2023 Mar; 28(7):. PubMed ID: 37049852
[TBL] [Abstract][Full Text] [Related]
18. The lysolipid transporter Mfsd2a regulates lipogenesis in the developing brain.
Chan JP; Wong BH; Chin CF; Galam DLA; Foo JC; Wong LC; Ghosh S; Wenk MR; Cazenave-Gassiot A; Silver DL
PLoS Biol; 2018 Aug; 16(8):e2006443. PubMed ID: 30074985
[TBL] [Abstract][Full Text] [Related]
19. The lipid transporter Mfsd2a maintains pulmonary surfactant homeostasis.
Wong BH; Mei D; Chua GL; Galam DL; Wenk MR; Torta F; Silver DL
J Biol Chem; 2022 Mar; 298(3):101709. PubMed ID: 35150739
[TBL] [Abstract][Full Text] [Related]
20. Insights into major facilitator superfamily domain-containing protein-2a (Mfsd2a) in physiology and pathophysiology. What do we know so far?
Eser Ocak P; Ocak U; Sherchan P; Zhang JH; Tang J
J Neurosci Res; 2020 Jan; 98(1):29-41. PubMed ID: 30345547
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
