194 related articles for article (PubMed ID: 37363915)
1. The chloride antiporter CLCN7 is a modifier of lysosome dysfunction in FIG4 and VAC14 mutants.
Cao X; Lenk GM; Mikusevic V; Mindell JA; Meisler MH
PLoS Genet; 2023 Jun; 19(6):e1010800. PubMed ID: 37363915
[TBL] [Abstract][Full Text] [Related]
2. Chloroquine corrects enlarged lysosomes in FIG4 null cells and reduces neurodegeneration in Fig4 null mice.
Lenk GM; Meisler MH
Mol Genet Metab; 2022 Dec; 137(4):382-387. PubMed ID: 36434903
[TBL] [Abstract][Full Text] [Related]
3. Protective role of the lipid phosphatase Fig4 in the adult nervous system.
Mironova YA; Lin JP; Kalinski AL; Huffman LD; Lenk GM; Havton LA; Meisler MH; Giger RJ
Hum Mol Genet; 2018 Jul; 27(14):2443-2453. PubMed ID: 29688489
[TBL] [Abstract][Full Text] [Related]
4. Altered phenotypes due to genetic interaction between the mouse phosphoinositide biosynthesis genes Fig4 and Pip4k2c.
Cao X; Lenk GM; Meisler MH
G3 (Bethesda); 2023 Aug; 13(8):. PubMed ID: 36691351
[TBL] [Abstract][Full Text] [Related]
5. FIG4 regulates lysosome membrane homeostasis independent of phosphatase function.
Bharadwaj R; Cunningham KM; Zhang K; Lloyd TE
Hum Mol Genet; 2016 Feb; 25(4):681-92. PubMed ID: 26662798
[TBL] [Abstract][Full Text] [Related]
6. Neuronal expression of Fig4 is both necessary and sufficient to prevent spongiform neurodegeneration.
Ferguson CJ; Lenk GM; Jones JM; Grant AE; Winters JJ; Dowling JJ; Giger RJ; Meisler MH
Hum Mol Genet; 2012 Aug; 21(16):3525-34. PubMed ID: 22581779
[TBL] [Abstract][Full Text] [Related]
7. Rescue of neurodegeneration in the Fig4 null mouse by a catalytically inactive FIG4 transgene.
Lenk GM; Frei CM; Miller AC; Wallen RC; Mironova YA; Giger RJ; Meisler MH
Hum Mol Genet; 2016 Jan; 25(2):340-7. PubMed ID: 26604144
[TBL] [Abstract][Full Text] [Related]
8. Yunis-Varón syndrome is caused by mutations in FIG4, encoding a phosphoinositide phosphatase.
Campeau PM; Lenk GM; Lu JT; Bae Y; Burrage L; Turnpenny P; Román Corona-Rivera J; Morandi L; Mora M; Reutter H; Vulto-van Silfhout AT; Faivre L; Haan E; Gibbs RA; Meisler MH; Lee BH
Am J Hum Genet; 2013 May; 92(5):781-91. PubMed ID: 23623387
[TBL] [Abstract][Full Text] [Related]
9. Congenital CNS hypomyelination in the Fig4 null mouse is rescued by neuronal expression of the PI(3,5)P(2) phosphatase Fig4.
Winters JJ; Ferguson CJ; Lenk GM; Giger-Mateeva VI; Shrager P; Meisler MH; Giger RJ
J Neurosci; 2011 Nov; 31(48):17736-51. PubMed ID: 22131434
[TBL] [Abstract][Full Text] [Related]
10. Cerebral hypomyelination associated with biallelic variants of FIG4.
Lenk GM; Berry IR; Stutterd CA; Blyth M; Green L; Vadlamani G; Warren D; Craven I; Fanjul-Fernandez M; Rodriguez-Casero V; Lockhart PJ; Vanderver A; Simons C; Gibb S; Sadedin S; ; White SM; Christodoulou J; Skibina O; Ruddle J; Tan TY; Leventer RJ; Livingston JH; Meisler MH
Hum Mutat; 2019 May; 40(5):619-630. PubMed ID: 30740813
[TBL] [Abstract][Full Text] [Related]
11. Vacuole size control: regulation of PtdIns(3,5)P2 levels by the vacuole-associated Vac14-Fig4 complex, a PtdIns(3,5)P2-specific phosphatase.
