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22. Blocking protein farnesylation improves nuclear shape abnormalities in keratinocytes of mice expressing the prelamin A variant in Hutchinson-Gilford progeria syndrome. Wang Y; Ostlund C; Worman HJ Nucleus; 2010; 1(5):432-9. PubMed ID: 21326826 [TBL] [Abstract][Full Text] [Related]
23. Progerin impairs chromosome maintenance by depleting CENP-F from metaphase kinetochores in Hutchinson-Gilford progeria fibroblasts. Eisch V; Lu X; Gabriel D; Djabali K Oncotarget; 2016 Apr; 7(17):24700-18. PubMed ID: 27015553 [TBL] [Abstract][Full Text] [Related]
24. Hutchinson-Gilford progeria mutant lamin A primarily targets human vascular cells as detected by an anti-Lamin A G608G antibody. McClintock D; Gordon LB; Djabali K Proc Natl Acad Sci U S A; 2006 Feb; 103(7):2154-9. PubMed ID: 16461887 [TBL] [Abstract][Full Text] [Related]
25. Hutchinson-Gilford Progeria Syndrome: A premature aging disease caused by LMNA gene mutations. Gonzalo S; Kreienkamp R; Askjaer P Ageing Res Rev; 2017 Jan; 33():18-29. PubMed ID: 27374873 [TBL] [Abstract][Full Text] [Related]
27. Epidermal expression of the truncated prelamin A causing Hutchinson-Gilford progeria syndrome: effects on keratinocytes, hair and skin. Wang Y; Panteleyev AA; Owens DM; Djabali K; Stewart CL; Worman HJ Hum Mol Genet; 2008 Aug; 17(15):2357-69. PubMed ID: 18442998 [TBL] [Abstract][Full Text] [Related]
28. Farnesyltransferase inhibitor and rapamycin correct aberrant genome organisation and decrease DNA damage respectively, in Hutchinson-Gilford progeria syndrome fibroblasts. Bikkul MU; Clements CS; Godwin LS; Goldberg MW; Kill IR; Bridger JM Biogerontology; 2018 Dec; 19(6):579-602. PubMed ID: 29907918 [TBL] [Abstract][Full Text] [Related]
29. Epigenetic involvement in Hutchinson-Gilford progeria syndrome: a mini-review. Arancio W; Pizzolanti G; Genovese SI; Pitrone M; Giordano C Gerontology; 2014; 60(3):197-203. PubMed ID: 24603298 [TBL] [Abstract][Full Text] [Related]
30. Incomplete processing of mutant lamin A in Hutchinson-Gilford progeria leads to nuclear abnormalities, which are reversed by farnesyltransferase inhibition. Glynn MW; Glover TW Hum Mol Genet; 2005 Oct; 14(20):2959-69. PubMed ID: 16126733 [TBL] [Abstract][Full Text] [Related]
31. Hutchinson-Gilford progeria syndrome: clinical findings in three patients carrying the G608G mutation in LMNA and review of the literature. Mazereeuw-Hautier J; Wilson LC; Mohammed S; Smallwood D; Shackleton S; Atherton DJ; Harper JI Br J Dermatol; 2007 Jun; 156(6):1308-14. PubMed ID: 17459035 [TBL] [Abstract][Full Text] [Related]
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40. Inhibiting farnesylation of progerin prevents the characteristic nuclear blebbing of Hutchinson-Gilford progeria syndrome. Capell BC; Erdos MR; Madigan JP; Fiordalisi JJ; Varga R; Conneely KN; Gordon LB; Der CJ; Cox AD; Collins FS Proc Natl Acad Sci U S A; 2005 Sep; 102(36):12879-84. PubMed ID: 16129833 [TBL] [Abstract][Full Text] [Related] [Previous] [Next] [New Search]