348 related articles for article (PubMed ID: 37431963)
1. Loss of TDP-43 oligomerization or RNA binding elicits distinct aggregation patterns.
Pérez-Berlanga M; Wiersma VI; Zbinden A; De Vos L; Wagner U; Foglieni C; Mallona I; Betz KM; Cléry A; Weber J; Guo Z; Rigort R; de Rossi P; Manglunia R; Tantardini E; Sahadevan S; Stach O; Hruska-Plochan M; Allain FH; Paganetti P; Polymenidou M
EMBO J; 2023 Sep; 42(17):e111719. PubMed ID: 37431963
[TBL] [Abstract][Full Text] [Related]
2. Aggresome formation and liquid-liquid phase separation independently induce cytoplasmic aggregation of TAR DNA-binding protein 43.
Watanabe S; Inami H; Oiwa K; Murata Y; Sakai S; Komine O; Sobue A; Iguchi Y; Katsuno M; Yamanaka K
Cell Death Dis; 2020 Oct; 11(10):909. PubMed ID: 33097688
[TBL] [Abstract][Full Text] [Related]
3. Developmentally Regulated RNA-binding Protein 1 (Drb1)/RNA-binding Motif Protein 45 (RBM45), a Nuclear-Cytoplasmic Trafficking Protein, Forms TAR DNA-binding Protein 43 (TDP-43)-mediated Cytoplasmic Aggregates.
Mashiko T; Sakashita E; Kasashima K; Tominaga K; Kuroiwa K; Nozaki Y; Matsuura T; Hamamoto T; Endo H
J Biol Chem; 2016 Jul; 291(29):14996-5007. PubMed ID: 27226551
[TBL] [Abstract][Full Text] [Related]
4. The RNA-binding motif 45 (RBM45) protein accumulates in inclusion bodies in amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration with TDP-43 inclusions (FTLD-TDP) patients.
Collins M; Riascos D; Kovalik T; An J; Krupa K; Krupa K; Hood BL; Conrads TP; Renton AE; Traynor BJ; Bowser R
Acta Neuropathol; 2012 Nov; 124(5):717-32. PubMed ID: 22993125
[TBL] [Abstract][Full Text] [Related]
5. Molecular Dissection of TDP-43 as a Leading Cause of ALS/FTLD.
Tamaki Y; Urushitani M
Int J Mol Sci; 2022 Oct; 23(20):. PubMed ID: 36293362
[TBL] [Abstract][Full Text] [Related]
6. Reappraisal of the anatomical spreading and propagation hypothesis about TDP-43 aggregation in amyotrophic lateral sclerosis and frontotemporal lobar degeneration.
Riku Y
Neuropathology; 2020 Oct; 40(5):426-435. PubMed ID: 32157757
[TBL] [Abstract][Full Text] [Related]
7. Low molecular weight species of TDP-43 generated by abnormal splicing form inclusions in amyotrophic lateral sclerosis and result in motor neuron death.
Xiao S; Sanelli T; Chiang H; Sun Y; Chakrabartty A; Keith J; Rogaeva E; Zinman L; Robertson J
Acta Neuropathol; 2015 Jul; 130(1):49-61. PubMed ID: 25788357
[TBL] [Abstract][Full Text] [Related]
8. Pathway from TDP-43-Related Pathology to Neuronal Dysfunction in Amyotrophic Lateral Sclerosis and Frontotemporal Lobar Degeneration.
Riku Y; Seilhean D; Duyckaerts C; Boluda S; Iguchi Y; Ishigaki S; Iwasaki Y; Yoshida M; Sobue G; Katsuno M
Int J Mol Sci; 2021 Apr; 22(8):. PubMed ID: 33917673
[TBL] [Abstract][Full Text] [Related]
9. TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration.
Wils H; Kleinberger G; Janssens J; Pereson S; Joris G; Cuijt I; Smits V; Ceuterick-de Groote C; Van Broeckhoven C; Kumar-Singh S
Proc Natl Acad Sci U S A; 2010 Feb; 107(8):3858-63. PubMed ID: 20133711
[TBL] [Abstract][Full Text] [Related]
10. Distinct TDP-43 inclusion morphologies in frontotemporal lobar degeneration with and without amyotrophic lateral sclerosis.
