241 related articles for article (PubMed ID: 37442129)
1. Distinct layers of BRD4-PTEFb reveal bromodomain-independent function in transcriptional regulation.
Zheng B; Gold S; Iwanaszko M; Howard BC; Wang L; Shilatifard A
Mol Cell; 2023 Aug; 83(16):2896-2910.e4. PubMed ID: 37442129
[TBL] [Abstract][Full Text] [Related]
2. Affinity map of bromodomain protein 4 (BRD4) interactions with the histone H4 tail and the small molecule inhibitor JQ1.
Jung M; Philpott M; Müller S; Schulze J; Badock V; Eberspächer U; Moosmayer D; Bader B; Schmees N; Fernández-Montalván A; Haendler B
J Biol Chem; 2014 Mar; 289(13):9304-19. PubMed ID: 24497639
[TBL] [Abstract][Full Text] [Related]
3. BRD4 assists elongation of both coding and enhancer RNAs by interacting with acetylated histones.
Kanno T; Kanno Y; LeRoy G; Campos E; Sun HW; Brooks SR; Vahedi G; Heightman TD; Garcia BA; Reinberg D; Siebenlist U; O'Shea JJ; Ozato K
Nat Struct Mol Biol; 2014 Dec; 21(12):1047-57. PubMed ID: 25383670
[TBL] [Abstract][Full Text] [Related]
4. BRD4 bimodal binding at promoters and drug-induced displacement at Pol II pause sites associates with I-BET sensitivity.
Khoueiry P; Ward Gahlawat A; Petretich M; Michon AM; Simola D; Lam E; Furlong EE; Benes V; Dawson MA; Prinjha RK; Drewes G; Grandi P
Epigenetics Chromatin; 2019 Jul; 12(1):39. PubMed ID: 31266503
[TBL] [Abstract][Full Text] [Related]
5. The Brd4 extraterminal domain confers transcription activation independent of pTEFb by recruiting multiple proteins, including NSD3.
Rahman S; Sowa ME; Ottinger M; Smith JA; Shi Y; Harper JW; Howley PM
Mol Cell Biol; 2011 Jul; 31(13):2641-52. PubMed ID: 21555454
[TBL] [Abstract][Full Text] [Related]
6. RNA polymerase II stalling promotes nucleosome occlusion and pTEFb recruitment to drive immortalization by Epstein-Barr virus.
Palermo RD; Webb HM; West MJ
PLoS Pathog; 2011 Oct; 7(10):e1002334. PubMed ID: 22046134
[TBL] [Abstract][Full Text] [Related]
7. Bromodomain-containing protein 4 (BRD4) regulates RNA polymerase II serine 2 phosphorylation in human CD4+ T cells.
Zhang W; Prakash C; Sum C; Gong Y; Li Y; Kwok JJ; Thiessen N; Pettersson S; Jones SJ; Knapp S; Yang H; Chin KC
J Biol Chem; 2012 Dec; 287(51):43137-55. PubMed ID: 23086925
[TBL] [Abstract][Full Text] [Related]
8. Comparative structure-function analysis of bromodomain and extraterminal motif (BET) proteins in a gene-complementation system.
Werner MT; Wang H; Hamagami N; Hsu SC; Yano JA; Stonestrom AJ; Behera V; Zong Y; Mackay JP; Blobel GA
J Biol Chem; 2020 Feb; 295(7):1898-1914. PubMed ID: 31792058
[TBL] [Abstract][Full Text] [Related]
9. Bromodomain protein Brd4 associated with acetylated chromatin is important for maintenance of higher-order chromatin structure.
Wang R; Li Q; Helfer CM; Jiao J; You J
J Biol Chem; 2012 Mar; 287(14):10738-52. PubMed ID: 22334664
[TBL] [Abstract][Full Text] [Related]
10. Metabolically Derived Lysine Acylations and Neighboring Modifications Tune the Binding of the BET Bromodomains to Histone H4.
