BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

202 related articles for article (PubMed ID: 37481821)

  • 1. Widespread dysregulation of mRNA splicing implicates RNA processing in the development and progression of Huntington's disease.
    Tano V; Utami KH; Yusof NABM; Bégin J; Tan WWL; Pouladi MA; Langley SR
    EBioMedicine; 2023 Aug; 94():104720. PubMed ID: 37481821
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Transcriptome sequencing reveals aberrant alternative splicing in Huntington's disease.
    Lin L; Park JW; Ramachandran S; Zhang Y; Tseng YT; Shen S; Waldvogel HJ; Curtis MA; Faull RL; Troncoso JC; Pletnikova O; Ross CA; Davidson BL; Xing Y
    Hum Mol Genet; 2016 Aug; 25(16):3454-3466. PubMed ID: 27378699
    [TBL] [Abstract][Full Text] [Related]  

  • 3. N-terminal mutant huntingtin deposition correlates with CAG repeat length and symptom onset, but not neuronal loss in Huntington's disease.
    Layburn FE; Tan AYS; Mehrabi NF; Curtis MA; Tippett LJ; Turner CP; Riguet N; Aeschbach L; Lashuel HA; Dragunow M; Faull RLM; Singh-Bains MK
    Neurobiol Dis; 2022 Nov; 174():105884. PubMed ID: 36220612
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Deregulated Splicing Is a Major Mechanism of RNA-Induced Toxicity in Huntington's Disease.
    Schilling J; Broemer M; Atanassov I; Duernberger Y; Vorberg I; Dieterich C; Dagane A; Dittmar G; Wanker E; van Roon-Mom W; Winter J; Krauß S
    J Mol Biol; 2019 Apr; 431(9):1869-1877. PubMed ID: 30711541
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A Fresh Look at Huntingtin mRNA Processing in Huntington's Disease.
    Romo L; Mohn ES; Aronin N
    J Huntingtons Dis; 2018; 7(2):101-108. PubMed ID: 29865084
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Co-occurrence of mixed proteinopathies in late-stage Huntington's disease.
    St-Amour I; Turgeon A; Goupil C; Planel E; Hébert SS
    Acta Neuropathol; 2018 Feb; 135(2):249-265. PubMed ID: 29134321
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Huntington's disease-specific mis-splicing unveils key effector genes and altered splicing factors.
    Elorza A; Márquez Y; Cabrera JR; Sánchez-Trincado JL; Santos-Galindo M; Hernández IH; Picó S; Díaz-Hernández JI; García-Escudero R; Irimia M; Lucas JJ
    Brain; 2021 Aug; 144(7):2009-2023. PubMed ID: 33725094
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Downregulation of glial genes involved in synaptic function mitigates Huntington's disease pathogenesis.
    Onur TS; Laitman A; Zhao H; Keyho R; Kim H; Wang J; Mair M; Wang H; Li L; Perez A; de Haro M; Wan YW; Allen G; Lu B; Al-Ramahi I; Liu Z; Botas J
    Elife; 2021 Apr; 10():. PubMed ID: 33871358
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Specific caspase interactions and amplification are involved in selective neuronal vulnerability in Huntington's disease.
    Hermel E; Gafni J; Propp SS; Leavitt BR; Wellington CL; Young JE; Hackam AS; Logvinova AV; Peel AL; Chen SF; Hook V; Singaraja R; Krajewski S; Goldsmith PC; Ellerby HM; Hayden MR; Bredesen DE; Ellerby LM
    Cell Death Differ; 2004 Apr; 11(4):424-38. PubMed ID: 14713958
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Brain urea increase is an early Huntington's disease pathogenic event observed in a prodromal transgenic sheep model and HD cases.
    Handley RR; Reid SJ; Brauning R; Maclean P; Mears ER; Fourie I; Patassini S; Cooper GJS; Rudiger SR; McLaughlan CJ; Verma PJ; Gusella JF; MacDonald ME; Waldvogel HJ; Bawden CS; Faull RLM; Snell RG
    Proc Natl Acad Sci U S A; 2017 Dec; 114(52):E11293-E11302. PubMed ID: 29229845
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Increased Steady-State Mutant Huntingtin mRNA in Huntington's Disease Brain.
    Liu W; Chaurette J; Pfister EL; Kennington LA; Chase KO; Bullock J; Vonsattel JP; Faull RL; Macdonald D; DiFiglia M; Zamore PD; Aronin N
    J Huntingtons Dis; 2013; 2(4):491-500. PubMed ID: 25062733
    [TBL] [Abstract][Full Text] [Related]  

  • 12. RNA Related Pathology in Huntington's Disease.
    Neueder A; Bates GP
    Adv Exp Med Biol; 2018; 1049():85-101. PubMed ID: 29427099
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The pathogenic exon 1 HTT protein is produced by incomplete splicing in Huntington's disease patients.
    Neueder A; Landles C; Ghosh R; Howland D; Myers RH; Faull RLM; Tabrizi SJ; Bates GP
    Sci Rep; 2017 May; 7(1):1307. PubMed ID: 28465506
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Protein changes in synaptosomes of Huntington's disease knock-in mice are dependent on age and brain region.
    Sapp E; Seeley C; Iuliano M; Weisman E; Vodicka P; DiFiglia M; Kegel-Gleason KB
    Neurobiol Dis; 2020 Jul; 141():104950. PubMed ID: 32439598
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Faulty splicing and cytoskeleton abnormalities in Huntington's disease.
    Fernández-Nogales M; Santos-Galindo M; Hernández IH; Cabrera JR; Lucas JJ
    Brain Pathol; 2016 Nov; 26(6):772-778. PubMed ID: 27529534
    [TBL] [Abstract][Full Text] [Related]  

  • 16. RNA toxicity induced by expanded CAG repeats in Huntington's disease.
    Martí E
    Brain Pathol; 2016 Nov; 26(6):779-786. PubMed ID: 27529325
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The dynamics of early-state transcriptional changes and aggregate formation in a Huntington's disease cell model.
    van Hagen M; Piebes DGE; de Leeuw WC; Vuist IM; van Roon-Mom WMC; Moerland PD; Verschure PJ
    BMC Genomics; 2017 May; 18(1):373. PubMed ID: 28499347
    [TBL] [Abstract][Full Text] [Related]  

  • 18. PRMT5- mediated symmetric arginine dimethylation is attenuated by mutant huntingtin and is impaired in Huntington's disease (HD).
    Ratovitski T; Arbez N; Stewart JC; Chighladze E; Ross CA
    Cell Cycle; 2015; 14(11):1716-29. PubMed ID: 25927346
    [TBL] [Abstract][Full Text] [Related]  

  • 19. An alternative splicing modulator decreases mutant HTT and improves the molecular fingerprint in Huntington's disease patient neurons.
    Krach F; Stemick J; Boerstler T; Weiss A; Lingos I; Reischl S; Meixner H; Ploetz S; Farrell M; Hehr U; Kohl Z; Winner B; Winkler J
    Nat Commun; 2022 Nov; 13(1):6797. PubMed ID: 36357392
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Targeting CAG repeat RNAs reduces Huntington's disease phenotype independently of huntingtin levels.
    Rué L; Bañez-Coronel M; Creus-Muncunill J; Giralt A; Alcalá-Vida R; Mentxaka G; Kagerbauer B; Zomeño-Abellán MT; Aranda Z; Venturi V; Pérez-Navarro E; Estivill X; Martí E
    J Clin Invest; 2016 Nov; 126(11):4319-4330. PubMed ID: 27721240
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.