158 related articles for article (PubMed ID: 37364415)
1. Scaffold hopping derived novel benzoxazepinone RIPK1 inhibitors as anti-necroptosis agents.
Tang J; Wu Y; Zhao W; Qu Z; Yu J; Wang Z; Shi Y
Bioorg Med Chem; 2023 Aug; 91():117385. PubMed ID: 37364415
[TBL] [Abstract][Full Text] [Related]
2. Identification of the Raf kinase inhibitor TAK-632 and its analogues as potent inhibitors of necroptosis by targeting RIPK1 and RIPK3.
Chen X; Zhuang C; Ren Y; Zhang H; Qin X; Hu L; Fu J; Miao Z; Chai Y; Liu ZG; Zhang H; Cai Z; Wang HY
Br J Pharmacol; 2019 Jun; 176(12):2095-2108. PubMed ID: 30825190
[TBL] [Abstract][Full Text] [Related]
3. Discovery of novel biaryl benzoxazepinones as dual-mode receptor-interacting protein kinase-1 (RIPK1) inhibitors.
Xin Y; Dai P; Shao H; Zhuang C; Li J
Bioorg Med Chem; 2024 Feb; 100():117611. PubMed ID: 38309200
[TBL] [Abstract][Full Text] [Related]
4. Scaffold hopping derived novel benzoxazepinone receptor-interacting protein kinase 1 (RIP1) inhibitors as anti-necroptosis agents: Anti-inflammatory effect in systemic inflammatory response syndrome (SIRS) and epilepsy.
Jiang R; Xu B; Zhi S; Sun L; Yu B; Huang Q; Shi Y
Eur J Med Chem; 2024 Apr; 269():116304. PubMed ID: 38484677
[TBL] [Abstract][Full Text] [Related]
5. Inhibition of keratinocyte necroptosis mediated by RIPK1/RIPK3/MLKL provides a protective effect against psoriatic inflammation.
Duan X; Liu X; Liu N; Huang Y; Jin Z; Zhang S; Ming Z; Chen H
Cell Death Dis; 2020 Feb; 11(2):134. PubMed ID: 32075957
[TBL] [Abstract][Full Text] [Related]
6. Discovery of potent necroptosis inhibitors targeting RIPK1 kinase activity for the treatment of inflammatory disorder and cancer metastasis.
Hou J; Ju J; Zhang Z; Zhao C; Li Z; Zheng J; Sheng T; Zhang H; Hu L; Yu X; Zhang W; Li Y; Wu M; Ma H; Zhang X; He S
Cell Death Dis; 2019 Jun; 10(7):493. PubMed ID: 31235688
[TBL] [Abstract][Full Text] [Related]
7. Zinc finger protein 91 mediates necroptosis by initiating RIPK1-RIPK3-MLKL signal transduction in response to TNF receptor 1 ligation.
Zhong Y; Zhang ZH; Wang JY; Xing Y; Ri MH; Jin HL; Zuo HX; Li MY; Ma J; Jin X
Toxicol Lett; 2022 Mar; 356():75-88. PubMed ID: 34942311
[TBL] [Abstract][Full Text] [Related]
8. Ring closure strategy leads to potent RIPK3 inhibitors.
Wu S; Xu C; Xia K; Lin Y; Tian S; Ma H; Ji Y; Zhu F; He S; Zhang X
Eur J Med Chem; 2021 May; 217():113327. PubMed ID: 33730678
[TBL] [Abstract][Full Text] [Related]
9. RIPK1 counteracts ZBP1-mediated necroptosis to inhibit inflammation.
Lin J; Kumari S; Kim C; Van TM; Wachsmuth L; Polykratis A; Pasparakis M
Nature; 2016 Dec; 540(7631):124-128. PubMed ID: 27819681
[TBL] [Abstract][Full Text] [Related]
10. Profiling of the chemical space on the phenyl group of substituted benzothiazole RIPK3 inhibitors.
Xu Y; Liang C; Zhang W; Yu J; Xing C; Liu H; Zhuang C
Bioorg Chem; 2023 Feb; 131():106339. PubMed ID: 36599218
[TBL] [Abstract][Full Text] [Related]
11. Caspase-8, receptor-interacting protein kinase 1 (RIPK1), and RIPK3 regulate retinoic acid-induced cell differentiation and necroptosis.
