155 related articles for article (PubMed ID: 37463544)
1. An orally administered enzyme therapeutic for homocystinuria that suppresses homocysteine by metabolizing methionine in the gastrointestinal tract.
Skvorak K; Mitchell V; Teadt L; Franklin KA; Lee HO; Kruse N; Huitt-Roehl C; Hang J; Du F; Galanie S; Guan S; Aijaz H; Zhang N; Rajkovic G; Kruger WD; Ismaili MHA; Huisman G; McCluskie K; Silverman AP
Mol Genet Metab; 2023 Aug; 139(4):107653. PubMed ID: 37463544
[TBL] [Abstract][Full Text] [Related]
2. Behavior, body composition, and vascular phenotype of homocystinuric mice on methionine-restricted diet or enzyme replacement therapy.
Majtan T; Park I; Cox A; Branchford BR; di Paola J; Bublil EM; Kraus JP
FASEB J; 2019 Nov; 33(11):12477-12486. PubMed ID: 31450979
[TBL] [Abstract][Full Text] [Related]
3. Derangement of hepatic polyamine, folate, and methionine cycle metabolism in cystathionine beta-synthase-deficient homocystinuria in the presence and absence of treatment: Possible implications for pathogenesis.
Maclean KN; Jiang H; Phinney WN; Mclagan BM; Roede JR; Stabler SP
Mol Genet Metab; 2021 Feb; 132(2):128-138. PubMed ID: 33483253
[TBL] [Abstract][Full Text] [Related]
4. Classical homocystinuria: From cystathionine beta-synthase deficiency to novel enzyme therapies.
Bublil EM; Majtan T
Biochimie; 2020 Jun; 173():48-56. PubMed ID: 31857119
[TBL] [Abstract][Full Text] [Related]
5. Long-term betaine therapy in a murine model of cystathionine beta-synthase deficient homocystinuria: decreased efficacy over time reveals a significant threshold effect between elevated homocysteine and thrombotic risk.
Maclean KN; Jiang H; Greiner LS; Allen RH; Stabler SP
Mol Genet Metab; 2012 Mar; 105(3):395-403. PubMed ID: 22192524
[TBL] [Abstract][Full Text] [Related]
6. Betaine supplementation is less effective than methionine restriction in correcting phenotypes of CBS deficient mice.
Gupta S; Wang L; Kruger WD
J Inherit Metab Dis; 2016 Jan; 39(1):39-46. PubMed ID: 26231230
[TBL] [Abstract][Full Text] [Related]
7. Expression of mutant human cystathionine beta-synthase rescues neonatal lethality but not homocystinuria in a mouse model.
Wang L; Chen X; Tang B; Hua X; Klein-Szanto A; Kruger WD
Hum Mol Genet; 2005 Aug; 14(15):2201-8. PubMed ID: 15972722
[TBL] [Abstract][Full Text] [Related]
8. The live biotherapeutic SYNB1353 decreases plasma methionine via directed degradation in animal models and healthy volunteers.
Perreault M; Means J; Gerson E; James M; Cotton S; Bergeron CG; Simon M; Carlin DA; Schmidt N; Moore TC; Blasbalg J; Sondheimer N; Ndugga-Kabuye K; Denney WS; Isabella VM; Lubkowicz D; Brennan A; Hava DL
Cell Host Microbe; 2024 Mar; 32(3):382-395.e10. PubMed ID: 38309259
[TBL] [Abstract][Full Text] [Related]
9. Interplay of Enzyme Therapy and Dietary Management of Murine Homocystinuria.
Park I; Bublil EM; Glavin F; Majtan T
Nutrients; 2020 Sep; 12(9):. PubMed ID: 32971905
[TBL] [Abstract][Full Text] [Related]
10. The effect of dietary modulation of sulfur amino acids on cystathionine β synthase-deficient mice.
Kruger WD; Gupta S
Ann N Y Acad Sci; 2016 Jan; 1363(1):80-90. PubMed ID: 26599618
[TBL] [Abstract][Full Text] [Related]
11. Recent therapeutic approaches to cystathionine beta-synthase-deficient homocystinuria.
Majtan T; Kožich V; Kruger WD
Br J Pharmacol; 2023 Feb; 180(3):264-278. PubMed ID: 36417581
[TBL] [Abstract][Full Text] [Related]
12. Enzyme Replacement Therapy Ameliorates Multiple Symptoms of Murine Homocystinuria.
Majtan T; Jones W; Krijt J; Park I; Kruger WD; Kožich V; Bassnett S; Bublil EM; Kraus JP
Mol Ther; 2018 Mar; 26(3):834-844. PubMed ID: 29398487
[TBL] [Abstract][Full Text] [Related]
13. Enzyme replacement prevents neonatal death, liver damage, and osteoporosis in murine homocystinuria.
Majtan T; Hůlková H; Park I; Krijt J; Kožich V; Bublil EM; Kraus JP
FASEB J; 2017 Dec; 31(12):5495-5506. PubMed ID: 28821635
[TBL] [Abstract][Full Text] [Related]
14. Taurine alleviates repression of betaine-homocysteine
Maclean KN; Jiang H; Phinney WN; Keating AK; Hurt KJ; Stabler SP
FASEB J; 2019 May; 33(5):6339-6353. PubMed ID: 30768359
[TBL] [Abstract][Full Text] [Related]
15. Enzyme replacement with PEGylated cystathionine β-synthase ameliorates homocystinuria in murine model.
Bublil EM; Majtan T; Park I; Carrillo RS; Hůlková H; Krijt J; Kožich V; Kraus JP
J Clin Invest; 2016 Jun; 126(6):2372-84. PubMed ID: 27183385
[TBL] [Abstract][Full Text] [Related]
16. Targeting Cystathionine Beta-Synthase Misfolding in Homocystinuria by Small Ligands: State of the Art and Future Directions.
Majtan T; Pey AL; Ereño-Orbea J; Martínez-Cruz LA; Kraus JP
Curr Drug Targets; 2016; 17(13):1455-70. PubMed ID: 26931358
[TBL] [Abstract][Full Text] [Related]
17. Long-term functional correction of cystathionine β-synthase deficiency in mice by adeno-associated viral gene therapy.
Lee HO; Salami CO; Sondhi D; Kaminsky SM; Crystal RG; Kruger WD
J Inherit Metab Dis; 2021 Nov; 44(6):1382-1392. PubMed ID: 34528713
[TBL] [Abstract][Full Text] [Related]
18. Potential Pharmacological Chaperones for Cystathionine Beta-Synthase-Deficient Homocystinuria.
Majtan T; Pey AL; Gimenez-Mascarell P; Martínez-Cruz LA; Szabo C; Kožich V; Kraus JP
Handb Exp Pharmacol; 2018; 245():345-383. PubMed ID: 29119254
[TBL] [Abstract][Full Text] [Related]
19. Cystathionine β-synthase deficiency: Of mice and men.
Kruger WD
Mol Genet Metab; 2017 Jul; 121(3):199-205. PubMed ID: 28583326
[TBL] [Abstract][Full Text] [Related]
20. Treatment of Cystathionine β-Synthase Deficiency in Mice Using a Minicircle-Based Naked DNA Vector.
Lee HO; Gallego-Villar L; Grisch-Chan HM; Häberle J; Thöny B; Kruger WD
Hum Gene Ther; 2019 Sep; 30(9):1093-1100. PubMed ID: 31084364
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
