192 related articles for article (PubMed ID: 37365240)
1. 3D bioengineered neural tissue generated from patient-derived iPSCs mimics time-dependent phenotypes and transcriptional features of Alzheimer's disease.
Lomoio S; Pandey RS; Rouleau N; Menicacci B; Kim W; Cantley WL; Haydon PG; Bennett DA; Young-Pearse TL; Carter GW; Kaplan DL; Tesco G
Mol Psychiatry; 2023 Dec; 28(12):5390-5401. PubMed ID: 37365240
[TBL] [Abstract][Full Text] [Related]
2. Neurons derived from sporadic Alzheimer's disease iPSCs reveal elevated TAU hyperphosphorylation, increased amyloid levels, and GSK3B activation.
Ochalek A; Mihalik B; Avci HX; Chandrasekaran A; Téglási A; Bock I; Giudice ML; Táncos Z; Molnár K; László L; Nielsen JE; Holst B; Freude K; Hyttel P; Kobolák J; Dinnyés A
Alzheimers Res Ther; 2017 Dec; 9(1):90. PubMed ID: 29191219
[TBL] [Abstract][Full Text] [Related]
3. Endoplasmic reticulum stress induces Alzheimer disease-like phenotypes in the neuron derived from the induced pluripotent stem cell with D678H mutation on amyloid precursor protein.
Devina T; Wong YH; Hsiao CW; Li YJ; Lien CC; Cheng IH
J Neurochem; 2022 Oct; 163(1):26-39. PubMed ID: 35943292
[TBL] [Abstract][Full Text] [Related]
4. The familial Alzheimer's disease APPV717I mutation alters APP processing and Tau expression in iPSC-derived neurons.
Muratore CR; Rice HC; Srikanth P; Callahan DG; Shin T; Benjamin LN; Walsh DM; Selkoe DJ; Young-Pearse TL
Hum Mol Genet; 2014 Jul; 23(13):3523-36. PubMed ID: 24524897
[TBL] [Abstract][Full Text] [Related]
5. A Large Panel of Isogenic APP and PSEN1 Mutant Human iPSC Neurons Reveals Shared Endosomal Abnormalities Mediated by APP β-CTFs, Not Aβ.
Kwart D; Gregg A; Scheckel C; Murphy EA; Paquet D; Duffield M; Fak J; Olsen O; Darnell RB; Tessier-Lavigne M
Neuron; 2019 Oct; 104(2):256-270.e5. PubMed ID: 31416668
[TBL] [Abstract][Full Text] [Related]
6. Familial Alzheimer's disease patient-derived neurons reveal distinct mutation-specific effects on amyloid beta.
Arber C; Toombs J; Lovejoy C; Ryan NS; Paterson RW; Willumsen N; Gkanatsiou E; Portelius E; Blennow K; Heslegrave A; Schott JM; Hardy J; Lashley T; Fox NC; Zetterberg H; Wray S
Mol Psychiatry; 2020 Nov; 25(11):2919-2931. PubMed ID: 30980041
[TBL] [Abstract][Full Text] [Related]
7. The Breakthroughs and Caveats of Using Human Pluripotent Stem Cells in Modeling Alzheimer's Disease.
Sahlgren Bendtsen KM; Hall VJ
Cells; 2023 Jan; 12(3):. PubMed ID: 36766763
[TBL] [Abstract][Full Text] [Related]
8. Modeling Alzheimer's Disease by Induced Pluripotent Stem Cells Carrying APP D678H Mutation.
Chang KH; Lee-Chen GJ; Huang CC; Lin JL; Chen YJ; Wei PC; Lo YS; Yao CF; Kuo MW; Chen CM
Mol Neurobiol; 2019 Jun; 56(6):3972-3983. PubMed ID: 30238389
[TBL] [Abstract][Full Text] [Related]
9. APOE4 Causes Widespread Molecular and Cellular Alterations Associated with Alzheimer's Disease Phenotypes in Human iPSC-Derived Brain Cell Types.
Lin YT; Seo J; Gao F; Feldman HM; Wen HL; Penney J; Cam HP; Gjoneska E; Raja WK; Cheng J; Rueda R; Kritskiy O; Abdurrob F; Peng Z; Milo B; Yu CJ; Elmsaouri S; Dey D; Ko T; Yankner BA; Tsai LH
Neuron; 2018 Jun; 98(6):1141-1154.e7. PubMed ID: 29861287
[TBL] [Abstract][Full Text] [Related]
10. The transcriptomic landscape of neurons carrying PSEN1 mutations reveals changes in extracellular matrix components and non-coding gene expression.
