193 related articles for article (PubMed ID: 37353565)
21. Smad ubiquitylation regulatory factor 1/2 (Smurf1/2) promotes p53 degradation by stabilizing the E3 ligase MDM2.
Nie J; Xie P; Liu L; Xing G; Chang Z; Yin Y; Tian C; He F; Zhang L
J Biol Chem; 2010 Jul; 285(30):22818-30. PubMed ID: 20484049
[TBL] [Abstract][Full Text] [Related]
22. Axotrophin/MARCH7 acts as an E3 ubiquitin ligase and ubiquitinates tau protein in vitro impairing microtubule binding.
Flach K; Ramminger E; Hilbrich I; Arsalan-Werner A; Albrecht F; Herrmann L; Goedert M; Arendt T; Holzer M
Biochim Biophys Acta; 2014 Sep; 1842(9):1527-38. PubMed ID: 24905733
[TBL] [Abstract][Full Text] [Related]
23. Escape, or Vanish: Control the Fate of p53 through MDM2-Mediated Ubiquitination.
Wei J; Yang Y; Lu M; Xu L; Liu F; Yuan Z; Bao Q; Jiang Z; Xu X; Guo X; Zhang X; You Q; Sun H
Anticancer Agents Med Chem; 2015; 16(2):174-89. PubMed ID: 26343143
[TBL] [Abstract][Full Text] [Related]
24. Competitive ubiquitination activates the tumor suppressor p53.
Li X; Guo M; Cai L; Du T; Liu Y; Ding HF; Wang H; Zhang J; Chen X; Yan C
Cell Death Differ; 2020 Jun; 27(6):1807-1818. PubMed ID: 31796886
[TBL] [Abstract][Full Text] [Related]
25. Functional analysis and consequences of Mdm2 E3 ligase inhibition in human tumor cells.
Wade M; Li YC; Matani AS; Braun SM; Milanesi F; Rodewald LW; Wahl GM
Oncogene; 2012 Nov; 31(45):4789-97. PubMed ID: 22266850
[TBL] [Abstract][Full Text] [Related]
26. TRIAD1 is negatively regulated by the MDM2 E3 ligase.
Bae S; Jung JH; An IS; Kim OY; Lee MJ; Lee JH; Park IC; Lee SJ; An S
Oncol Rep; 2012 Nov; 28(5):1924-8. PubMed ID: 22940738
[TBL] [Abstract][Full Text] [Related]
27. Inactivation of the MDM2 RING domain enhances p53 transcriptional activity in mice.
Tian H; Tackmann NR; Jin A; Zheng J; Zhang Y
J Biol Chem; 2017 Dec; 292(52):21614-21622. PubMed ID: 29123033
[TBL] [Abstract][Full Text] [Related]
28. P53 mRNA controls p53 activity by managing Mdm2 functions.
Candeias MM; Malbert-Colas L; Powell DJ; Daskalogianni C; Maslon MM; Naski N; Bourougaa K; Calvo F; Fåhraeus R
Nat Cell Biol; 2008 Sep; 10(9):1098-105. PubMed ID: 19160491
[TBL] [Abstract][Full Text] [Related]
29. Critical contribution of the MDM2 acidic domain to p53 ubiquitination.
Kawai H; Wiederschain D; Yuan ZM
Mol Cell Biol; 2003 Jul; 23(14):4939-47. PubMed ID: 12832479
[TBL] [Abstract][Full Text] [Related]
30. Mdmx enhances p53 ubiquitination by altering the substrate preference of the Mdm2 ubiquitin ligase.
Okamoto K; Taya Y; Nakagama H
FEBS Lett; 2009 Sep; 583(17):2710-4. PubMed ID: 19619542
[TBL] [Abstract][Full Text] [Related]
31. MDM2-mediated degradation of WRN promotes cellular senescence in a p53-independent manner.
Liu B; Yi J; Yang X; Liu L; Lou X; Zhang Z; Qi H; Wang Z; Zou J; Zhu WG; Gu W; Luo J
Oncogene; 2019 Apr; 38(14):2501-2515. PubMed ID: 30532073
[TBL] [Abstract][Full Text] [Related]
32. Regulation of the MDM2-p53 pathway by ribosomal protein L11 involves a post-ubiquitination mechanism.
Dai MS; Shi D; Jin Y; Sun XX; Zhang Y; Grossman SR; Lu H
J Biol Chem; 2006 Aug; 281(34):24304-13. PubMed ID: 16803902
[TBL] [Abstract][Full Text] [Related]
33. MDM2 protein-mediated ubiquitination of numb protein: identification of a second physiological substrate of MDM2 that employs a dual-site docking mechanism.
Sczaniecka M; Gladstone K; Pettersson S; McLaren L; Huart AS; Wallace M
J Biol Chem; 2012 Apr; 287(17):14052-68. PubMed ID: 22337874
[TBL] [Abstract][Full Text] [Related]
34. Epstein-Barr virus nuclear antigen 3C augments Mdm2-mediated p53 ubiquitination and degradation by deubiquitinating Mdm2.
Saha A; Murakami M; Kumar P; Bajaj B; Sims K; Robertson ES
J Virol; 2009 May; 83(9):4652-69. PubMed ID: 19244339
[TBL] [Abstract][Full Text] [Related]
35. Phosphomimetic mutation of the N-terminal lid of MDM2 enhances the polyubiquitination of p53 through stimulation of E2-ubiquitin thioester hydrolysis.
Fraser JA; Worrall EG; Lin Y; Landre V; Pettersson S; Blackburn E; Walkinshaw M; Muller P; Vojtesek B; Ball K; Hupp TR
J Mol Biol; 2015 Apr; 427(8):1728-47. PubMed ID: 25543083
[TBL] [Abstract][Full Text] [Related]
36. p53 regulation: teamwork between RING domains of Mdm2 and MdmX.
Wang X
Cell Cycle; 2011 Dec; 10(24):4225-9. PubMed ID: 22134240
[TBL] [Abstract][Full Text] [Related]
37. Association of p19(ARF) with Mdm2 inhibits ubiquitin ligase activity of Mdm2 for tumor suppressor p53.
Honda R; Yasuda H
EMBO J; 1999 Jan; 18(1):22-7. PubMed ID: 9878046
[TBL] [Abstract][Full Text] [Related]
38. The RNA binding protein RALY suppresses p53 activity and promotes lung tumorigenesis.
Hu H; Zhao K; Fang D; Wang Z; Yu N; Yao B; Liu K; Wang F; Mei Y
Cell Rep; 2023 Apr; 42(4):112288. PubMed ID: 36952348
[TBL] [Abstract][Full Text] [Related]
39. Regulation of p53 by Mdm2 E3 ligase function is dispensable in embryogenesis and development, but essential in response to DNA damage.
Tollini LA; Jin A; Park J; Zhang Y
Cancer Cell; 2014 Aug; 26(2):235-47. PubMed ID: 25117711
[TBL] [Abstract][Full Text] [Related]
40. Hetero-oligomerization with MdmX rescues the ubiquitin/Nedd8 ligase activity of RING finger mutants of Mdm2.
Singh RK; Iyappan S; Scheffner M
J Biol Chem; 2007 Apr; 282(15):10901-7. PubMed ID: 17301054
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
