BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

138 related articles for article (PubMed ID: 37458164)

  • 1. Physiologically relevant fluorescent assay for identification of 17β-hydroxysteroid dehydrogenase type 10 inhibitors.
    Schmidt M; Vaskova M; Rotterova A; Fiandova P; Miskerikova M; Zemanova L; Benek O; Musilek K
    J Neurochem; 2023 Oct; 167(2):154-167. PubMed ID: 37458164
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Nanomolar Benzothiazole-Based Inhibitors of 17β-HSD10 with Cellular Bioactivity.
    Hanzlova M; Miskerikova MS; Rotterova A; Chalupova K; Jurkova K; Hamsikova M; Andrys R; Haleckova A; Svobodova J; Schmidt M; Benek O; Musilek K
    ACS Med Chem Lett; 2023 Dec; 14(12):1724-1732. PubMed ID: 38116418
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Identification of steroidal derivatives inhibiting the transformations of allopregnanolone and estradiol by 17β-hydroxysteroid dehydrogenase type 10.
    Boutin S; Roy J; Maltais R; Alata W; Calon F; Poirier D
    Bioorg Med Chem Lett; 2018 Dec; 28(22):3554-3559. PubMed ID: 30297283
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Novel Benzothiazole-based Ureas as 17β-HSD10 Inhibitors, A Potential Alzheimer's Disease Treatment.
    Aitken L; Benek O; McKelvie BE; Hughes RE; Hroch L; Schmidt M; Major LL; Vinklarova L; Kuca K; Smith TK; Musilek K; Gunn-Moore FJ
    Molecules; 2019 Jul; 24(15):. PubMed ID: 31362457
    [No Abstract]   [Full Text] [Related]  

  • 5. Roles of 17β-hydroxysteroid dehydrogenase type 10 in neurodegenerative disorders.
    Yang SY; He XY; Isaacs C; Dobkin C; Miller D; Philipp M
    J Steroid Biochem Mol Biol; 2014 Sep; 143():460-72. PubMed ID: 25007702
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Involvement of Type 10 17β-Hydroxysteroid Dehydrogenase in the Pathogenesis of Infantile Neurodegeneration and Alzheimer's Disease.
    He XY; Frackowiak J; Dobkin C; Brown WT; Yang SY
    Int J Mol Sci; 2023 Dec; 24(24):. PubMed ID: 38139430
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Benzothiazolyl Ureas are Low Micromolar and Uncompetitive Inhibitors of 17β-HSD10 with Implications to Alzheimer's Disease Treatment.
    Schmidt M; Benek O; Vinklarova L; Hrabinova M; Zemanova L; Chribek M; Kralova V; Hroch L; Dolezal R; Lycka A; Prchal L; Jun D; Aitken L; Gunn-Moore F; Kuca K; Musilek K
    Int J Mol Sci; 2020 Mar; 21(6):. PubMed ID: 32192199
    [TBL] [Abstract][Full Text] [Related]  

  • 8. 6-benzothiazolyl ureas, thioureas and guanidines are potent inhibitors of ABAD/17β-HSD10 and potential drugs for Alzheimer's disease treatment: Design, synthesis and in vitro evaluation.
    Benek O; Hroch L; Aitken L; Dolezal R; Guest P; Benkova M; Soukup O; Musil K; Kuca K; Smith TK; Gunn-Moore F; Musilek K
    Med Chem; 2017 Jan; ():. PubMed ID: 28067167
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design, synthesis and in vitro evaluation of benzothiazole-based ureas as potential ABAD/17β-HSD10 modulators for Alzheimer's disease treatment.
    Hroch L; Benek O; Guest P; Aitken L; Soukup O; Janockova J; Musil K; Dohnal V; Dolezal R; Kuca K; Smith TK; Gunn-Moore F; Musilek K
    Bioorg Med Chem Lett; 2016 Aug; 26(15):3675-8. PubMed ID: 27287370
    [TBL] [Abstract][Full Text] [Related]  