Corsi GI; Gadekar VP; Haukedal H; Doncheva NT; Anthon C; Ambardar S; Palakodeti D; Hyttel P; Freude K; Seemann SE; Gorodkin J
Neurobiol Dis; 2023 Mar; 178():105980. PubMed ID: 36572121
[TBL] [Abstract][Full Text] [Related]
11. Alzheimer's disease-related amyloid-β induces synaptotoxicity in human iPS cell-derived neurons.
Nieweg K; Andreyeva A; van Stegen B; Tanriöver G; Gottmann K
Cell Death Dis; 2015 Apr; 6(4):e1709. PubMed ID: 25837485
[TBL] [Abstract][Full Text] [Related]
12. Probing sporadic and familial Alzheimer's disease using induced pluripotent stem cells.
Israel MA; Yuan SH; Bardy C; Reyna SM; Mu Y; Herrera C; Hefferan MP; Van Gorp S; Nazor KL; Boscolo FS; Carson CT; Laurent LC; Marsala M; Gage FH; Remes AM; Koo EH; Goldstein LS
Nature; 2012 Jan; 482(7384):216-20. PubMed ID: 22278060
[TBL] [Abstract][Full Text] [Related]
13. Self-Organizing 3D Human Neural Tissue Derived from Induced Pluripotent Stem Cells Recapitulate Alzheimer's Disease Phenotypes.
Raja WK; Mungenast AE; Lin YT; Ko T; Abdurrob F; Seo J; Tsai LH
PLoS One; 2016; 11(9):e0161969. PubMed ID: 27622770
[TBL] [Abstract][Full Text] [Related]
14. Differential effects of familial Alzheimer's disease-causing mutations on amyloid precursor protein (APP) trafficking, proteolytic conversion, and synaptogenic activity.
Schilling S; Pradhan A; Heesch A; Helbig A; Blennow K; Koch C; Bertgen L; Koo EH; Brinkmalm G; Zetterberg H; Kins S; Eggert S
Acta Neuropathol Commun; 2023 Jun; 11(1):87. PubMed ID: 37259128
[TBL] [Abstract][Full Text] [Related]
15. The Impact of APP on Alzheimer-like Pathogenesis and Gene Expression in Down Syndrome iPSC-Derived Neurons.
Ovchinnikov DA; Korn O; Virshup I; Wells CA; Wolvetang EJ
Stem Cell Reports; 2018 Jul; 11(1):32-42. PubMed ID: 29861166
[TBL] [Abstract][Full Text] [Related]
16. Increased susceptibility to Aβ toxicity in neuronal cultures derived from familial Alzheimer's disease (PSEN1-A246E) induced pluripotent stem cells.
Armijo E; Gonzalez C; Shahnawaz M; Flores A; Davis B; Soto C
Neurosci Lett; 2017 Feb; 639():74-81. PubMed ID: 28034781
[TBL] [Abstract][Full Text] [Related]
17. Amyloid-β precursor protein processing and oxidative stress are altered in human iPSC-derived neuron and astrocyte co-cultures carrying presenillin-1 gene mutations following spontaneous differentiation.
Elsworthy RJ; King MC; Grainger A; Fisher E; Crowe JA; Alqattan S; Ludlam A; Hill DEJ; Aldred S
Mol Cell Neurosci; 2021 Jul; 114():103631. PubMed ID: 34022327
[TBL] [Abstract][Full Text] [Related]
18. RNA-binding protein ELAVL4/HuD ameliorates Alzheimer's disease-related molecular changes in human iPSC-derived neurons.
van der Linden RJ; Gerritsen JS; Liao M; Widomska J; Pearse RV; White FM; Franke B; Young-Pearse TL; Poelmans G
Prog Neurobiol; 2022 Oct; 217():102316. PubMed ID: 35843356
[TBL] [Abstract][Full Text] [Related]
19. Regulation of Alzheimer beta-amyloid precursor trafficking and metabolism.
Gandy S; Petanceska S
Biochim Biophys Acta; 2000 Jul; 1502(1):44-52. PubMed ID: 10899430
[TBL] [Abstract][Full Text] [Related]
20. Behavioral and neural network abnormalities in human APP transgenic mice resemble those of App knock-in mice and are modulated by familial Alzheimer's disease mutations but not by inhibition of BACE1.
Johnson ECB; Ho K; Yu GQ; Das M; Sanchez PE; Djukic B; Lopez I; Yu X; Gill M; Zhang W; Paz JT; Palop JJ; Mucke L
Mol Neurodegener; 2020 Sep; 15(1):53. PubMed ID: 32921309
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
