154 related articles for article (PubMed ID: 37349114)
21. Metformin suppresses pregnane X receptor (PXR)-regulated transactivation of CYP3A4 gene.
Krausova L; Stejskalova L; Wang H; Vrzal R; Dvorak Z; Mani S; Pavek P
Biochem Pharmacol; 2011 Dec; 82(11):1771-80. PubMed ID: 21920351
[TBL] [Abstract][Full Text] [Related]
22. Activation of the aryl hydrocarbon receptor decreases rifampicin-induced CYP3A4 expression in primary human hepatocytes and HepaRG.
Rasmussen MK; Daujat-Chavanieu M; Gerbal-Chaloin S
Toxicol Lett; 2017 Aug; 277():1-8. PubMed ID: 28571685
[TBL] [Abstract][Full Text] [Related]
23. Inhibition of CYP3A4 expression by ketoconazole is mediated by the disruption of pregnane X receptor, steroid receptor coactivator-1, and hepatocyte nuclear factor 4alpha interaction.
Lim YP; Kuo SC; Lai ML; Huang JD
Pharmacogenet Genomics; 2009 Jan; 19(1):11-24. PubMed ID: 19077665
[TBL] [Abstract][Full Text] [Related]
24. Intestinal human colon adenocarcinoma cell line LS180 is an excellent model to study pregnane X receptor, but not constitutive androstane receptor, mediated CYP3A4 and multidrug resistance transporter 1 induction: studies with anti-human immunodeficiency virus protease inhibitors.
Gupta A; Mugundu GM; Desai PB; Thummel KE; Unadkat JD
Drug Metab Dispos; 2008 Jun; 36(6):1172-80. PubMed ID: 18332086
[TBL] [Abstract][Full Text] [Related]
25. Pregnane X receptor polymorphism affects CYP3A4 induction via a ligand-dependent interaction with steroid receptor coactivator-1.
Lim YP; Huang JD
Pharmacogenet Genomics; 2007 May; 17(5):369-82. PubMed ID: 17429319
[TBL] [Abstract][Full Text] [Related]
26. PXR-mediated transcriptional activation of CYP3A4 by cryptotanshinone and tanshinone IIA.
Yu C; Ye S; Sun H; Liu Y; Gao L; Shen C; Chen S; Zeng S
Chem Biol Interact; 2009 Jan; 177(1):58-64. PubMed ID: 18805405
[TBL] [Abstract][Full Text] [Related]
27. Regulation of CYP3A4 by pregnane X receptor: The role of nuclear receptors competing for response element binding.
Istrate MA; Nussler AK; Eichelbaum M; Burk O
Biochem Biophys Res Commun; 2010 Mar; 393(4):688-93. PubMed ID: 20171174
[TBL] [Abstract][Full Text] [Related]
28. Role of human pregnane X receptor in tamoxifen- and 4-hydroxytamoxifen-mediated CYP3A4 induction in primary human hepatocytes and LS174T cells.
Sane RS; Buckley DJ; Buckley AR; Nallani SC; Desai PB
Drug Metab Dispos; 2008 May; 36(5):946-54. PubMed ID: 18299335
[TBL] [Abstract][Full Text] [Related]
29. Indirect activation of pregnane X receptor in the induction of hepatic CYP3A11 by high-dose rifampicin in mice.
Yamasaki Y; Kobayashi K; Inaba A; Uehara D; Tojima H; Kakizaki S; Chiba K
Xenobiotica; 2018 Nov; 48(11):1098-1105. PubMed ID: 29095659
[TBL] [Abstract][Full Text] [Related]
30. Effects of atorvastatin metabolites on induction of drug-metabolizing enzymes and membrane transporters through human pregnane X receptor.
Hoffart E; Ghebreghiorghis L; Nussler AK; Thasler WE; Weiss TS; Schwab M; Burk O
Br J Pharmacol; 2012 Mar; 165(5):1595-608. PubMed ID: 21913896
[TBL] [Abstract][Full Text] [Related]
31. Functional characterization of four naturally occurring variants of human pregnane X receptor (PXR): one variant causes dramatic loss of both DNA binding activity and the transactivation of the CYP3A4 promoter/enhancer region.
