128 related articles for article (PubMed ID: 37387321)
1. Structure-Activity Relationship and Solubility Studies of N1-Substituted Quinoxaline-2,3-diones as Kainate Receptor Antagonists.
Chałupnik P; Vialko A; Pickering DS; Nielsen B; Bay Y; Skov Kristensen A; Hinkkanen M; Szczepańska K; Karcz T; Latacz G; Johansen TN; Szymańska E
ChemMedChem; 2023 Sep; 18(18):e202300278. PubMed ID: 37387321
[TBL] [Abstract][Full Text] [Related]
2. N1-Substituted Quinoxaline-2,3-diones as Kainate Receptor Antagonists: X-ray Crystallography, Structure-Affinity Relationships, and in Vitro Pharmacology.
Pallesen J; Møllerud S; Frydenvang K; Pickering DS; Bornholdt J; Nielsen B; Pasini D; Han L; Marconi L; Kastrup JS; Johansen TN
ACS Chem Neurosci; 2019 Mar; 10(3):1841-1853. PubMed ID: 30620174
[TBL] [Abstract][Full Text] [Related]
3.
Møllerud S; Hansen RB; Pallesen J; Temperini P; Pasini D; Bornholt J; Nielsen B; Mamedova E; Chalupnik P; Paternain AV; Lerma J; Diaz-delCastillo M; Andreasen JT; Frydenvang K; Kastrup JS; Johansen TN; Pickering DS
ACS Chem Neurosci; 2019 Nov; 10(11):4685-4695. PubMed ID: 31622082
[TBL] [Abstract][Full Text] [Related]
4. Discovery of the First Highly Selective Antagonist of the GluK3 Kainate Receptor Subtype.
Chałupnik P; Vialko A; Pickering DS; Hinkkanen M; Donbosco S; Møller TC; Jensen AA; Nielsen B; Bay Y; Kristensen AS; Johansen TN; Łątka K; Bajda M; Szymańska E
Int J Mol Sci; 2022 Aug; 23(15):. PubMed ID: 35955932
[TBL] [Abstract][Full Text] [Related]
5. Design, synthesis and structure-activity relationships of novel phenylalanine-based amino acids as kainate receptors ligands.
Szymańska E; Chałupnik P; Szczepańska K; Cuñado Moral AM; Pickering DS; Nielsen B; Johansen TN; Kieć-Kononowicz K
Bioorg Med Chem Lett; 2016 Nov; 26(22):5568-5572. PubMed ID: 27765511
[TBL] [Abstract][Full Text] [Related]
6. Structure and Affinity of Two Bicyclic Glutamate Analogues at AMPA and Kainate Receptors.
Møllerud S; Pinto A; Marconi L; Frydenvang K; Thorsen TS; Laulumaa S; Venskutonytė R; Winther S; Moral AMC; Tamborini L; Conti P; Pickering DS; Kastrup JS
ACS Chem Neurosci; 2017 Sep; 8(9):2056-2064. PubMed ID: 28691798
[TBL] [Abstract][Full Text] [Related]
7. In-vitro characterization of YM872, a selective, potent and highly water-soluble alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate receptor antagonist.
Kohara A; Okada M; Tsutsumi R; Ohno K; Takahashi M; Shimizu-Sasamata M; Shishikura J; Inami H; Sakamoto S; Yamaguchi T
J Pharm Pharmacol; 1998 Jul; 50(7):795-801. PubMed ID: 9720630
[TBL] [Abstract][Full Text] [Related]
8. Tritium and deuterium labelling of a kainate receptor antagonist and evaluation as a radioligand.
Chałupnik P; Marek A; Hovah MEL; Pickering DS; Temperini P; Donbosco S; Szymańska E; Johansen TN
J Labelled Comp Radiopharm; 2024 Apr; 67(4):120-130. PubMed ID: 38332677
[TBL] [Abstract][Full Text] [Related]
9. A new pyrrolyl-quinoxalinedione series of non-NMDA glutamate receptor antagonists: pharmacological characterization and comparison with NBQX and valproate in the kindling model of epilepsy.
Löscher W; Lehmann H; Behl B; Seemann D; Teschendorf HJ; Hofmann HP; Lubisch W; Höger T; Lemaire HG; Gross G
Eur J Neurosci; 1999 Jan; 11(1):250-62. PubMed ID: 9987029
[TBL] [Abstract][Full Text] [Related]
10. Quinoxaline derivatives: structure-activity relationships and physiological implications of inhibition of N-methyl-D-aspartate and non-N-methyl-D-aspartate receptor-mediated currents and synaptic potentials.
