307 related articles for article (PubMed ID: 37355492)
1. APP-BACE1 Interaction and Intracellular Localization Regulate Aβ Production in iPSC-Derived Cortical Neurons.
Roselli S; Satir TM; Camacho R; Fruhwürth S; Bergström P; Zetterberg H; Agholme L
Cell Mol Neurobiol; 2023 Oct; 43(7):3653-3668. PubMed ID: 37355492
[TBL] [Abstract][Full Text] [Related]
2. Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis.
Deng Y; Wang Z; Wang R; Zhang X; Zhang S; Wu Y; Staufenbiel M; Cai F; Song W
Eur J Neurosci; 2013 Jun; 37(12):1962-9. PubMed ID: 23773065
[TBL] [Abstract][Full Text] [Related]
3. Cholesterol-lowering drugs reduce APP processing to Aβ by inducing APP dimerization.
Langness VF; van der Kant R; Das U; Wang L; Chaves RDS; Goldstein LSB
Mol Biol Cell; 2021 Feb; 32(3):247-259. PubMed ID: 33296223
[TBL] [Abstract][Full Text] [Related]
4. The neuronal-specific isoform of BIN1 regulates β-secretase cleavage of APP and Aβ generation in a RIN3-dependent manner.
Bhattacharyya R; Teves CAF; Long A; Hofert M; Tanzi RE
Sci Rep; 2022 Mar; 12(1):3486. PubMed ID: 35241726
[TBL] [Abstract][Full Text] [Related]
5. Beta-secretase/BACE1 promotes APP endocytosis and processing in the endosomes and on cell membrane.
Wang M; Jing T; Wang X; Yao D
Neurosci Lett; 2018 Oct; 685():63-67. PubMed ID: 30120949
[TBL] [Abstract][Full Text] [Related]
6. Enhanced cleavage of APP by co-expressed Bace1 alters the distribution of APP and its fragments in neuronal and non-neuronal cells.
Aow J; Huang TR; Thinakaran G; Koo EH
Mol Neurobiol; 2022 May; 59(5):3073-3090. PubMed ID: 35266114
[TBL] [Abstract][Full Text] [Related]
7. Decrease in brain soluble amyloid precursor protein β (sAPPβ) in Alzheimer's disease cortex.
Wu G; Sankaranarayanan S; Hsieh SH; Simon AJ; Savage MJ
J Neurosci Res; 2011 Jun; 89(6):822-32. PubMed ID: 21433051
[TBL] [Abstract][Full Text] [Related]
8. Suppression of amyloid-β secretion from neurons by cis-9, trans-11-octadecadienoic acid, an isomer of conjugated linoleic acid.
Hata S; Kano K; Kikuchi K; Kinoshita S; Sobu Y; Saito H; Saito T; Saido TC; Sano Y; Taru H; Aoki J; Komano H; Tomita T; Natori S; Suzuki T
J Neurochem; 2021 Nov; 159(3):603-617. PubMed ID: 34379812
[TBL] [Abstract][Full Text] [Related]
9. BACE1: the beta-secretase enzyme in Alzheimer's disease.
Vassar R
J Mol Neurosci; 2004; 23(1-2):105-14. PubMed ID: 15126696
[TBL] [Abstract][Full Text] [Related]
10. The contribution of activated astrocytes to Aβ production: implications for Alzheimer's disease pathogenesis.
Zhao J; O'Connor T; Vassar R
J Neuroinflammation; 2011 Nov; 8():150. PubMed ID: 22047170
[TBL] [Abstract][Full Text] [Related]
11. Mitochondria are devoid of amyloid β-protein (Aβ)-producing secretases: Evidence for unlikely occurrence within mitochondria of Aβ generation from amyloid precursor protein.
Mamada N; Tanokashira D; Ishii K; Tamaoka A; Araki W
Biochem Biophys Res Commun; 2017 Apr; 486(2):321-328. PubMed ID: 28302486
[TBL] [Abstract][Full Text] [Related]
12. Alternative Selection of β-Site APP-Cleaving Enzyme 1 (BACE1) Cleavage Sites in Amyloid β-Protein Precursor (APP) Harboring Protective and Pathogenic Mutations within the Aβ Sequence.
Kimura A; Hata S; Suzuki T
J Biol Chem; 2016 Nov; 291(46):24041-24053. PubMed ID: 27687728
[TBL] [Abstract][Full Text] [Related]
13. Reduction of the expression of the late-onset Alzheimer's disease (AD) risk-factor
Andrew RJ; De Rossi P; Nguyen P; Kowalski HR; Recupero AJ; Guerbette T; Krause SV; Rice RC; Laury-Kleintop L; Wagner SL; Thinakaran G
J Biol Chem; 2019 Mar; 294(12):4477-4487. PubMed ID: 30692199
[TBL] [Abstract][Full Text] [Related]
14. The beta-secretase, BACE: a prime drug target for Alzheimer's disease.
Vassar R
J Mol Neurosci; 2001 Oct; 17(2):157-70. PubMed ID: 11816789
[TBL] [Abstract][Full Text] [Related]
15. Molecular mechanisms of Alzheimer disease protection by the A673T allele of amyloid precursor protein.
Maloney JA; Bainbridge T; Gustafson A; Zhang S; Kyauk R; Steiner P; van der Brug M; Liu Y; Ernst JA; Watts RJ; Atwal JK
J Biol Chem; 2014 Nov; 289(45):30990-1000. PubMed ID: 25253696
[TBL] [Abstract][Full Text] [Related]
16. A Large Panel of Isogenic APP and PSEN1 Mutant Human iPSC Neurons Reveals Shared Endosomal Abnormalities Mediated by APP β-CTFs, Not Aβ.
Kwart D; Gregg A; Scheckel C; Murphy EA; Paquet D; Duffield M; Fak J; Olsen O; Darnell RB; Tessier-Lavigne M
Neuron; 2019 Oct; 104(2):256-270.e5. PubMed ID: 31416668
[TBL] [Abstract][Full Text] [Related]
17. Sorting nexin 12 interacts with BACE1 and regulates BACE1-mediated APP processing.
Zhao Y; Wang Y; Yang J; Wang X; Zhao Y; Zhang X; Zhang YW
Mol Neurodegener; 2012 Jun; 7():30. PubMed ID: 22709416
[TBL] [Abstract][Full Text] [Related]
18. Distinct transcriptional regulation and function of the human BACE2 and BACE1 genes.
Sun X; Wang Y; Qing H; Christensen MA; Liu Y; Zhou W; Tong Y; Xiao C; Huang Y; Zhang S; Liu X; Song W
FASEB J; 2005 May; 19(7):739-49. PubMed ID: 15857888
[TBL] [Abstract][Full Text] [Related]
19. BACE1 Cleavage Site Selection Critical for Amyloidogenesis and Alzheimer's Pathogenesis.
Zhang S; Wang Z; Cai F; Zhang M; Wu Y; Zhang J; Song W
J Neurosci; 2017 Jul; 37(29):6915-6925. PubMed ID: 28626014
[TBL] [Abstract][Full Text] [Related]
20. Regulation of Synaptic Amyloid-β Generation through BACE1 Retrograde Transport in a Mouse Model of Alzheimer's Disease.
Ye X; Feng T; Tammineni P; Chang Q; Jeong YY; Margolis DJ; Cai H; Kusnecov A; Cai Q
J Neurosci; 2017 Mar; 37(10):2639-2655. PubMed ID: 28159908
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
