These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

180 related articles for article (PubMed ID: 37315086)

  • 1. Structural basis for proapoptotic activation of Bak by the noncanonical BH3-only protein Pxt1.
    Lim D; Choe SH; Jin S; Lee S; Kim Y; Shin HC; Choi JS; Oh DB; Kim SJ; Seo J; Ku B
    PLoS Biol; 2023 Jun; 21(6):e3002156. PubMed ID: 37315086
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structural and biochemical analyses of Bcl-xL in complex with the BH3 domain of peroxisomal testis-specific 1.
    Lim D; Jin S; Shin HC; Kim W; Choi JS; Oh DB; Kim SJ; Seo J; Ku B
    Biochem Biophys Res Commun; 2022 Oct; 625():174-180. PubMed ID: 35964379
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Crystal structure of Bak bound to the BH3 domain of Bnip5, a noncanonical BH3 domain-containing protein.
    Lim D; Jeong DE; Shin HC; Choi JS; Seo J; Kim SJ; Ku B
    Proteins; 2024 Jan; 92(1):44-51. PubMed ID: 37553948
    [TBL] [Abstract][Full Text] [Related]  

  • 4. BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis.
    Cheng EH; Wei MC; Weiler S; Flavell RA; Mak TW; Lindsten T; Korsmeyer SJ
    Mol Cell; 2001 Sep; 8(3):705-11. PubMed ID: 11583631
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structural basis of BAK activation in mitochondrial apoptosis initiation.
    Singh G; Guibao CD; Seetharaman J; Aggarwal A; Grace CR; McNamara DE; Vaithiyalingam S; Waddell MB; Moldoveanu T
    Nat Commun; 2022 Jan; 13(1):250. PubMed ID: 35017502
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The BH3 alpha-helical mimic BH3-M6 disrupts Bcl-X(L), Bcl-2, and MCL-1 protein-protein interactions with Bax, Bak, Bad, or Bim and induces apoptosis in a Bax- and Bim-dependent manner.
    Kazi A; Sun J; Doi K; Sung SS; Takahashi Y; Yin H; Rodriguez JM; Becerril J; Berndt N; Hamilton AD; Wang HG; Sebti SM
    J Biol Chem; 2011 Mar; 286(11):9382-92. PubMed ID: 21148306
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Bid chimeras indicate that most BH3-only proteins can directly activate Bak and Bax, and show no preference for Bak versus Bax.
    Hockings C; Anwari K; Ninnis RL; Brouwer J; O'Hely M; Evangelista M; Hinds MG; Czabotar PE; Lee EF; Fairlie WD; Dewson G; Kluck RM
    Cell Death Dis; 2015 Apr; 6(4):e1735. PubMed ID: 25906158
    [TBL] [Abstract][Full Text] [Related]  

  • 8. To trigger apoptosis, Bak exposes its BH3 domain and homodimerizes via BH3:groove interactions.
    Dewson G; Kratina T; Sim HW; Puthalakath H; Adams JM; Colman PM; Kluck RM
    Mol Cell; 2008 May; 30(3):369-80. PubMed ID: 18471982
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Involvement of proapoptotic molecules Bax and Bak in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced mitochondrial disruption and apoptosis: differential regulation of cytochrome c and Smac/DIABLO release.
    Kandasamy K; Srinivasula SM; Alnemri ES; Thompson CB; Korsmeyer SJ; Bryant JL; Srivastava RK
    Cancer Res; 2003 Apr; 63(7):1712-21. PubMed ID: 12670926
    [TBL] [Abstract][Full Text] [Related]  

  • 10. p14(ARF)-induced apoptosis in p53 protein-deficient cells is mediated by BH3-only protein-independent derepression of Bak protein through down-regulation of Mcl-1 and Bcl-xL proteins.
    Müer A; Overkamp T; Gillissen B; Richter A; Pretzsch T; Milojkovic A; Dörken B; Daniel PT; Hemmati P
    J Biol Chem; 2012 May; 287(21):17343-17352. PubMed ID: 22354970
    [TBL] [Abstract][Full Text] [Related]  

  • 11. BAK α6 permits activation by BH3-only proteins and homooligomerization via the canonical hydrophobic groove.
    Li MX; Tan IKL; Ma SB; Hockings C; Kratina T; Dengler MA; Alsop AE; Kluck RM; Dewson G
    Proc Natl Acad Sci U S A; 2017 Jul; 114(29):7629-7634. PubMed ID: 28673969
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Nuclear magnetic resonance study of protein-protein interactions involving apoptosis regulator Diva (Boo) and the BH3 domain of proapoptotic Bcl-2 members.
    Santiveri CM; Sborgi L; de Alba E
    J Mol Recognit; 2012 Dec; 25(12):665-73. PubMed ID: 23192964
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Interferon-alpha-induced apoptosis in U266 cells is associated with activation of the proapoptotic Bcl-2 family members Bak and Bax.
    Panaretakis T; Pokrovskaja K; Shoshan MC; Grandér D
    Oncogene; 2003 Jul; 22(29):4543-56. PubMed ID: 12881711
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Methods to Probe Conformational Activation and Mitochondrial Activity of Proapoptotic BAK.
    Singh G; Moldoveanu T
    Methods Mol Biol; 2019; 1877():185-200. PubMed ID: 30536007
    [TBL] [Abstract][Full Text] [Related]  

  • 15. BH3 domains other than Bim and Bid can directly activate Bax/Bak.
    Du H; Wolf J; Schafer B; Moldoveanu T; Chipuk JE; Kuwana T
    J Biol Chem; 2011 Jan; 286(1):491-501. PubMed ID: 21041309
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mitochondrial permeabilization relies on BH3 ligands engaging multiple prosurvival Bcl-2 relatives, not Bak.
    Uren RT; Dewson G; Chen L; Coyne SC; Huang DC; Adams JM; Kluck RM
    J Cell Biol; 2007 Apr; 177(2):277-87. PubMed ID: 17452531
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death.
    Wei MC; Zong WX; Cheng EH; Lindsten T; Panoutsakopoulou V; Ross AJ; Roth KA; MacGregor GR; Thompson CB; Korsmeyer SJ
    Science; 2001 Apr; 292(5517):727-30. PubMed ID: 11326099
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Bcl-XL protects BimEL-induced Bax conformational change and cytochrome C release independent of interacting with Bax or BimEL.
    Yamaguchi H; Wang HG
    J Biol Chem; 2002 Nov; 277(44):41604-12. PubMed ID: 12198137
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Transient binding of an activator BH3 domain to the Bak BH3-binding groove initiates Bak oligomerization.
    Dai H; Smith A; Meng XW; Schneider PA; Pang YP; Kaufmann SH
    J Cell Biol; 2011 Jul; 194(1):39-48. PubMed ID: 21727192
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Peptides from human BNIP5 and PXT1 and non-native binders of pro-apoptotic BAK can directly activate or inhibit BAK-mediated membrane permeabilization.
    Aguilar F; Yu S; Grant RA; Swanson S; Ghose D; Su BG; Sarosiek KA; Keating AE
    Structure; 2023 Mar; 31(3):265-281.e7. PubMed ID: 36706751
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.