BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

177 related articles for article (PubMed ID: 37509605)

  • 41. Induction of p53 expression and apoptosis by a recombinant dual-target MDM2/MDMX inhibitory protein in wild-type p53 breast cancer cells.
    Geng QQ; Dong DF; Chen NZ; Wu YY; Li EX; Wang J; Wang SM
    Int J Oncol; 2013 Dec; 43(6):1935-42. PubMed ID: 24126697
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Therapeutic opportunities in cancer therapy: targeting the p53-MDM2/MDMX interactions.
    Munisamy M; Mukherjee N; Thomas L; Pham AT; Shakeri A; Zhao Y; Kolesar J; Rao PPN; Rangnekar VM; Rao M
    Am J Cancer Res; 2021; 11(12):5762-5781. PubMed ID: 35018225
    [TBL] [Abstract][Full Text] [Related]  

  • 43. The MDM4/MDM2-p53-IGF1 axis controls axonal regeneration, sprouting and functional recovery after CNS injury.
    Joshi Y; Sória MG; Quadrato G; Inak G; Zhou L; Hervera A; Rathore KI; Elnaggar M; Cucchiarini M; Marine JC; Puttagunta R; Di Giovanni S
    Brain; 2015 Jul; 138(Pt 7):1843-62. PubMed ID: 25981963
    [TBL] [Abstract][Full Text] [Related]  

  • 44. NDRG4 is a novel oncogenic protein and p53 associated regulator of apoptosis in malignant meningioma cells.
    Kotipatruni RP; Ren X; Thotala D; Jaboin JJ
    Oncotarget; 2015 Jul; 6(19):17594-604. PubMed ID: 26053091
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Mdm2 Splice isoforms regulate the p53/Mdm2/Mdm4 regulatory circuit via RING domain-mediated ubiquitination of p53 and Mdm4.
    Fan C; Wang X
    Cell Cycle; 2017 Apr; 16(7):660-664. PubMed ID: 28166445
    [TBL] [Abstract][Full Text] [Related]  

  • 46. The MDM2 Inhibitor Navtemadlin Arrests Mouse Melanoma Growth
    Ingelshed K; Spiegelberg D; Kannan P; Påvénius L; Hacheney J; Jiang L; Eisinger S; Lianoudaki D; Lama D; Castillo F; Bosdotter C; Kretzschmar WW; Al-Radi O; Fritz N; Villablanca EJ; Karlsson MCI; Wermeling F; Nestor M; Lane DP; Sedimbi SK
    Cancer Res Commun; 2022 Sep; 2(9):1075-1088. PubMed ID: 36922937
    [TBL] [Abstract][Full Text] [Related]  

  • 47. The long and the short of it: the MDM4 tail so far.
    Haupt S; Mejía-Hernández JO; Vijayakumaran R; Keam SP; Haupt Y
    J Mol Cell Biol; 2019 Mar; 11(3):231-244. PubMed ID: 30689920
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Mdm4 (Mdmx) regulates p53-induced growth arrest and neuronal cell death during early embryonic mouse development.
    Migliorini D; Lazzerini Denchi E; Danovi D; Jochemsen A; Capillo M; Gobbi A; Helin K; Pelicci PG; Marine JC
    Mol Cell Biol; 2002 Aug; 22(15):5527-38. PubMed ID: 12101245
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Regulation of MDM4.
    Markey MP
    Front Biosci (Landmark Ed); 2011 Jan; 16(3):1144-56. PubMed ID: 21196223
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Mdm2 and Mdm4 loss regulates distinct p53 activities.
    Barboza JA; Iwakuma T; Terzian T; El-Naggar AK; Lozano G
    Mol Cancer Res; 2008 Jun; 6(6):947-54. PubMed ID: 18567799
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Downregulation of microRNA-23b protects against ischemia-reperfusion injury via p53 signaling pathway by upregulating MDM4 in rats.
    Zhao Z; Guan JZ; Wu M; Lai GH; Zhu ZL
    J Cell Biochem; 2019 Mar; 120(3):4599-4612. PubMed ID: 30537038
    [TBL] [Abstract][Full Text] [Related]  

  • 52. miR-661 downregulates both Mdm2 and Mdm4 to activate p53.
    Hoffman Y; Bublik DR; Pilpel Y; Oren M
    Cell Death Differ; 2014 Feb; 21(2):302-9. PubMed ID: 24141721
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Synergistic regulation of p53 by Mdm2 and Mdm4 is critical in cardiac endocardial cushion morphogenesis during heart development.
    Zhang Q; He X; Chen L; Zhang C; Gao X; Yang Z; Liu G
    J Pathol; 2012 Nov; 228(3):416-28. PubMed ID: 22821713
    [TBL] [Abstract][Full Text] [Related]  

  • 54. MDM4 (MDMX) overexpression enhances stabilization of stress-induced p53 and promotes apoptosis.
    Mancini F; Gentiletti F; D'Angelo M; Giglio S; Nanni S; D'Angelo C; Farsetti A; Citro G; Sacchi A; Pontecorvi A; Moretti F
    J Biol Chem; 2004 Feb; 279(9):8169-80. PubMed ID: 14660608
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Pharmacological activation of the p53 pathway by nutlin-3 exerts anti-tumoral effects in medulloblastomas.
    Künkele A; De Preter K; Heukamp L; Thor T; Pajtler KW; Hartmann W; Mittelbronn M; Grotzer MA; Deubzer HE; Speleman F; Schramm A; Eggert A; Schulte JH
    Neuro Oncol; 2012 Jul; 14(7):859-69. PubMed ID: 22591662
    [TBL] [Abstract][Full Text] [Related]  

  • 56. MDM4 alternative splicing and implication in MDM4 targeted cancer therapies.
    Wu J; Lu G; Wang X
    Am J Cancer Res; 2021; 11(12):5864-5880. PubMed ID: 35018230
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Mdm4 loss in mice expressing a p53 hypomorph alters tumor spectrum without improving survival.
    Fang M; Simeonova I; Bardot B; Lejour V; Jaber S; Bouarich-Bourimi R; Morin A; Toledo F
    Oncogene; 2014 Mar; 33(10):1336-9. PubMed ID: 23474762
    [TBL] [Abstract][Full Text] [Related]  

  • 58. MDM4 is a key therapeutic target in cutaneous melanoma.
    Gembarska A; Luciani F; Fedele C; Russell EA; Dewaele M; Villar S; Zwolinska A; Haupt S; de Lange J; Yip D; Goydos J; Haigh JJ; Haupt Y; Larue L; Jochemsen A; Shi H; Moriceau G; Lo RS; Ghanem G; Shackleton M; Bernal F; Marine JC
    Nat Med; 2012 Aug; 18(8):1239-47. PubMed ID: 22820643
    [TBL] [Abstract][Full Text] [Related]  

  • 59. The expression of MDM2, MDM4, p53 and p21 in myeloid neoplasms and the effect of MDM2/MDM4 dual inhibitor.
    Eskandari M; Shi Y; Liu J; Albanese J; Goel S; Verma A; Wang Y
    Leuk Lymphoma; 2021 Jan; 62(1):167-175. PubMed ID: 32924682
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Methylation of p14(ARF) gene in meningiomas and its correlation to the p53 expression and mutation.
    Amatya VJ; Takeshima Y; Inai K
    Mod Pathol; 2004 Jun; 17(6):705-10. PubMed ID: 15073599
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 9.