These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

108 related articles for article (PubMed ID: 3746818)

  • 1. Thiol addition to quinones: model reactions for the inactivation of thymidylate synthase by 5-p-benzoquinonyl-2'-deoxyuridine 5'-phosphate.
    Vadnere MK; Maggiora L; Mertes MP
    J Med Chem; 1986 Sep; 29(9):1714-20. PubMed ID: 3746818
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 5-p-benzoquinonyl-2'-deoxyuridine 5'-phosphate: a possible mechanism-based inhibitor of thymidylate synthetase.
    Maggiora L; Chang CT; Hasson ME; Bigge CF; Mertes MP
    J Med Chem; 1983 Jul; 26(7):1028-36. PubMed ID: 6408258
    [TBL] [Abstract][Full Text] [Related]  

  • 3. 5-Quinone derivatives of 2'-deoxyuridine 5'-phosphate: inhibition and inactivation of thymidylate synthase, antitumor cell, and antiviral studies.
    Al-Razzak LA; Schwepler D; Decedue CJ; Balzarini J; De Clercq E; Mertes MP
    J Med Chem; 1987 Feb; 30(2):409-19. PubMed ID: 3027341
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 5 (alpha-bromoacetyl)-2'=deoxyuridine 5'-phosphate: a mechanism based affinity label for thymidylate synthetase.
    Brouillette CB; Chang CT; Mertes MP
    Biochem Biophys Res Commun; 1979 Mar; 87(2):613-8. PubMed ID: 109088
    [No Abstract]   [Full Text] [Related]  

  • 5. 5-(alpha-Bromoacetyl)-2'-deoxyuridine 5'-phosphate: an affinity label for thymidylate synthetase.
    Brouillette CB; Chang CT; Mertes MP
    J Med Chem; 1979 Dec; 22(12):1541-4. PubMed ID: 119854
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Polycyclic aromatic hydrocarbon (PAH) ortho-quinone conjugate chemistry: kinetics of thiol addition to PAH ortho-quinones and structures of thioether adducts of naphthalene-1,2-dione.
    Murty VS; Penning TM
    Chem Biol Interact; 1992 Sep; 84(2):169-88. PubMed ID: 1394622
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mechanism-based inactivation of thymidylate synthase by 5-(3-fluoropropyn-1-yl)-2'-deoxyuridine 5'-phosphate.
    Kalman TI; Nie Z; Kamat A
    Bioorg Med Chem Lett; 2000 Feb; 10(4):391-4. PubMed ID: 10714507
    [TBL] [Abstract][Full Text] [Related]  

  • 8. 5-propynylpyrimidine nucleoside derivatives: rationally designed mechanism-based inactivators of thymidylate synthase.
    Kalman TI; Nie Z; Kamat A
    Nucleosides Nucleotides Nucleic Acids; 2001; 20(4-7):869-71. PubMed ID: 11563134
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Linear free energy relationship studies of enzyme active site binding: thymidylate synthase.
    Chang G; Schwepler D; Decedue CJ; Balzarini J; De Clercq E; Mertes MP
    J Med Chem; 1988 Jun; 31(6):1141-7. PubMed ID: 3373483
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The inactivation of thymidylate synthase by periodate.
    Ivery TC; Daron HH; Aull JL
    J Inorg Biochem; 1984 Dec; 22(4):259-70. PubMed ID: 6097648
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Reductive addition of glutathione to p-benzoquinone, 2-hydroxy-p-benzoquinone, and p-benzoquinone epoxides. Effect of the hydroxy- and glutathionyl substituents on p-benzohydroquinone autoxidation.
    Brunmark A; Cadenas E
    Chem Biol Interact; 1988; 68(3-4):273-98. PubMed ID: 3214888
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Fluorinated pyrimidines as tight-binding inhibitors of thymidylate synthetase.
    Danenberg PV; Lockshin A
    Pharmacol Ther; 1981; 13(1):69-90. PubMed ID: 6455671
    [No Abstract]   [Full Text] [Related]  

  • 13. Thymidylate synthetase. Catalysis of dehalogenation of 5-bromo- and 5-iodo-2'-deoxyuridylate.
    Garrett C; Wataya Y; Santi DV
    Biochemistry; 1979 Jun; 18(13):2798-804. PubMed ID: 476052
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Studies on the interaction with thymidylate synthase of analogues of 2'-deoxyuridine-5'-phosphate and 5-fluoro-2'-deoxyuridine-5'-phosphate with modified phosphate groups.
    Rode W; Kulikowski T; Kedzierska B; Shugar D
    Biochem Pharmacol; 1987 Jan; 36(2):203-10. PubMed ID: 3814166
    [TBL] [Abstract][Full Text] [Related]  

  • 15. 5-Nitro-2'-deoxyuridine and 5-nitro-2'-deoxyuridine 5'-monophosphate: antiviral activity and inhibition of thymidylate synthetase in vivo.
    De Clercq E; Descamps J; Huang GF; Torrence PF
    Mol Pharmacol; 1978 May; 14(3):422-30. PubMed ID: 661811
    [No Abstract]   [Full Text] [Related]  

  • 16. Inhibition of mammalian tumour thymidylate synthetase by 2'-deoxyuridine 5'-phosphate analogues.
    Rode W; Kulikowski T; Kedzierska B; Shugar D
    Drugs Exp Clin Res; 1986; 12(6-7):545-9. PubMed ID: 3743372
    [TBL] [Abstract][Full Text] [Related]  

  • 17. 5(E)-(3-azidostyryl)-2'-deoxyuridine 5'-phosphate is a photoactivated inhibitor of thymidylate synthetase.
    De Clercq E; Balzarini J; Chang CT; Bigge CF; Kalaritis P; Mertes MP
    Biochem Biophys Res Commun; 1980 Dec; 97(3):1068-75. PubMed ID: 7470133
    [No Abstract]   [Full Text] [Related]  

  • 18. Metabolic activation of PCBs to quinones: reactivity toward nitrogen and sulfur nucleophiles and influence of superoxide dismutase.
    Amaro AR; Oakley GG; Bauer U; Spielmann HP; Robertson LW
    Chem Res Toxicol; 1996; 9(3):623-9. PubMed ID: 8728508
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis of 5-ethynyl-2'-deoxyuridine-5'-boranomono phosphate as a potential thymidylate synthase inhibitor.
    Khan SI; Dobrikov MI; Shaw BR
    Nucleosides Nucleotides Nucleic Acids; 2005; 24(5-7):1047-9. PubMed ID: 16248089
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 1,4-Reductive addition of glutathione to quinone epoxides. Mechanistic studies with h.p.l.c. with electrochemical detection under anaerobic and aerobic conditions. Evaluation of chemical reactivity in terms of autoxidation reactions.
    Brunmark A; Cadenas E
    Free Radic Biol Med; 1989; 6(2):149-65. PubMed ID: 2707617
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.