  • 10. C-3 Steroidal Hemiesters as Inhibitors of 17β-Hydroxysteroid Dehydrogenase Type 10.
    Hanzlova M; Slavikova B; Morozovova M; Musilek K; Rotterova A; Zemanová L; Kudova E
    ACS Omega; 2024 Mar; 9(10):12116-12124. PubMed ID: 38496976
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Development of submicromolar 17β-HSD10 inhibitors and their in vitro and in vivo evaluation.
    Benek O; Vaskova M; Miskerikova M; Schmidt M; Andrys R; Rotterova A; Skarka A; Hatlapatkova J; Karasova JZ; Medvecky M; Hroch L; Vinklarova L; Fisar Z; Hroudova J; Handl J; Capek J; Rousar T; Kobrlova T; Dolezal R; Soukup O; Aitken L; Gunn-Moore F; Musilek K
    Eur J Med Chem; 2023 Oct; 258():115593. PubMed ID: 37390508
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Intracellular oxidation of allopregnanolone by human brain type 10 17beta-hydroxysteroid dehydrogenase.
    He XY; Wegiel J; Yang SY
    Brain Res; 2005 Apr; 1040(1-2):29-35. PubMed ID: 15804423
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Levels of 17β-Hydroxysteroid Dehydrogenase Type 10 in Cerebrospinal Fluid of People with Mild Cognitive Impairment and Various Types of Dementias.
    Kristofikova Z; Ricny J; Vyhnalek M; Hort J; Laczo J; Sirova J; Klaschka J; Ripova D
    J Alzheimers Dis; 2015; 48(1):105-14. PubMed ID: 26401932
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Infantile Neurodegeneration Results from Mutants of 17β-Hydroxysteroid Dehydrogenase Type 10 Rather Than Aβ-Binding Alcohol Dehydrogenase.
    He XY; Dobkin C; Brown WT; Yang SY
    Int J Mol Sci; 2023 May; 24(10):. PubMed ID: 37239833
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Interactions of 17β-Hydroxysteroid Dehydrogenase Type 10 and Cyclophilin D in Alzheimer's Disease.
    Kristofikova Z; Springer T; Gedeonova E; Hofmannova A; Ricny J; Hromadkova L; Vyhnalek M; Laczo J; Nikolai T; Hort J; Petrasek T; Stuchlik A; Vales K; Klaschka J; Homola J
    Neurochem Res; 2020 Apr; 45(4):915-927. PubMed ID: 31997103
    [TBL] [Abstract][Full Text] [Related]  

  • 16. (-)-CHANA, a fluorogenic probe for detecting amyloid binding alcohol dehydrogenase HSD10 activity in living cells.
    Muirhead KE; Froemming M; Li X; Musilek K; Conway SJ; Sames D; Gunn-Moore FJ
    ACS Chem Biol; 2010 Dec; 5(12):1105-14. PubMed ID: 20836522
    [TBL] [Abstract][Full Text] [Related]  

  • 17. In vitro study of interaction of 17β-hydroxysteroid dehydrogenase type 10 and cyclophilin D and its potential implications for Alzheimer's disease.
    Hemmerová E; Špringer T; Krištofiková Z; Homola J
    Sci Rep; 2019 Nov; 9(1):16700. PubMed ID: 31723183
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Roles of Mitochondrial 17β-Hydroxysteroid Dehydrogenase Type 10 in Alzheimer's Disease.
    He XY; Isaacs C; Yang SY
    J Alzheimers Dis; 2018; 62(2):665-673. PubMed ID: 29480196
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Morphology-Specific Inhibition of β-Amyloid Aggregates by 17β-Hydroxysteroid Dehydrogenase Type 10.
    Aitken L; Quinn SD; Perez-Gonzalez C; Samuel ID; Penedo JC; Gunn-Moore FJ
    Chembiochem; 2016 Jun; 17(11):1029-37. PubMed ID: 26991863
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis of 17β-hydroxysteroid dehydrogenase type 10 steroidal inhibitors: Selectivity, metabolic stability and enhanced potency.
    Boutin S; Maltais R; Roy J; Poirier D
    Eur J Med Chem; 2021 Jan; 209():112909. PubMed ID: 33081987
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.