BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

395 related articles for article (PubMed ID: 37337279)

  • 1. Humanized APOE genotypes influence lifespan independently of tau aggregation in the P301S mouse model of tauopathy.
    Williams T; Bathe T; Vo Q; Sacilotto P; McFarland K; Ruiz AJ; Hery GP; Sullivan P; Borchelt DR; Prokop S; Chakrabarty P
    Acta Neuropathol Commun; 2023 Jun; 11(1):99. PubMed ID: 37337279
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Impact of APOE genotype on prion-type propagation of tauopathy.
    Williams T; Ruiz AJ; Ruiz AM; Vo Q; Tsering W; Xu G; McFarland K; Giasson BI; Sullivan P; Borchelt DR; Chakrabarty P
    Acta Neuropathol Commun; 2022 Apr; 10(1):57. PubMed ID: 35440098
    [TBL] [Abstract][Full Text] [Related]  

  • 3. ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy.
    Shi Y; Yamada K; Liddelow SA; Smith ST; Zhao L; Luo W; Tsai RM; Spina S; Grinberg LT; Rojas JC; Gallardo G; Wang K; Roh J; Robinson G; Finn MB; Jiang H; Sullivan PM; Baufeld C; Wood MW; Sutphen C; McCue L; Xiong C; Del-Aguila JL; Morris JC; Cruchaga C; ; Fagan AM; Miller BL; Boxer AL; Seeley WW; Butovsky O; Barres BA; Paul SM; Holtzman DM
    Nature; 2017 Sep; 549(7673):523-527. PubMed ID: 28959956
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Plasma ApoE4 Levels Are Lower than ApoE2 and ApoE3 Levels, and Not Associated with Plasma Aβ40/42 Ratio as a Biomarker of Amyloid-β Amyloidosis in Alzheimer's Disease.
    Nakamura T; Kawarabayashi T; Ueda T; Shimomura S; Hoshino M; Itoh K; Ihara K; Nakaji S; Takatama M; Ikeda Y; Shoji M
    J Alzheimers Dis; 2023; 93(1):333-348. PubMed ID: 36970894
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Differential Signaling Mediated by ApoE2, ApoE3, and ApoE4 in Human Neurons Parallels Alzheimer's Disease Risk.
    Huang YA; Zhou B; Nabet AM; Wernig M; Südhof TC
    J Neurosci; 2019 Sep; 39(37):7408-7427. PubMed ID: 31331998
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Amelioration of Tau and ApoE4-linked glial lipid accumulation and neurodegeneration with an LXR agonist.
    Litvinchuk A; Suh JH; Guo JL; Lin K; Davis SS; Bien-Ly N; Tycksen E; Tabor GT; Remolina Serrano J; Manis M; Bao X; Lee C; Bosch M; Perez EJ; Yuede CM; Cashikar AG; Ulrich JD; Di Paolo G; Holtzman DM
    Neuron; 2024 Feb; 112(3):384-403.e8. PubMed ID: 37995685
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Interaction of nascent ApoE2, ApoE3, and ApoE4 isoforms expressed in mammalian cells with amyloid peptide beta (1-40). Relevance to Alzheimer's disease.
    Aleshkov S; Abraham CR; Zannis VI
    Biochemistry; 1997 Aug; 36(34):10571-80. PubMed ID: 9265639
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Neuron-specific apolipoprotein e4 proteolysis is associated with increased tau phosphorylation in brains of transgenic mice.
    Brecht WJ; Harris FM; Chang S; Tesseur I; Yu GQ; Xu Q; Dee Fish J; Wyss-Coray T; Buttini M; Mucke L; Mahley RW; Huang Y
    J Neurosci; 2004 Mar; 24(10):2527-34. PubMed ID: 15014128
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Opposing effects of viral mediated brain expression of apolipoprotein E2 (apoE2) and apoE4 on apoE lipidation and Aβ metabolism in apoE4-targeted replacement mice.
    Hu J; Liu CC; Chen XF; Zhang YW; Xu H; Bu G
    Mol Neurodegener; 2015 Mar; 10():6. PubMed ID: 25871773
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Accumulation of amyloid-β in the brain of mouse models of Alzheimer's disease is modified by altered gene expression in the presence of human apoE isoforms during aging.
    Honda K; Saito Y; Saito H; Toyoda M; Abe R; Saito T; Saido TC; Michikawa M; Taru H; Sobu Y; Hata S; Nakaya T; Suzuki T
    Neurobiol Aging; 2023 Mar; 123():63-74. PubMed ID: 36638682
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Apolipoprotein E and oxidative stress in brain with relevance to Alzheimer's disease.
    Butterfield DA; Mattson MP
    Neurobiol Dis; 2020 May; 138():104795. PubMed ID: 32036033
    [TBL] [Abstract][Full Text] [Related]  

