These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

209 related articles for article (PubMed ID: 37304004)

  • 1. Rational design, synthesis and structural characterization of peptides and peptidomimetics to target Hsp90/Cdc37 interaction for treating hepatocellular carcinoma.
    Sukumaran S; Tan M; Ben-Uliel SF; Zhang H; De Zotti M; Chua MS; So SK; Qvit N
    Comput Struct Biotechnol J; 2023; 21():3159-3172. PubMed ID: 37304004
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Exploring Biomolecular Interaction Between the Molecular Chaperone Hsp90 and Its Client Protein Kinase Cdc37 using Field-Effect Biosensing Technology.
    Lerner Y; Sukumaran S; Chua MS; So SK; Qvit N
    J Vis Exp; 2022 Mar; (181):. PubMed ID: 35435890
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Hsp90/Cdc37 chaperone/co-chaperone complex, a novel junction anticancer target elucidated by the mode of action of herbal drug Withaferin A.
    Grover A; Shandilya A; Agrawal V; Pratik P; Bhasme D; Bisaria VS; Sundar D
    BMC Bioinformatics; 2011 Feb; 12 Suppl 1(Suppl 1):S30. PubMed ID: 21342561
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The Therapeutic Potential of Targeting Hsp90-Cdc37 Interactions in Several Diseases.
    Zhang X; Li S; Li Z; Cheng L; Liu Z; Wang C
    Curr Drug Targets; 2022; 23(10):1023-1038. PubMed ID: 35400341
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Targeting the Hsp90-Cdc37-client protein interaction to disrupt Hsp90 chaperone machinery.
    Li T; Jiang HL; Tong YG; Lu JJ
    J Hematol Oncol; 2018 Apr; 11(1):59. PubMed ID: 29699578
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design, synthesis and bioevaluation of inhibitors targeting HSP90-CDC37 protein-protein interaction based on a hydrophobic core.
    Zhang Q; Wu X; Zhou J; Zhang L; Xu X; Zhang L; You Q; Wang L
    Eur J Med Chem; 2021 Jan; 210():112959. PubMed ID: 33109397
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Rational design of peptide inhibitors targeting HSP90-CDC37 protein-protein interaction.
    Zhang Q; Yan L; Zhang Y; Zhang L; Yu J; You Q; Wang L
    Future Med Chem; 2024 Jan; 16(2):125-138. PubMed ID: 38189168
    [No Abstract]   [Full Text] [Related]  

  • 8. Serine/Threonine Kinase Unc-51-like Kinase-1 (Ulk1) Phosphorylates the Co-chaperone Cell Division Cycle Protein 37 (Cdc37) and Thereby Disrupts the Stability of Cdc37 Client Proteins.
    Li R; Yuan F; Fu W; Zhang L; Zhang N; Wang Y; Ma K; Li X; Wang L; Zhu WG; Zhao Y
    J Biol Chem; 2017 Feb; 292(7):2830-2841. PubMed ID: 28073914
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Optimization and bioevaluation of Cdc37-derived peptides: An insight into Hsp90-Cdc37 protein-protein interaction modulators.
    Wang L; Li L; Fu WT; Jiang ZY; You QD; Xu XL
    Bioorg Med Chem; 2017 Jan; 25(1):233-240. PubMed ID: 27818030
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cdc37 (cell division cycle 37) restricts Hsp90 (heat shock protein 90) motility by interaction with N-terminal and middle domain binding sites.
    Eckl JM; Rutz DA; Haslbeck V; Zierer BK; Reinstein J; Richter K
    J Biol Chem; 2013 May; 288(22):16032-42. PubMed ID: 23569206
    [TBL] [Abstract][Full Text] [Related]  

  • 11. FW-04-806 inhibits proliferation and induces apoptosis in human breast cancer cells by binding to N-terminus of Hsp90 and disrupting Hsp90-Cdc37 complex formation.
    Huang W; Ye M; Zhang LR; Wu QD; Zhang M; Xu JH; Zheng W
    Mol Cancer; 2014 Jun; 13():150. PubMed ID: 24927996
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Hsp90·Cdc37 Complexes with Protein Kinases Form Cooperatively with Multiple Distinct Interaction Sites.
    Eckl JM; Scherr MJ; Freiburger L; Daake MA; Sattler M; Richter K
    J Biol Chem; 2015 Dec; 290(52):30843-54. PubMed ID: 26511315
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Okicamelliaside targets the N-terminal chaperone pocket of HSP90 disrupts the chaperone protein interaction of HSP90-CDC37 and exerts antitumor activity.
    Cheng CJ; Liu KX; Zhang M; Shen FK; Ye LL; Wu WB; Hou XT; Hao EW; Hou YY; Bai G
    Acta Pharmacol Sin; 2022 Apr; 43(4):1046-1058. PubMed ID: 34326484
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Targeting the HSP90-CDC37-kinase chaperone cycle: A promising therapeutic strategy for cancer.
    Wang L; Zhang Q; You Q
    Med Res Rev; 2022 Jan; 42(1):156-182. PubMed ID: 33846988
    [TBL] [Abstract][Full Text] [Related]  

  • 15.
    Dike PP; Bhowmick S; Eldesoky GE; Wabaidur SM; Patil PC; Islam MA
    J Biomol Struct Dyn; 2022 Mar; 40(5):2082-2098. PubMed ID: 33095103
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cdc37 as a Co-chaperone to Hsp90.
    Prince TL; Lang BJ; Okusha Y; Eguchi T; Calderwood SK
    Subcell Biochem; 2023; 101():141-158. PubMed ID: 36520306
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Functional Role and Hierarchy of the Intermolecular Interactions in Binding of Protein Kinase Clients to the Hsp90-Cdc37 Chaperone: Structure-Based Network Modeling of Allosteric Regulation.
    Stetz G; Verkhivker GM
    J Chem Inf Model; 2018 Feb; 58(2):405-421. PubMed ID: 29432007
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Small-molecule inhibitor targeting the Hsp90-Cdc37 protein-protein interaction in colorectal cancer.
    Wang L; Zhang L; Li L; Jiang J; Zheng Z; Shang J; Wang C; Chen W; Bao Q; Xu X; Jiang Z; Zhang J; You Q
    Sci Adv; 2019 Sep; 5(9):eaax2277. PubMed ID: 31555737
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Restricting direct interaction of CDC37 with HSP90 does not compromise chaperoning of client proteins.
    Smith JR; de Billy E; Hobbs S; Powers M; Prodromou C; Pearl L; Clarke PA; Workman P
    Oncogene; 2015 Jan; 34(1):15-26. PubMed ID: 24292678
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Discovery of Novel Celastrol Derivatives as Hsp90-Cdc37 Interaction Disruptors with Antitumor Activity.
    Li N; Xu M; Wang B; Shi Z; Zhao Z; Tang Y; Wang X; Sun J; Chen L
    J Med Chem; 2019 Dec; 62(23):10798-10815. PubMed ID: 31725288
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.