Tan RH; Yang Y; Kim WS; Dobson-Stone C; Kwok JB; Kiernan MC; Halliday GM
Acta Neuropathol Commun; 2017 Oct; 5(1):76. PubMed ID: 29078806
[TBL] [Abstract][Full Text] [Related]
11. How do the RNA-binding proteins TDP-43 and FUS relate to amyotrophic lateral sclerosis and frontotemporal degeneration, and to each other?
Baloh RH
Curr Opin Neurol; 2012 Dec; 25(6):701-7. PubMed ID: 23041957
[TBL] [Abstract][Full Text] [Related]
12. Detection of TAR DNA-binding protein 43 (TDP-43) oligomers as initial intermediate species during aggregate formation.
French RL; Grese ZR; Aligireddy H; Dhavale DD; Reeb AN; Kedia N; Kotzbauer PT; Bieschke J; Ayala YM
J Biol Chem; 2019 Apr; 294(17):6696-6709. PubMed ID: 30824544
[TBL] [Abstract][Full Text] [Related]
13. [The molecular mechanisms of intracellular TDP-43 aggregates].
Nonaka T; Arai T; Hasegawa M
Brain Nerve; 2009 Nov; 61(11):1292-300. PubMed ID: 19938686
[TBL] [Abstract][Full Text] [Related]
14. Nuclear import impairment causes cytoplasmic trans-activation response DNA-binding protein accumulation and is associated with frontotemporal lobar degeneration.
Nishimura AL; Zupunski V; Troakes C; Kathe C; Fratta P; Howell M; Gallo JM; Hortobágyi T; Shaw CE; Rogelj B
Brain; 2010 Jun; 133(Pt 6):1763-71. PubMed ID: 20472655
[TBL] [Abstract][Full Text] [Related]
15. The role of TDP-43 in the pathogenesis of ALS and FTLD.
Baralle M; Buratti E; Baralle FE
Biochem Soc Trans; 2013 Dec; 41(6):1536-40. PubMed ID: 24256250
[TBL] [Abstract][Full Text] [Related]
16. Molecular Mechanisms Underlying TDP-43 Pathology in Cellular and Animal Models of ALS and FTLD.
Wood A; Gurfinkel Y; Polain N; Lamont W; Lyn Rea S
Int J Mol Sci; 2021 Apr; 22(9):. PubMed ID: 33946763
[TBL] [Abstract][Full Text] [Related]
17. Lower motor neuron involvement in TAR DNA-binding protein of 43 kDa-related frontotemporal lobar degeneration and amyotrophic lateral sclerosis.
Riku Y; Watanabe H; Yoshida M; Tatsumi S; Mimuro M; Iwasaki Y; Katsuno M; Iguchi Y; Masuda M; Senda J; Ishigaki S; Udagawa T; Sobue G
JAMA Neurol; 2014 Feb; 71(2):172-9. PubMed ID: 24378564
[TBL] [Abstract][Full Text] [Related]
18. Amyotrophic lateral sclerosis and frontotemporal lobar degeneration: a spectrum of TDP-43 proteinopathies.
Geser F; Lee VM; Trojanowski JQ
Neuropathology; 2010 Apr; 30(2):103-12. PubMed ID: 20102519
[TBL] [Abstract][Full Text] [Related]
19. Cytoplasmic poly-GA aggregates impair nuclear import of TDP-43 in C9orf72 ALS/FTLD.
Khosravi B; Hartmann H; May S; Möhl C; Ederle H; Michaelsen M; Schludi MH; Dormann D; Edbauer D
Hum Mol Genet; 2017 Feb; 26(4):790-800. PubMed ID: 28040728
[TBL] [Abstract][Full Text] [Related]
20. Quantification of the Relative Contributions of Loss-of-function and Gain-of-function Mechanisms in TAR DNA-binding Protein 43 (TDP-43) Proteinopathies.
Cascella R; Capitini C; Fani G; Dobson CM; Cecchi C; Chiti F
J Biol Chem; 2016 Sep; 291(37):19437-48. PubMed ID: 27445339
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
