BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

502 related articles for article (PubMed ID: 37348157)

  • 1. Development of KEAP1-targeting PROTAC and its antioxidant properties: In vitro and in vivo.
    Park SY; Gurung R; Hwang JH; Kang JH; Jung HJ; Zeb A; Hwang JI; Park SJ; Maeng HJ; Shin D; Oh SH
    Redox Biol; 2023 Aug; 64():102783. PubMed ID: 37348157
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design and characterization of a heterobifunctional degrader of KEAP1.
    Chen H; Nguyen NH; Magtoto CM; Cobbold SA; Bidgood GM; Meza Guzman LG; Richardson LW; Corbin J; Au AE; Lechtenberg BC; Feltham R; Sutherland KD; Grohmann C; Nicholson SE; Sleebs BE
    Redox Biol; 2023 Feb; 59():102552. PubMed ID: 36473314
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Caffeic acid prevents acetaminophen-induced liver injury by activating the Keap1-Nrf2 antioxidative defense system.
    Pang C; Zheng Z; Shi L; Sheng Y; Wei H; Wang Z; Ji L
    Free Radic Biol Med; 2016 Feb; 91():236-46. PubMed ID: 26721592
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Sika deer antler protein against acetaminophen-induced oxidative stress and apoptosis in HK-2 cells via activating Nrf2/keap1/HO-1 pathway.
    Ruan H; Wang L; Wang J; Sun H; He X; Li W; Zhang J
    J Food Biochem; 2019 Dec; 43(12):e13067. PubMed ID: 31599006
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A bioactive ligand-conjugated iridium(III) metal-based complex as a Keap1-Nrf2 protein-protein interaction inhibitor against acetaminophen-induced acute liver injury.
    Li G; Liu H; Feng R; Kang TS; Wang W; Ko CN; Wong CY; Ye M; Ma DL; Wan JB; Leung CH
    Redox Biol; 2021 Dec; 48():102129. PubMed ID: 34526248
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Targeting the KEAP1-NRF2 System to Prevent Kidney Disease Progression.
    Nezu M; Suzuki N; Yamamoto M
    Am J Nephrol; 2017; 45(6):473-483. PubMed ID: 28502971
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The hypertension drug, verapamil, activates Nrf2 by promoting p62-dependent autophagic Keap1 degradation and prevents acetaminophen-induced cytotoxicity.
    Lee DH; Park JS; Lee YS; Sung SH; Lee YH; Bae SH
    BMB Rep; 2017 Feb; 50(2):91-96. PubMed ID: 27998394
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Tetrahydrocurcumin and octahydrocurcumin, the primary and final hydrogenated metabolites of curcumin, possess superior hepatic-protective effect against acetaminophen-induced liver injury: Role of CYP2E1 and Keap1-Nrf2 pathway.
    Luo DD; Chen JF; Liu JJ; Xie JH; Zhang ZB; Gu JY; Zhuo JY; Huang S; Su ZR; Sun ZH
    Food Chem Toxicol; 2019 Jan; 123():349-362. PubMed ID: 30423402
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The stress response protein REDD1 promotes diabetes-induced oxidative stress in the retina by Keap1-independent Nrf2 degradation.
    Miller WP; Sunilkumar S; Giordano JF; Toro AL; Barber AJ; Dennis MD
    J Biol Chem; 2020 May; 295(21):7350-7361. PubMed ID: 32295843
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Activation of p62-keap1-Nrf2 antioxidant pathway in the early stage of acetaminophen-induced acute liver injury in mice.
    Shen Z; Wang Y; Su Z; Kou R; Xie K; Song F
    Chem Biol Interact; 2018 Feb; 282():22-28. PubMed ID: 29331651
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Enhanced Keap1-Nrf2/Trx-1 axis by daphnetin protects against oxidative stress-driven hepatotoxicity via inhibiting ASK1/JNK and Txnip/NLRP3 inflammasome activation.
    Lv H; Zhu C; Wei W; Lv X; Yu Q; Deng X; Ci X
    Phytomedicine; 2020 Jun; 71():153241. PubMed ID: 32454347
    [TBL] [Abstract][Full Text] [Related]  

  • 12. NRF2 activation by reversible KEAP1 binding induces the antioxidant response in primary neurons and astrocytes of a Huntington's disease mouse model.
    Moretti D; Tambone S; Cerretani M; Fezzardi P; Missineo A; Sherman LT; Munoz-Sajuan I; Harper S; Dominquez C; Pacifici R; Tomei L; Park L; Bresciani A
    Free Radic Biol Med; 2021 Jan; 162():243-254. PubMed ID: 33096251
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Phytochemical composition, isolation and hepatoprotective activity of active fraction from Veronica ciliata against acetaminophen-induced acute liver injury via p62-Keap1-Nrf2 signaling pathway.
    Lu Q; Tan S; Gu W; Li F; Hua W; Zhang S; Chen F; Tang L
    J Ethnopharmacol; 2019 Oct; 243():112089. PubMed ID: 31310828
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Directly interact with Keap1 and LPS is involved in the anti-inflammatory mechanisms of (-)-epicatechin-3-gallate in LPS-induced macrophages and endotoxemia.
    Chiou YS; Huang Q; Ho CT; Wang YJ; Pan MH
    Free Radic Biol Med; 2016 May; 94():1-16. PubMed ID: 26878775
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Activation of KEAP1/NRF2 stress signaling involved in the molecular basis of hemin-induced cytotoxicity in human pro-erythroid K562 cells.
    Georgiou-Siafis SK; Tsiftsoglou AS
    Biochem Pharmacol; 2020 May; 175():113900. PubMed ID: 32156661
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Discovery of NAFLD-Improving Agents by Promoting the Degradation of Keap1.
    Qi M; Zhong H; Cheng Z; Chen S; Xiao H; Shang J; Chen L; Sun J
    J Med Chem; 2023 Jul; 66(13):9184-9200. PubMed ID: 37386884
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Acetyl-l-carnitine prevents homocysteine-induced suppression of Nrf2/Keap1 mediated antioxidation in human lens epithelial cells.
    Yang SP; Yang XZ; Cao GP
    Mol Med Rep; 2015 Jul; 12(1):1145-50. PubMed ID: 25776802
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Identification of an adaptor protein that facilitates Nrf2-Keap1 complex formation and modulates antioxidant response.
    Zhang Y; Hou Y; Liu C; Li Y; Guo W; Wu JL; Xu D; You X; Pan Y; Chen Y
    Free Radic Biol Med; 2016 Aug; 97():38-49. PubMed ID: 27212020
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Sarmentosin promotes USP17 and regulates Nrf2-mediated mitophagy and cellular oxidative stress to alleviate APAP-induced acute liver failure.
    Jiang Z; Yang X; Han Y; Li J; Hu C; Liu C; Xiao W
    Phytomedicine; 2022 Sep; 104():154337. PubMed ID: 35849971
    [TBL] [Abstract][Full Text] [Related]  

  • 20. NF-κB and Keap1 Interaction Represses Nrf2-Mediated Antioxidant Response in Rabbit Hemorrhagic Disease Virus Infection.
    Hu B; Wei H; Song Y; Chen M; Fan Z; Qiu R; Zhu W; Xu W; Wang F
    J Virol; 2020 May; 94(10):. PubMed ID: 32161178
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 26.