These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
5. An anti-CTLA-4 heavy chain-only antibody with enhanced T Gan X; Shan Q; Li H; Janssens R; Shen Y; He Y; Chen F; van Haperen R; Drabek D; Li J; Zhang Y; Zhao J; Qin B; Jheng MJ; Chen V; Wang J; Rong Y; Grosveld F Proc Natl Acad Sci U S A; 2022 Aug; 119(32):e2200879119. PubMed ID: 35925889 [TBL] [Abstract][Full Text] [Related]
6. Treg depletion inhibits efficacy of cancer immunotherapy: implications for clinical trials. Curtin JF; Candolfi M; Fakhouri TM; Liu C; Alden A; Edwards M; Lowenstein PR; Castro MG PLoS One; 2008 Apr; 3(4):e1983. PubMed ID: 18431473 [TBL] [Abstract][Full Text] [Related]
7. FcγRIIB Is an Immune Checkpoint Limiting the Activity of Treg-Targeting Antibodies in the Tumor Microenvironment. Knorr DA; Blanchard L; Leidner RS; Jensen SM; Meng R; Jones A; Ballesteros-Merino C; Bell RB; Baez M; Marino A; Sprott D; Bifulco CB; Piening B; Dahan R; Osorio JC; Fox BA; Ravetch JV Cancer Immunol Res; 2024 Mar; 12(3):322-333. PubMed ID: 38147316 [TBL] [Abstract][Full Text] [Related]
8. A Neuropilin-1 Antagonist Exerts Antitumor Immunity by Inhibiting the Suppressive Function of Intratumoral Regulatory T Cells. Jung K; Kim JA; Kim YJ; Lee HW; Kim CH; Haam S; Kim YS Cancer Immunol Res; 2020 Jan; 8(1):46-56. PubMed ID: 31554638 [TBL] [Abstract][Full Text] [Related]
9. Anti-CTLA-4 Immunotherapy Does Not Deplete FOXP3 Sharma A; Subudhi SK; Blando J; Scutti J; Vence L; Wargo J; Allison JP; Ribas A; Sharma P Clin Cancer Res; 2019 Feb; 25(4):1233-1238. PubMed ID: 30054281 [TBL] [Abstract][Full Text] [Related]
10. Treg-expressed CTLA-4 depletes CD80/CD86 by trogocytosis, releasing free PD-L1 on antigen-presenting cells. Tekguc M; Wing JB; Osaki M; Long J; Sakaguchi S Proc Natl Acad Sci U S A; 2021 Jul; 118(30):. PubMed ID: 34301886 [TBL] [Abstract][Full Text] [Related]
11. Preclinical development of a novel CCR8/CTLA-4 bispecific antibody for cancer treatment by disrupting CTLA-4 signaling on CD8 T cells and specifically depleting tumor-resident Tregs. Guo C; Dai X; Du Y; Xiong X; Gui X Cancer Immunol Immunother; 2024 Aug; 73(10):210. PubMed ID: 39123089 [TBL] [Abstract][Full Text] [Related]
12. Anti-CTLA-4 antibodies in cancer immunotherapy: selective depletion of intratumoral regulatory T cells or checkpoint blockade? Tang F; Du X; Liu M; Zheng P; Liu Y Cell Biosci; 2018; 8():30. PubMed ID: 29713453 [TBL] [Abstract][Full Text] [Related]
13. Dual targeting of CTLA-4 and CD47 on T Zhang A; Ren Z; Tseng KF; Liu X; Li H; Lu C; Cai Y; Minna JD; Fu YX Sci Transl Med; 2021 Aug; 13(605):. PubMed ID: 34349035 [TBL] [Abstract][Full Text] [Related]
14. Differential control of human Treg and effector T cells in tumor immunity by Fc-engineered anti-CTLA-4 antibody. Ha D; Tanaka A; Kibayashi T; Tanemura A; Sugiyama D; Wing JB; Lim EL; Teng KWW; Adeegbe D; Newell EW; Katayama I; Nishikawa H; Sakaguchi S Proc Natl Acad Sci U S A; 2019 Jan; 116(2):609-618. PubMed ID: 30587582 [TBL] [Abstract][Full Text] [Related]
15. Anti-CTLA-4 antibodies of IgG2a isotype enhance antitumor activity through reduction of intratumoral regulatory T cells. Selby MJ; Engelhardt JJ; Quigley M; Henning KA; Chen T; Srinivasan M; Korman AJ Cancer Immunol Res; 2013 Jul; 1(1):32-42. PubMed ID: 24777248 [TBL] [Abstract][Full Text] [Related]
16. Therapeutic depletion of CCR8 Van Damme H; Dombrecht B; Kiss M; Roose H; Allen E; Van Overmeire E; Kancheva D; Martens L; Murgaski A; Bardet PMR; Blancke G; Jans M; Bolli E; Martins MS; Elkrim Y; Dooley J; Boon L; Schwarze JK; Tacke F; Movahedi K; Vandamme N; Neyns B; Ocak S; Scheyltjens I; Vereecke L; Nana FA; Merchiers P; Laoui D; Van Ginderachter JA J Immunother Cancer; 2021 Feb; 9(2):. PubMed ID: 33589525 [TBL] [Abstract][Full Text] [Related]
17. Intratumoral stem-like CCR4+ regulatory T cells orchestrate the immunosuppressive microenvironment in HCC associated with hepatitis B. Gao Y; You M; Fu J; Tian M; Zhong X; Du C; Hong Z; Zhu Z; Liu J; Markowitz GJ; Wang FS; Yang P J Hepatol; 2022 Jan; 76(1):148-159. PubMed ID: 34689996 [TBL] [Abstract][Full Text] [Related]
18. PD-1 or CTLA-4 blockade promotes CD86-driven Treg responses upon radiotherapy of lymphocyte-depleted cancer in mice. Frijlink E; Bosma DM; Busselaar J; Battaglia TW; Staal MD; Verbrugge I; Borst J J Clin Invest; 2024 Feb; 134(6):. PubMed ID: 38349740 [TBL] [Abstract][Full Text] [Related]
19. Regulatory T Cell Depletion Using a CRISPR Fc-Optimized CD25 Antibody. van Elsas MJ; van der Schoot JMS; Bartels A; Steuten K; van Dalen D; Wijfjes Z; Figdor CG; van Hall T; van der Burg SH; Verdoes M; Scheeren FA Int J Mol Sci; 2022 Aug; 23(15):. PubMed ID: 35955841 [TBL] [Abstract][Full Text] [Related]