Someda M; Kuroki S; Miyachi H; Tachibana M; Yonehara S
Cell Death Differ; 2020 May; 27(5):1539-1553. PubMed ID: 31659279
[TBL] [Abstract][Full Text] [Related]
12. Insight from Linker Investigations: Discovery of a Novel Phenylbenzothiazole Necroptosis Inhibitor Targeting Receptor-Interacting Protein Kinase 1 (RIPK1) from a Phenoxybenzothiazole Compound with Dual RIPK1/3 Targeting Activity.
Fang JJ; Yao HZ; Zhuang C; Chen FE
J Med Chem; 2023 Nov; 66(22):15288-15308. PubMed ID: 37917221
[TBL] [Abstract][Full Text] [Related]
13. Discovery of 4-amino-1,6-dihydro-7H-pyrrolo[2,3-d]pyridazin-7-one derivatives as potential receptor-interacting serine/threonine-protein kinase 1 (RIPK1) inhibitors.
Zhang C; Chen Y; Li Y; Shi N; Teng Y; Li N; Tang M; Ma Z; Deng D; Chen L
Eur J Med Chem; 2024 Feb; 265():116076. PubMed ID: 38171150
[TBL] [Abstract][Full Text] [Related]
14. Ligustroflavone reduces necroptosis in rat brain after ischemic stroke through targeting RIPK1/RIPK3/MLKL pathway.
Zhang YY; Liu WN; Li YQ; Zhang XJ; Yang J; Luo XJ; Peng J
Naunyn Schmiedebergs Arch Pharmacol; 2019 Sep; 392(9):1085-1095. PubMed ID: 31055628
[TBL] [Abstract][Full Text] [Related]
15. A cellular screen identifies ponatinib and pazopanib as inhibitors of necroptosis.
Fauster A; Rebsamen M; Huber KV; Bigenzahn JW; Stukalov A; Lardeau CH; Scorzoni S; Bruckner M; Gridling M; Parapatics K; Colinge J; Bennett KL; Kubicek S; Krautwald S; Linkermann A; Superti-Furga G
Cell Death Dis; 2015 May; 6(5):e1767. PubMed ID: 25996294
[TBL] [Abstract][Full Text] [Related]
16. FKBP12 mediates necroptosis by initiating RIPK1-RIPK3-MLKL signal transduction in response to TNF receptor 1 ligation.
Wang Z; Feng J; Yu J; Chen G
J Cell Sci; 2019 May; 132(10):. PubMed ID: 31028177
[TBL] [Abstract][Full Text] [Related]
17. Taurine attenuates valproic acid-induced hepatotoxicity via modulation of RIPK1/RIPK3/MLKL-mediated necroptosis signaling in mice.
Khodayar MJ; Kalantari H; Khorsandi L; Ahangar N; Samimi A; Alidadi H
Mol Biol Rep; 2021 May; 48(5):4153-4162. PubMed ID: 34032977
[TBL] [Abstract][Full Text] [Related]
18.
Zhang H; Xu L; Qin X; Chen X; Cong H; Hu L; Chen L; Miao Z; Zhang W; Cai Z; Zhuang C
J Med Chem; 2019 Jul; 62(14):6665-6681. PubMed ID: 31095385
[TBL] [Abstract][Full Text] [Related]
19. RIPK1 inhibits ZBP1-driven necroptosis during development.
Newton K; Wickliffe KE; Maltzman A; Dugger DL; Strasser A; Pham VC; Lill JR; Roose-Girma M; Warming S; Solon M; Ngu H; Webster JD; Dixit VM
Nature; 2016 Dec; 540(7631):129-133. PubMed ID: 27819682
[TBL] [Abstract][Full Text] [Related]
20. Key necroptotic proteins are required for Smac mimetic-mediated sensitization of cholangiocarcinoma cells to TNF-α and chemotherapeutic gemcitabine-induced necroptosis.
Akara-Amornthum P; Lomphithak T; Choksi S; Tohtong R; Jitkaew S
PLoS One; 2020; 15(1):e0227454. PubMed ID: 31914150
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