Koyano S; Kurose K; Saito Y; Ozawa S; Hasegawa R; Komamura K; Ueno K; Kamakura S; Kitakaze M; Nakajima T; Matsumoto K; Akasawa A; Saito H; Sawada J
Drug Metab Dispos; 2004 Jan; 32(1):149-54. PubMed ID: 14709632
[TBL] [Abstract][Full Text] [Related]
32. Induced CYP3A4 expression in confluent Huh7 hepatoma cells as a result of decreased cell proliferation and subsequent pregnane X receptor activation.
Sivertsson L; Edebert I; Palmertz MP; Ingelman-Sundberg M; Neve EP
Mol Pharmacol; 2013 Mar; 83(3):659-70. PubMed ID: 23264496
[TBL] [Abstract][Full Text] [Related]
33. U0126, a mitogen-activated protein kinase kinase 1 and 2 (MEK1 and 2) inhibitor, selectively up-regulates main isoforms of CYP3A subfamily via a pregnane X receptor (PXR) in HepG2 cells.
Smutny T; Bitman M; Urban M; Dubecka M; Vrzal R; Dvorak Z; Pavek P
Arch Toxicol; 2014 Dec; 88(12):2243-59. PubMed ID: 24819614
[TBL] [Abstract][Full Text] [Related]
34. Paraspeckles modulate the intranuclear distribution of paraspeckle-associated Ctn RNA.
Anantharaman A; Jadaliha M; Tripathi V; Nakagawa S; Hirose T; Jantsch MF; Prasanth SG; Prasanth KV
Sci Rep; 2016 Sep; 6():34043. PubMed ID: 27665741
[TBL] [Abstract][Full Text] [Related]
35. Rifampicin-activated human pregnane X receptor and CYP3A4 induction enhance acetaminophen-induced toxicity.
Cheng J; Ma X; Krausz KW; Idle JR; Gonzalez FJ
Drug Metab Dispos; 2009 Aug; 37(8):1611-21. PubMed ID: 19460945
[TBL] [Abstract][Full Text] [Related]
36. Differential regulation of CYP3A4 promoter activity by a new class of natural product derivatives binding to pregnane X receptor.
Banerjee M; Chen T
Biochem Pharmacol; 2013 Sep; 86(6):824-35. PubMed ID: 23928187
[TBL] [Abstract][Full Text] [Related]
37. PXR/CYP3A4-humanized mice for studying drug-drug interactions involving intestinal P-glycoprotein.
Holmstock N; Gonzalez FJ; Baes M; Annaert P; Augustijns P
Mol Pharm; 2013 Mar; 10(3):1056-62. PubMed ID: 23360470
[TBL] [Abstract][Full Text] [Related]
38. The far and distal enhancers in the CYP3A4 gene co-ordinate the proximal promoter in responding similarly to the pregnane X receptor but differentially to hepatocyte nuclear factor-4alpha.
Liu FJ; Song X; Yang D; Deng R; Yan B
Biochem J; 2008 Jan; 409(1):243-50. PubMed ID: 17764444
[TBL] [Abstract][Full Text] [Related]
39. The pregnane X receptor regulates gene expression in a ligand- and promoter-selective fashion.
Masuyama H; Suwaki N; Tateishi Y; Nakatsukasa H; Segawa T; Hiramatsu Y
Mol Endocrinol; 2005 May; 19(5):1170-80. PubMed ID: 15650019
[TBL] [Abstract][Full Text] [Related]
40. Effect of panaxytriol on cytochrome P450 3A4 via the pregnane X receptor regulatory pathway.
Wu J; Yao N; Hu Q; Liu M; Zhang H; Xiong Y; Hu J; Xia C
Phytother Res; 2019 Apr; 33(4):968-975. PubMed ID: 30653754
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
