These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

125 related articles for article (PubMed ID: 37319115)

  • 1. C9orf72 poly-PR helps p53 escape from the ubiquitin-proteasome system and promotes its stability.
    Yang F; Mahaman YAR; Zhang B; Wang JZ; Liu R; Liu F; Wang X
    J Neurochem; 2023 Jul; 166(2):389-402. PubMed ID: 37319115
    [TBL] [Abstract][Full Text] [Related]  

  • 2. C9orf72 Dipeptide Repeats Cause Selective Neurodegeneration and Cell-Autonomous Excitotoxicity in
    Xu W; Xu J
    J Neurosci; 2018 Aug; 38(35):7741-7752. PubMed ID: 30037833
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Sense-encoded poly-GR dipeptide repeat proteins correlate to neurodegeneration and uniquely co-localize with TDP-43 in dendrites of repeat-expanded C9orf72 amyotrophic lateral sclerosis.
    Saberi S; Stauffer JE; Jiang J; Garcia SD; Taylor AE; Schulte D; Ohkubo T; Schloffman CL; Maldonado M; Baughn M; Rodriguez MJ; Pizzo D; Cleveland D; Ravits J
    Acta Neuropathol; 2018 Mar; 135(3):459-474. PubMed ID: 29196813
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The contribution of proteasomal impairment to autophagy activation by C9orf72 poly-GA aggregates.
    Pu M; Tai Y; Yuan L; Zhang Y; Guo H; Hao Z; Chen J; Qi X; Wang G; Tao Z; Ren J
    Cell Mol Life Sci; 2022 Aug; 79(9):501. PubMed ID: 36036324
    [TBL] [Abstract][Full Text] [Related]  

  • 5. CRISPR/Cas9 screen in human iPSC-derived cortical neurons identifies NEK6 as a novel disease modifier of C9orf72 poly(PR) toxicity.
    Guo W; Wang H; Kumar Tharkeshwar A; Couthouis J; Braems E; Masrori P; Van Schoor E; Fan Y; Ahuja K; Moisse M; Jacquemyn M; Furtado Madeiro da Costa R; Gajjar M; Balusu S; Tricot T; Fumagalli L; Hersmus N; Janky R; Impens F; Vanden Berghe P; Ho R; Thal DR; Vandenberghe R; Hegde ML; Chandran S; De Strooper B; Daelemans D; Van Damme P; Van Den Bosch L; Verfaillie C
    Alzheimers Dement; 2023 Apr; 19(4):1245-1259. PubMed ID: 35993441
    [TBL] [Abstract][Full Text] [Related]  

  • 6. C9orf72 ALS-FTD: recent evidence for dysregulation of the autophagy-lysosome pathway at multiple levels.
    Beckers J; Tharkeshwar AK; Van Damme P
    Autophagy; 2021 Nov; 17(11):3306-3322. PubMed ID: 33632058
    [TBL] [Abstract][Full Text] [Related]  

  • 7. c-Jun N-Terminal Kinase Promotes Stress Granule Assembly and Neurodegeneration in C9orf72-Mediated ALS and FTD.
    Sahana TG; Chase KJ; Liu F; Lloyd TE; Rossoll W; Zhang K
    J Neurosci; 2023 Apr; 43(17):3186-3197. PubMed ID: 37015810
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Proline-arginine poly-dipeptide encoded by the C9orf72 repeat expansion inhibits adenosine deaminase acting on RNA.
    Suzuki H; Matsuoka M
    J Neurochem; 2021 Aug; 158(3):753-765. PubMed ID: 34081786
    [TBL] [Abstract][Full Text] [Related]  

  • 9. p53 is a central regulator driving neurodegeneration caused by C9orf72 poly(PR).
    Maor-Nof M; Shipony Z; Lopez-Gonzalez R; Nakayama L; Zhang YJ; Couthouis J; Blum JA; Castruita PA; Linares GR; Ruan K; Ramaswami G; Simon DJ; Nof A; Santana M; Han K; Sinnott-Armstrong N; Bassik MC; Geschwind DH; Tessier-Lavigne M; Attardi LD; Lloyd TE; Ichida JK; Gao FB; Greenleaf WJ; Yokoyama JS; Petrucelli L; Gitler AD
    Cell; 2021 Feb; 184(3):689-708.e20. PubMed ID: 33482083
    [TBL] [Abstract][Full Text] [Related]  