  • 12. APOE modulates the effect of estrogen therapy on Aβ accumulation EFAD-Tg mice.
    Kunzler J; Youmans KL; Yu C; Ladu MJ; Tai LM
    Neurosci Lett; 2014 Feb; 560():131-6. PubMed ID: 24368217
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Apolipoprotein E2 Expression Alters Endosomal Pathways in a Mouse Model With Increased Brain Exosome Levels During Aging.
    Peng KY; Liemisa B; Pasato J; D'Acunzo P; Pawlik M; Heguy A; Penikalapati SC; Labuza A; Pidikiti H; Alldred MJ; Ginsberg SD; Levy E; Mathews PM
    Traffic; 2024 May; 25(5):e12937. PubMed ID: 38777335
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Human Apolipoprotein E Genotype Differentially Affects Olfactory Behavior and Sensory Physiology in Mice.
    East BS; Fleming G; Peng K; Olofsson JK; Levy E; Mathews PM; Wilson DA
    Neuroscience; 2018 Jun; 380():103-110. PubMed ID: 29678753
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Total apolipoprotein E levels and specific isoform composition in cerebrospinal fluid and plasma from Alzheimer's disease patients and controls.
    Martínez-Morillo E; Hansson O; Atagi Y; Bu G; Minthon L; Diamandis EP; Nielsen HM
    Acta Neuropathol; 2014 May; 127(5):633-43. PubMed ID: 24633805
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A multi-hit hypothesis for an APOE4-dependent pathophysiological state.
    Steele OG; Stuart AC; Minkley L; Shaw K; Bonnar O; Anderle S; Penn AC; Rusted J; Serpell L; Hall C; King S
    Eur J Neurosci; 2022 Nov; 56(9):5476-5515. PubMed ID: 35510513
    [TBL] [Abstract][Full Text] [Related]  

  • 17. APOE effects on regional tau in preclinical Alzheimer's disease.
    Young CB; Johns E; Kennedy G; Belloy ME; Insel PS; Greicius MD; Sperling RA; Johnson KA; Poston KL; Mormino EC; ;
    Mol Neurodegener; 2023 Jan; 18(1):1. PubMed ID: 36597122
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Intracerebral Expression of AAV-APOE4 Is Not Sufficient to Alter Tau Burden in Two Distinct Models of Tauopathy.
    Koller EJ; Gonzalez De La Cruz E; Weinrich M; Williams T; Cruz PE; Ryu D; Golde TE; Sullivan PM; Lewis J; Borchelt DR; Chakrabarty P
    Mol Neurobiol; 2020 Apr; 57(4):1986-2001. PubMed ID: 31903524
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Effect of Chronic Cadmium Exposure on Brain and Liver Transporters and Drug-Metabolizing Enzymes in Male and Female Mice Genetically Predisposed to Alzheimer's Disease.
    Wang H; Zhang L; Xia Z; Cui JY
    Drug Metab Dispos; 2022 Oct; 50(10):1414-1428. PubMed ID: 35878927
    [TBL] [Abstract][Full Text] [Related]  

  • 20. APOE genotype alters glial activation and loss of synaptic markers in mice.
    Zhu Y; Nwabuisi-Heath E; Dumanis SB; Tai LM; Yu C; Rebeck GW; LaDu MJ
    Glia; 2012 Apr; 60(4):559-69. PubMed ID: 22228589
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.