Rudge SA; Anderson DM; Emr SD
Mol Biol Cell; 2004 Jan; 15(1):24-36. PubMed ID: 14528018
[TBL] [Abstract][Full Text] [Related]
12. Roles for a lipid phosphatase in the activation of its opposing lipid kinase.
Strunk BS; Steinfeld N; Lee S; Jin N; Muñoz-Rivera C; Meeks G; Thomas A; Akemann C; Mapp AK; MacGurn JA; Weisman LS
Mol Biol Cell; 2020 Aug; 31(17):1835-1845. PubMed ID: 32583743
[TBL] [Abstract][Full Text] [Related]
13. Pathogenic mechanism of the FIG4 mutation responsible for Charcot-Marie-Tooth disease CMT4J.
Lenk GM; Ferguson CJ; Chow CY; Jin N; Jones JM; Grant AE; Zolov SN; Winters JJ; Giger RJ; Dowling JJ; Weisman LS; Meisler MH
PLoS Genet; 2011 Jun; 7(6):e1002104. PubMed ID: 21655088
[TBL] [Abstract][Full Text] [Related]
14. Reactivation of Lysosomal Ca2+ Efflux Rescues Abnormal Lysosomal Storage in FIG4-Deficient Cells.
Zou J; Hu B; Arpag S; Yan Q; Hamilton A; Zeng YS; Vanoye CG; Li J
J Neurosci; 2015 Apr; 35(17):6801-12. PubMed ID: 25926456
[TBL] [Abstract][Full Text] [Related]
15. Role of the phosphoinositide phosphatase FIG4 gene in familial epilepsy with polymicrogyria.
Baulac S; Lenk GM; Dufresnois B; Ouled Amar Bencheikh B; Couarch P; Renard J; Larson PA; Ferguson CJ; Noé E; Poirier K; Hubans C; Ferreira S; Guerrini R; Ouazzani R; El Hachimi KH; Meisler MH; Leguern E
Neurology; 2014 Mar; 82(12):1068-75. PubMed ID: 24598713
[TBL] [Abstract][Full Text] [Related]
16. Novel FIG4 mutations in Yunis-Varon syndrome.
Nakajima J; Okamoto N; Shiraishi J; Nishimura G; Nakashima M; Tsurusaki Y; Saitsu H; Kawashima H; Matsumoto N; Miyake N
J Hum Genet; 2013 Dec; 58(12):822-4. PubMed ID: 24088667
[TBL] [Abstract][Full Text] [Related]
17. FIG4 mutations leading to parkinsonism and a phenotypical continuum between CMT4J and Yunis Varón syndrome.
Zimmermann M; Schuster S; Boesch S; Korenke GC; Mohr J; Reichbauer J; Kernstock C; Kotzot D; Spahlinger V; Schüle-Freyer R; Schöls L
Parkinsonism Relat Disord; 2020 May; 74():6-11. PubMed ID: 32268254
[TBL] [Abstract][Full Text] [Related]
18. Insights into Lysosomal PI(3,5)P
Lees JA; Li P; Kumar N; Weisman LS; Reinisch KM
Mol Cell; 2020 Nov; 80(4):736-743.e4. PubMed ID: 33098764
[TBL] [Abstract][Full Text] [Related]
19. AAV9-mediated FIG4 delivery prolongs life span in Charcot-Marie-Tooth disease type 4J mouse model.
Presa M; Bailey RM; Davis C; Murphy T; Cook J; Walls R; Wilpan H; Bogdanik L; Lenk GM; Burgess RW; Gray SJ; Lutz C
J Clin Invest; 2021 Jun; 131(11):. PubMed ID: 33878035
[TBL] [Abstract][Full Text] [Related]
20. Mouse models of PI(3,5)P2 deficiency with impaired lysosome function.
Lenk GM; Meisler MH
Methods Enzymol; 2014; 534():245-60. PubMed ID: 24359958
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