  • 10. ZNF598 co-translationally titrates poly(GR) protein implicated in the pathogenesis of C9ORF72-associated ALS/FTD.
    Park J; Lee J; Kim JH; Lee J; Park H; Lim C
    Nucleic Acids Res; 2021 Nov; 49(19):11294-11311. PubMed ID: 34551427
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The DNA damage response (DDR) is induced by the C9orf72 repeat expansion in amyotrophic lateral sclerosis.
    Farg MA; Konopka A; Soo KY; Ito D; Atkin JD
    Hum Mol Genet; 2017 Aug; 26(15):2882-2896. PubMed ID: 28481984
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Arginine-rich dipeptide-repeat proteins as phase disruptors in C9-ALS/FTD.
    Odeh HM; Shorter J
    Emerg Top Life Sci; 2020 Dec; 4(3):293-305. PubMed ID: 32639008
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Dipeptide repeat proteins inhibit homology-directed DNA double strand break repair in C9ORF72 ALS/FTD.
    Andrade NS; Ramic M; Esanov R; Liu W; Rybin MJ; Gaidosh G; Abdallah A; Del'Olio S; Huff TC; Chee NT; Anatha S; Gendron TF; Wahlestedt C; Zhang Y; Benatar M; Mueller C; Zeier Z
    Mol Neurodegener; 2020 Feb; 15(1):13. PubMed ID: 32093728
    [TBL] [Abstract][Full Text] [Related]  

  • 14.
    Cicardi ME; Hallgren JH; Mawrie D; Krishnamurthy K; Markandaiah SS; Nelson AT; Kankate V; Anderson EN; Pasinelli P; Pandey UB; Eischen CM; Trotti D
    bioRxiv; 2023 Feb; ():. PubMed ID: 36824930
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Characterization of the dipeptide repeat protein in the molecular pathogenesis of c9FTD/ALS.
    Yamakawa M; Ito D; Honda T; Kubo K; Noda M; Nakajima K; Suzuki N
    Hum Mol Genet; 2015 Mar; 24(6):1630-45. PubMed ID: 25398948
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Open Access: A Role for p53 in c9ALS/FTD?
    Fare CM; Shorter J
    Trends Genet; 2021 May; 37(5):404-406. PubMed ID: 33551183
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Poly-PR in C9ORF72-Related Amyotrophic Lateral Sclerosis/Frontotemporal Dementia Causes Neurotoxicity by Clathrin-Dependent Endocytosis.
    Wang R; Xu X; Hao Z; Zhang S; Wu D; Sun H; Mu C; Ren H; Wang G
    Neurosci Bull; 2019 Oct; 35(5):889-900. PubMed ID: 31148094
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Evidence that C9ORF72 Dipeptide Repeat Proteins Associate with U2 snRNP to Cause Mis-splicing in ALS/FTD Patients.
    Yin S; Lopez-Gonzalez R; Kunz RC; Gangopadhyay J; Borufka C; Gygi SP; Gao FB; Reed R
    Cell Rep; 2017 Jun; 19(11):2244-2256. PubMed ID: 28614712
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Nucleolar stress and impaired stress granule formation contribute to C9orf72 RAN translation-induced cytotoxicity.
    Tao Z; Wang H; Xia Q; Li K; Li K; Jiang X; Xu G; Wang G; Ying Z
    Hum Mol Genet; 2015 May; 24(9):2426-41. PubMed ID: 25575510
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The proline-arginine repeat protein linked to C9-ALS/FTD causes neuronal toxicity by inhibiting the DEAD-box RNA helicase-mediated ribosome biogenesis.
    Suzuki H; Shibagaki Y; Hattori S; Matsuoka M
    Cell Death Dis; 2018 Sep; 9(10):975. PubMed ID: 30250194
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.