BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

155 related articles for article (PubMed ID: 37307219)

  • 41. Identification of hematein as a novel inhibitor of protein kinase CK2 from a natural product library.
    Hung MS; Xu Z; Lin YC; Mao JH; Yang CT; Chang PJ; Jablons DM; You L
    BMC Cancer; 2009 May; 9():135. PubMed ID: 19419583
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Selectivity of 4,5,6,7-tetrabromobenzotriazole, an ATP site-directed inhibitor of protein kinase CK2 ('casein kinase-2').
    Sarno S; Reddy H; Meggio F; Ruzzene M; Davies SP; Donella-Deana A; Shugar D; Pinna LA
    FEBS Lett; 2001 May; 496(1):44-8. PubMed ID: 11343704
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Structural basis of CX-4945 binding to human protein kinase CK2.
    Ferguson AD; Sheth PR; Basso AD; Paliwal S; Gray K; Fischmann TO; Le HV
    FEBS Lett; 2011 Jan; 585(1):104-10. PubMed ID: 21093442
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Casein Kinase II (CK2) as a Therapeutic Target for Hematological Malignancies.
    Gowda C; Sachdev M; Muthusami S; Kapadia M; Petrovic-Dovat L; Hartman M; Ding Y; Song C; Payne JL; Tan BH; Dovat S
    Curr Pharm Des; 2017; 23(1):95-107. PubMed ID: 27719640
    [TBL] [Abstract][Full Text] [Related]  

  • 45. The replacement of ATP by the competitive inhibitor emodin induces conformational modifications in the catalytic site of protein kinase CK2.
    Battistutta R; Sarno S; De Moliner E; Papinutto E; Zanotti G; Pinna LA
    J Biol Chem; 2000 Sep; 275(38):29618-22. PubMed ID: 10882732
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Discovery of novel CK2 leads by cross-docking based virtual screening.
    Sun H; Wu X; Xu X; Jiang Z; Liu Z; You Q
    Med Chem; 2014; 10(6):628-39. PubMed ID: 24286395
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Conformational plasticity of the catalytic subunit of protein kinase CK2 and its consequences for regulation and drug design.
    Niefind K; Issinger OG
    Biochim Biophys Acta; 2010 Mar; 1804(3):484-92. PubMed ID: 19796713
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Comparing the efficacy and selectivity of Ck2 inhibitors. A phosphoproteomics approach.
    Borgo C; Cesaro L; Hirota T; Kuwata K; D'Amore C; Ruppert T; Blatnik R; Salvi M; Pinna LA
    Eur J Med Chem; 2021 Mar; 214():113217. PubMed ID: 33548633
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Exploring the Pivotal Role of the CK2 Hinge Region Sub-Pocket in Binding with Tricyclic Quinolone Analogues by Computational Analysis.
    Zhou Y; Zhang N; Tang S; Qi X; Zhao L; Zhong R; Peng Y
    Molecules; 2017 May; 22(5):. PubMed ID: 28534839
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Malaria protein kinase CK2 (PfCK2) shows novel mechanisms of regulation.
    Graciotti M; Alam M; Solyakov L; Schmid R; Burley G; Bottrill AR; Doerig C; Cullis P; Tobin AB
    PLoS One; 2014; 9(3):e85391. PubMed ID: 24658579
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Discovery and SAR of 5-(3-chlorophenylamino)benzo[c][2,6]naphthyridine-8-carboxylic acid (CX-4945), the first clinical stage inhibitor of protein kinase CK2 for the treatment of cancer.
    Pierre F; Chua PC; O'Brien SE; Siddiqui-Jain A; Bourbon P; Haddach M; Michaux J; Nagasawa J; Schwaebe MK; Stefan E; Vialettes A; Whitten JP; Chen TK; Darjania L; Stansfield R; Anderes K; Bliesath J; Drygin D; Ho C; Omori M; Proffitt C; Streiner N; Trent K; Rice WG; Ryckman DM
    J Med Chem; 2011 Jan; 54(2):635-54. PubMed ID: 21174434
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Inclining the purine base binding plane in protein kinase CK2 by exchanging the flanking side-chains generates a preference for ATP as a cosubstrate.
    Yde CW; Ermakova I; Issinger OG; Niefind K
    J Mol Biol; 2005 Mar; 347(2):399-414. PubMed ID: 15740749
    [TBL] [Abstract][Full Text] [Related]  

  • 53. The catalytic subunit of human protein kinase CK2 structurally deviates from its maize homologue in complex with the nucleotide competitive inhibitor emodin.
    Raaf J; Klopffleisch K; Issinger OG; Niefind K
    J Mol Biol; 2008 Mar; 377(1):1-8. PubMed ID: 18242640
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Protein kinase CK2 as a druggable target.
    Sarno S; Pinna LA
    Mol Biosyst; 2008 Sep; 4(9):889-94. PubMed ID: 18704226
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Synthesis, biological properties and structural study of new halogenated azolo[4,5-b]pyridines as inhibitors of CK2 kinase.
    Chojnacki K; Lindenblatt D; Wińska P; Wielechowska M; Toelzer C; Niefind K; Bretner M
    Bioorg Chem; 2021 Jan; 106():104502. PubMed ID: 33317841
    [TBL] [Abstract][Full Text] [Related]  

  • 56. An overview about the impact of hinge region towards the anticancer binding affinity of the Ck2 ligands: a quantum chemical analysis.
    Deepa P; Thirumeignanam D; Kolandaivel P
    J Biomol Struct Dyn; 2019 Sep; 37(15):3859-3876. PubMed ID: 30301411
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Benzimidazole inhibitors of protein kinase CK2 potently inhibit the activity of atypical protein kinase Rio1.
    Kubiński K; Masłyk M; Orzeszko A
    Mol Cell Biochem; 2017 Feb; 426(1-2):195-203. PubMed ID: 27909846
    [TBL] [Abstract][Full Text] [Related]  

  • 58. A promiscuous kinase inhibitor delineates the conspicuous structural features of protein kinase CK2a1.
    Tsuyuguchi M; Nakaniwa T; Sawa M; Nakanishi I; Kinoshita T
    Acta Crystallogr F Struct Biol Commun; 2019 Jul; 75(Pt 7):515-519. PubMed ID: 31282872
    [TBL] [Abstract][Full Text] [Related]  

  • 59. A fragment-based approach leading to the discovery of a novel binding site and the selective CK2 inhibitor CAM4066.
    De Fusco C; Brear P; Iegre J; Georgiou KH; Sore HF; Hyvönen M; Spring DR
    Bioorg Med Chem; 2017 Jul; 25(13):3471-3482. PubMed ID: 28495381
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Inspecting the structure-activity relationship of protein kinase CK2 inhibitors derived from tetrabromo-benzimidazole.
    Battistutta R; Mazzorana M; Sarno S; Kazimierczuk Z; Zanotti G; Pinna LA
    Chem Biol; 2005 Nov; 12(11):1211-9. PubMed ID: 16298300
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.