Randle JC; Guet T; Bobichon C; Moreau C; Curutchet P; Lambolez B; de Carvalho LP; Cordi A; Lepagnol JM
Mol Pharmacol; 1992 Feb; 41(2):337-45. PubMed ID: 1371583
[TBL] [Abstract][Full Text] [Related]
11. Kainate induces various domain closures in AMPA and kainate receptors.
Venskutonytė R; Frydenvang K; Hald H; Rabassa AC; Gajhede M; Ahring PK; Kastrup JS
Neurochem Int; 2012 Sep; 61(4):536-45. PubMed ID: 22425692
[TBL] [Abstract][Full Text] [Related]
12. Pharmacological activity of C10-substituted analogs of the high-affinity kainate receptor agonist dysiherbaine.
Lash-Van Wyhe LL; Postila PA; Tsubone K; Sasaki M; Pentikäinen OT; Sakai R; Swanson GT
Neuropharmacology; 2010 Mar; 58(3):640-9. PubMed ID: 19962997
[TBL] [Abstract][Full Text] [Related]
13. A pharmacological profile of the high-affinity GluK5 kainate receptor.
Møllerud S; Kastrup JS; Pickering DS
Eur J Pharmacol; 2016 Oct; 788():315-320. PubMed ID: 27373850
[TBL] [Abstract][Full Text] [Related]
14. Competitive inhibition by NBQX of kainate/AMPA receptor currents and excitatory synaptic potentials: importance of 6-nitro substitution.
Randle JC; Guet T; Cordi A; Lepagnol JM
Eur J Pharmacol; 1992 May; 215(2-3):237-44. PubMed ID: 1382998
[TBL] [Abstract][Full Text] [Related]
15. YM90K: pharmacological characterization as a selective and potent alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate/kainate receptor antagonist.
Shimizu-Sasamata M; Kawasaki-Yatsugi S; Okada M; Sakamoto S; Yatsugi S; Togami J; Hatanaka K; Ohmori J; Koshiya K; Usuda S; Murase K
J Pharmacol Exp Ther; 1996 Jan; 276(1):84-92. PubMed ID: 8558460
[TBL] [Abstract][Full Text] [Related]
16. Binding site and interlobe interactions of the ionotropic glutamate receptor GluK3 ligand binding domain revealed by high resolution crystal structure in complex with (S)-glutamate.
Venskutonytė R; Frydenvang K; Gajhede M; Bunch L; Pickering DS; Kastrup JS
J Struct Biol; 2011 Dec; 176(3):307-14. PubMed ID: 21907808
[TBL] [Abstract][Full Text] [Related]
17. Structural and pharmacological characterization of phenylalanine-based AMPA receptor antagonists at kainate receptors.
Venskutonytė R; Frydenvang K; Valadés EA; Szymańska E; Johansen TN; Kastrup JS; Pickering DS
ChemMedChem; 2012 Oct; 7(10):1793-8. PubMed ID: 22407805
[TBL] [Abstract][Full Text] [Related]
18. Small-molecule positive allosteric modulation of homomeric kainate receptors GluK1-3: development of screening assays and insight into GluK3 structure.
Bay Y; Venskutonytė R; Frantsen SM; Thorsen TS; Musgaard M; Frydenvang K; Francotte P; Pirotte B; Biggin PC; Kristensen AS; Boesen T; Pickering DS; Gajhede M; Kastrup JS
FEBS J; 2024 Apr; 291(7):1506-1529. PubMed ID: 38145505
[TBL] [Abstract][Full Text] [Related]
19. Antagonism of recombinant and native GluK3-containing kainate receptors.
Perrais D; Pinheiro PS; Jane DE; Mulle C
Neuropharmacology; 2009 Jan; 56(1):131-40. PubMed ID: 18761361
[TBL] [Abstract][Full Text] [Related]
20. 5-(N-oxyaza)-7-substituted-1,4-dihydroquinoxaline-2,3-diones: novel, systemically active and broad spectrum antagonists for NMDA/glycine, AMPA, and kainate receptors.
Cai SX; Huang JC; Espitia SA; Tran M; Ilyin VI; Hawkinson JE; Woodward RM; Weber E; Keana JF
J Med Chem; 1997 Oct; 40(22):3679-86. PubMed ID: 9357535
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