Olp MD; Zhu N; Smith BC
Biochemistry; 2017 Oct; 56(41):5485-5495. PubMed ID: 28945351
[TBL] [Abstract][Full Text] [Related]
11. Covalent-Fragment Screening of BRD4 Identifies a Ligandable Site Orthogonal to the Acetyl-Lysine Binding Sites.
Olp MD; Sprague DJ; Goetz CJ; Kathman SG; Wynia-Smith SL; Shishodia S; Summers SB; Xu Z; Statsyuk AV; Smith BC
ACS Chem Biol; 2020 Apr; 15(4):1036-1049. PubMed ID: 32149490
[TBL] [Abstract][Full Text] [Related]
12. Transcriptional elongation control of hypoxic response.
Soliman SHA; Iwanaszko M; Zheng B; Gold S; Howard BC; Das M; Chakrabarty RP; Chandel NS; Shilatifard A
Proc Natl Acad Sci U S A; 2024 Apr; 121(15):e2321502121. PubMed ID: 38564636
[TBL] [Abstract][Full Text] [Related]
13. Structures of the dual bromodomains of the P-TEFb-activating protein Brd4 at atomic resolution.
Vollmuth F; Blankenfeldt W; Geyer M
J Biol Chem; 2009 Dec; 284(52):36547-36556. PubMed ID: 19828451
[TBL] [Abstract][Full Text] [Related]
14. RNAs interact with BRD4 to promote enhanced chromatin engagement and transcription activation.
Rahnamoun H; Lee J; Sun Z; Lu H; Ramsey KM; Komives EA; Lauberth SM
Nat Struct Mol Biol; 2018 Aug; 25(8):687-697. PubMed ID: 30076409
[TBL] [Abstract][Full Text] [Related]
15. Signal-induced Brd4 release from chromatin is essential for its role transition from chromatin targeting to transcriptional regulation.
Ai N; Hu X; Ding F; Yu B; Wang H; Lu X; Zhang K; Li Y; Han A; Lin W; Liu R; Chen R
Nucleic Acids Res; 2011 Dec; 39(22):9592-604. PubMed ID: 21890894
[TBL] [Abstract][Full Text] [Related]
16. Histone cross-talk connects protein phosphatase 1α (PP1α) and histone deacetylase (HDAC) pathways to regulate the functional transition of bromodomain-containing 4 (BRD4) for inducible gene expression.
Hu X; Lu X; Liu R; Ai N; Cao Z; Li Y; Liu J; Yu B; Liu K; Wang H; Zhou C; Wang Y; Han A; Ding F; Chen R
J Biol Chem; 2014 Aug; 289(33):23154-23167. PubMed ID: 24939842
[TBL] [Abstract][Full Text] [Related]
17. A BRD4-mediated elongation control point primes transcribing RNA polymerase II for 3'-processing and termination.
Arnold M; Bressin A; Jasnovidova O; Meierhofer D; Mayer A
Mol Cell; 2021 Sep; 81(17):3589-3603.e13. PubMed ID: 34324863
[TBL] [Abstract][Full Text] [Related]
18. Phospho switch triggers Brd4 chromatin binding and activator recruitment for gene-specific targeting.
Wu SY; Lee AY; Lai HT; Zhang H; Chiang CM
Mol Cell; 2013 Mar; 49(5):843-57. PubMed ID: 23317504
[TBL] [Abstract][Full Text] [Related]
19. Distinct Roles of Brd2 and Brd4 in Potentiating the Transcriptional Program for Th17 Cell Differentiation.
Cheung KL; Zhang F; Jaganathan A; Sharma R; Zhang Q; Konuma T; Shen T; Lee JY; Ren C; Chen CH; Lu G; Olson MR; Zhang W; Kaplan MH; Littman DR; Walsh MJ; Xiong H; Zeng L; Zhou MM
Mol Cell; 2017 Mar; 65(6):1068-1080.e5. PubMed ID: 28262505
[TBL] [Abstract][Full Text] [Related]
20. The double bromodomain-containing chromatin adaptor Brd4 and transcriptional regulation.
Wu SY; Chiang CM
J Biol Chem; 2007 May; 282(18):13141-5. PubMed ID: 17329240
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
