BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

127 related articles for article (PubMed ID: 37399991)

  • 21. Tau Tubulin Kinase 1 (TTBK1), a new player in the fight against neurodegenerative diseases.
    Nozal V; Martinez A
    Eur J Med Chem; 2019 Jan; 161():39-47. PubMed ID: 30342424
    [TBL] [Abstract][Full Text] [Related]  

  • 22. ARN25068, a versatile starting point towards triple GSK-3β/FYN/DYRK1A inhibitors to tackle tau-related neurological disorders.
    Demuro S; Sauvey C; Tripathi SK; Di Martino RMC; Shi D; Ortega JA; Russo D; Balboni B; Giabbai B; Storici P; Girotto S; Abagyan R; Cavalli A
    Eur J Med Chem; 2022 Feb; 229():114054. PubMed ID: 34959172
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Accelerated neurodegeneration and neuroinflammation in transgenic mice expressing P301L tau mutant and tau-tubulin kinase 1.
    Asai H; Ikezu S; Woodbury ME; Yonemoto GM; Cui L; Ikezu T
    Am J Pathol; 2014 Mar; 184(3):808-18. PubMed ID: 24418258
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Novel screening cascade identifies MKK4 as key kinase regulating Tau phosphorylation at Ser422.
    Grueninger F; Bohrmann B; Christensen K; Graf M; Roth D; Czech C
    Mol Cell Biochem; 2011 Nov; 357(1-2):199-207. PubMed ID: 21638028
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Pathological phosphorylation of tau and TDP-43 by TTBK1 and TTBK2 drives neurodegeneration.
    Taylor LM; McMillan PJ; Liachko NF; Strovas TJ; Ghetti B; Bird TD; Keene CD; Kraemer BC
    Mol Neurodegener; 2018 Feb; 13(1):7. PubMed ID: 29409526
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Ser
    Sandhu P; Naeem MM; Lu C; Kumarathasan P; Gomes J; Basak A
    Bioorg Med Chem Lett; 2017 Feb; 27(3):642-652. PubMed ID: 27989667
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Design, synthesis and biological evaluation of harmine derivatives as potent GSK-3β/DYRK1A dual inhibitors for the treatment of Alzheimer's disease.
    Liu W; Liu X; Tian L; Gao Y; Liu W; Chen H; Jiang X; Xu Z; Ding H; Zhao Q
    Eur J Med Chem; 2021 Oct; 222():113554. PubMed ID: 34098466
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Virtual screening, pharmacokinetics, molecular dynamics and binding free energy analysis for small natural molecules against cyclin-dependent kinase 5 for Alzheimer's disease.
    Shukla R; Singh TR
    J Biomol Struct Dyn; 2020 Jan; 38(1):248-262. PubMed ID: 30688165
    [TBL] [Abstract][Full Text] [Related]  

  • 29. The crystal structure of the catalytic domain of tau tubulin kinase 2 in complex with a small-molecule inhibitor.
    Marcotte DJ; Spilker KA; Wen D; Hesson T; Patterson TA; Kumar PR; Chodaparambil JV
    Acta Crystallogr F Struct Biol Commun; 2020 Mar; 76(Pt 3):103-108. PubMed ID: 32133995
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Structure Based Design and Molecular Docking Studies for Phosphorylated Tau Inhibitors in Alzheimer's Disease.
    Pradeepkiran JA; Reddy PH
    Cells; 2019 Mar; 8(3):. PubMed ID: 30893872
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Genetic variations in tau-tubulin kinase-1 are linked to Alzheimer's disease in a Spanish case-control cohort.
    Vázquez-Higuera JL; Martínez-García A; Sánchez-Juan P; Rodríguez-Rodríguez E; Mateo I; Pozueta A; Frank A; Valdivieso F; Berciano J; Bullido MJ; Combarros O
    Neurobiol Aging; 2011 Mar; 32(3):550.e5-9. PubMed ID: 20096481
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Protective effects of a small molecule inhibitor ligand against hyperphosphorylated tau-induced mitochondrial and synaptic toxicities in Alzheimer disease.
    Pradeepkiran JA; Munikumar M; Reddy AP; Reddy PH
    Hum Mol Genet; 2021 Dec; 31(2):244-261. PubMed ID: 34432046
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Identification of abelson tyrosine kinase inhibitors as potential therapeutics for Alzheimer's disease using multiple e-pharmacophore modeling and molecular dynamics.
    Palakurti R; Vadrevu R
    J Biomol Struct Dyn; 2017 Mar; 35(4):883-896. PubMed ID: 26982633
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Modulation of tau tubulin kinases (TTBK1 and TTBK2) impacts ciliogenesis.
    Bashore FM; Marquez AB; Chaikuad A; Howell S; Dunn AS; Beltran AA; Smith JL; Drewry DH; Beltran AS; Axtman AD
    Sci Rep; 2023 Apr; 13(1):6118. PubMed ID: 37059819
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Tau-tubulin kinase 1 enhances prefibrillar tau aggregation and motor neuron degeneration in P301L FTDP-17 tau-mutant mice.
    Xu J; Sato S; Okuyama S; Swan RJ; Jacobsen MT; Strunk E; Ikezu T
    FASEB J; 2010 Aug; 24(8):2904-15. PubMed ID: 20354135
    [TBL] [Abstract][Full Text] [Related]  

  • 36. An identification of MARK inhibitors using high throughput MALDI-TOF mass spectrometry.
    Hruba L; Polishchuk P; Das V; Hajduch M; Dzubak P
    Biomed Pharmacother; 2022 Feb; 146():112549. PubMed ID: 34923338
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Tau-tubulin kinase 1 phosphorylates TDP-43 at disease-relevant sites and exacerbates TDP-43 pathology.
    Tian Y; Wang Y; Jablonski AM; Hu Y; Sugam JA; Koglin M; Stachel SJ; Zhou H; Uslaner JM; Parmentier-Batteur S
    Neurobiol Dis; 2021 Dec; 161():105548. PubMed ID: 34752923
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Structure-Based Virtual Screening and De Novo Design to Identify Submicromolar Inhibitors of G2019S Mutant of Leucine-Rich Repeat Kinase 2.
    Park H; Kim T; Kim K; Jang A; Hong S
    Int J Mol Sci; 2022 Oct; 23(21):. PubMed ID: 36361616
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Identification of novel scaffold of benzothiazepinones as non-ATP competitive glycogen synthase kinase-3β inhibitors through virtual screening.
    Zhang P; Hu HR; Huang ZH; Lei JY; Chu Y; Ye DY
    Bioorg Med Chem Lett; 2012 Dec; 22(23):7232-6. PubMed ID: 23099099
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Molecular hydrogen attenuates sepsis-induced cognitive dysfunction through regulation of tau phosphorylation.
    Qi B; Song Y; Chen C; Zhao L; Ma W; Meng S; Zhuang X; Lin H; Liang J; Cui Y; Xie K
    Int Immunopharmacol; 2023 Jan; 114():109603. PubMed ID: 36538853
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 7.