BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

131 related articles for article (PubMed ID: 37502910)

  • 1. Intranasal CRMP2-Ubc9 Inhibitor Regulates Na
    Loya-Lopez SI; Allen HN; Duran P; Calderon-Rivera A; Gomez K; Kumar U; Shields R; Zeng R; Dwivedi A; Saurabh S; Korczeniewska OA; Khanna R
    bioRxiv; 2023 Jul; ():. PubMed ID: 37502910
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Intranasal CRMP2-Ubc9 inhibitor regulates Na V 1.7 to alleviate trigeminal neuropathic pain.
    Loya-Lopez SI; Allen HN; Duran P; Calderon-Rivera A; Gomez K; Kumar U; Shields R; Zeng R; Dwivedi A; Saurabh S; Korczeniewska OA; Khanna R
    Pain; 2024 Mar; 165(3):573-588. PubMed ID: 37751532
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of the Ubc9 E2 SUMO-conjugating enzyme-CRMP2 interaction decreases NaV1.7 currents and reverses experimental neuropathic pain.
    François-Moutal L; Dustrude ET; Wang Y; Brustovetsky T; Dorame A; Ju W; Moutal A; Perez-Miller S; Brustovetsky N; Gokhale V; Khanna M; Khanna R
    Pain; 2018 Oct; 159(10):2115-2127. PubMed ID: 29847471
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Small molecule targeting NaV1.7 via inhibition of the CRMP2-Ubc9 interaction reduces and prevents pain chronification in a mouse model of oxaliplatin-induced neuropathic pain.
    Braden K; Stratton HJ; Salvemini D; Khanna R
    Neurobiol Pain; 2022; 11():100082. PubMed ID: 35024498
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Chemical shift perturbation mapping of the Ubc9-CRMP2 interface identifies a pocket in CRMP2 amenable for allosteric modulation of Nav1.7 channels.
    François-Moutal L; Scott DD; Perez-Miller S; Gokhale V; Khanna M; Khanna R
    Channels (Austin); 2018; 12(1):219-227. PubMed ID: 30081699
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cell specific regulation of NaV1.7 activity and trafficking in rat nodose ganglia neurons.
    Loya-López SI; Duran P; Ran D; Calderon-Rivera A; Gomez K; Moutal A; Khanna R
    Neurobiol Pain; 2022; 12():100109. PubMed ID: 36531612
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Targeted transcriptional upregulation of SENP1 by CRISPR activation enhances deSUMOylation pathways to elicit antinociception in the spinal nerve ligation model of neuropathic pain.
    Gomez K; Allen HN; Duran P; Loya-Lopez S; Calderon-Rivera A; Moutal A; Tang C; Nelson TS; Perez-Miller S; Khanna R
    Pain; 2024 Apr; 165(4):866-883. PubMed ID: 37862053
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Non-SUMOylated CRMP2 decreases Na
    Gomez K; Ran D; Madura CL; Moutal A; Khanna R
    Mol Brain; 2021 Jan; 14(1):20. PubMed ID: 33478555
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Kv4.3 Channel Dysfunction Contributes to Trigeminal Neuropathic Pain Manifested with Orofacial Cold Hypersensitivity in Rats.
    Kanda H; Ling J; Chang YT; Erol F; Viatchenko-Karpinski V; Yamada A; Noguchi K; Gu JG
    J Neurosci; 2021 Mar; 41(10):2091-2105. PubMed ID: 33472822
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Studies on CRMP2 SUMOylation-deficient transgenic mice identify sex-specific Nav1.7 regulation in the pathogenesis of chronic neuropathic pain.
    Moutal A; Cai S; Yu J; Stratton HJ; Chefdeville A; Gomez K; Ran D; Madura CL; Boinon L; Soto M; Zhou Y; Shan Z; Chew LA; Rodgers KE; Khanna R
    Pain; 2020 Nov; 161(11):2629-2651. PubMed ID: 32569093
    [TBL] [Abstract][Full Text] [Related]  

  • 11. SUMOylation alters CRMP2 regulation of calcium influx in sensory neurons.
    Ju W; Li Q; Wilson SM; Brittain JM; Meroueh L; Khanna R
    Channels (Austin); 2013; 7(3):153-9. PubMed ID: 23510938
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Small molecule targeting NaV1.7 via inhibition of the CRMP2-Ubc9 interaction reduces pain in chronic constriction injury (CCI) rats.
    Li J; Stratton HJ; Lorca SA; Grace PM; Khanna R
    Channels (Austin); 2022 Dec; 16(1):1-8. PubMed ID: 34983286
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cdk5-mediated CRMP2 phosphorylation is necessary and sufficient for peripheral neuropathic pain.
    Moutal A; Luo S; Largent-Milnes TM; Vanderah TW; Khanna R
    Neurobiol Pain; 2019; 5():. PubMed ID: 31080913
    [TBL] [Abstract][Full Text] [Related]  

  • 14. TNF-α mediated upregulation of Na
    de Macedo FHP; Aires RD; Fonseca EG; Ferreira RCM; Machado DPD; Chen L; Zhang FX; Souza IA; Lemos VS; Romero TRL; Moutal A; Khanna R; Zamponi GW; Cruz JS
    Mol Brain; 2019 Dec; 12(1):117. PubMed ID: 31888677
    [TBL] [Abstract][Full Text] [Related]  

  • 15. CRMP2 protein SUMOylation modulates NaV1.7 channel trafficking.
    Dustrude ET; Wilson SM; Ju W; Xiao Y; Khanna R
    J Biol Chem; 2013 Aug; 288(34):24316-31. PubMed ID: 23836888
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Phosphorylated CRMP2 Regulates Spinal Nociceptive Neurotransmission.
    Yu J; Moutal A; Dorame A; Bellampalli SS; Chefdeville A; Kanazawa I; Pham NYN; Park KD; Weimer JM; Khanna R
    Mol Neurobiol; 2019 Jul; 56(7):5241-5255. PubMed ID: 30565051
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Homology-guided mutational analysis reveals the functional requirements for antinociceptive specificity of collapsin response mediator protein 2-derived peptides.
    Moutal A; Li W; Wang Y; Ju W; Luo S; Cai S; François-Moutal L; Perez-Miller S; Hu J; Dustrude ET; Vanderah TW; Gokhale V; Khanna M; Khanna R
    Br J Pharmacol; 2018 Jun; 175(12):2244-2260. PubMed ID: 28161890
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Sustained relief of ongoing experimental neuropathic pain by a CRMP2 peptide aptamer with low abuse potential.
    Xie JY; Chew LA; Yang X; Wang Y; Qu C; Wang Y; Federici LM; Fitz SD; Ripsch MS; Due MR; Moutal A; Khanna M; White FA; Vanderah TW; Johnson PL; Porreca F; Khanna R
    Pain; 2016 Sep; 157(9):2124-2140. PubMed ID: 27537210
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Hierarchical CRMP2 posttranslational modifications control NaV1.7 function.
    Dustrude ET; Moutal A; Yang X; Wang Y; Khanna M; Khanna R
    Proc Natl Acad Sci U S A; 2016 Dec; 113(52):E8443-E8452. PubMed ID: 27940916
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Dissecting the role of the CRMP2-neurofibromin complex on pain behaviors.
    Moutal A; Wang Y; Yang X; Ji Y; Luo S; Dorame A; Bellampalli SS; Chew LA; Cai S; Dustrude ET; Keener JE; Marty MT; Vanderah TW; Khanna R
    Pain; 2017 Nov; 158(11):2203-2221. PubMed ID: 28767512
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.