BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

129 related articles for article (PubMed ID: 37536263)

  • 21. "Selective" Class C G Protein-Coupled Receptor Modulators Are Neutral or Biased mGlu
    Hellyer SD; Albold S; Wang T; Chen ANY; May LT; Leach K; Gregory KJ
    Mol Pharmacol; 2018 May; 93(5):504-514. PubMed ID: 29514854
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Characterization of a New Positive Allosteric Modulator of AMPA Receptors - PAM-43: Specific Binding of the Ligand and its Ability to Potentiate AMPAR Currents.
    Vyunova TV; Andreeva LA; Shevchenko KV; Grigoriev VV; Palyulin VA; Lavrov MI; Bondarenko EV; Kalashnikova EE; Myasoedov NF
    Curr Mol Pharmacol; 2020; 13(3):216-223. PubMed ID: 32124706
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Discovery and characterization of 2-(cyclopropanesulfonamido)-N-(2-ethoxyphenyl)benzamide, ML382: a potent and selective positive allosteric modulator of MrgX1.
    Wen W; Wang Y; Li Z; Tseng PY; McManus OB; Wu M; Li M; Lindsley CW; Dong X; Hopkins CR
    ChemMedChem; 2015 Jan; 10(1):57-61. PubMed ID: 25209672
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Marine Bile Natural Products as Agonists of the TGR5 Receptor.
    Halkias C; Darby WG; Feltis BN; McIntyre P; Macrides TA; Wright PFA
    J Nat Prod; 2021 May; 84(5):1507-1514. PubMed ID: 33904732
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Pharmacological and molecular characterization of the positive allosteric modulators of metabotropic glutamate receptor 2.
    Lundström L; Bissantz C; Beck J; Dellenbach M; Woltering TJ; Wichmann J; Gatti S
    Neuropharmacology; 2016 Dec; 111():253-265. PubMed ID: 27590915
    [TBL] [Abstract][Full Text] [Related]  

  • 26. TGR5 contributes to hepatic cystogenesis in rodents with polycystic liver diseases through cyclic adenosine monophosphate/Gαs signaling.
    Masyuk TV; Masyuk AI; Lorenzo Pisarello M; Howard BN; Huang BQ; Lee PY; Fung X; Sergienko E; Ardecky RJ; Chung TDY; Pinkerton AB; LaRusso NF
    Hepatology; 2017 Oct; 66(4):1197-1218. PubMed ID: 28543567
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Identification of Novel Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 5 Acting at Site Distinct from 2-Methyl-6-(phenylethynyl)-pyridine Binding.
    Butkiewicz M; Rodriguez AL; Rainey SE; Wieting J; Luscombe VB; Stauffer SR; Lindsley CW; Conn PJ; Meiler J
    ACS Chem Neurosci; 2019 Aug; 10(8):3427-3436. PubMed ID: 31132237
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Development of Selective TGR5 Ligands Based on the 5,6,7,8-Tetrahydro-5,5,8,8-tetramethylnaphthalene Skeleton.
    Terui R; Yanase Y; Yokoo H; Suhara Y; Makishima M; Demizu Y; Misawa T
    ChemMedChem; 2021 Feb; 16(3):458-462. PubMed ID: 32969181
    [TBL] [Abstract][Full Text] [Related]  

  • 29. TGR5 activation induces cytoprotective changes in the heart and improves myocardial adaptability to physiologic, inotropic, and pressure-induced stress in mice.
    Eblimit Z; Thevananther S; Karpen SJ; Taegtmeyer H; Moore DD; Adorini L; Penny DJ; Desai MS
    Cardiovasc Ther; 2018 Oct; 36(5):e12462. PubMed ID: 30070769
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Reprint of Pharmacological and molecular characterization of the positive allosteric modulators of metabotropic glutamate receptor 2.
    Lundström L; Bissantz C; Beck J; Dellenbach M; Woltering TJ; Wichmann J; Gatti S
    Neuropharmacology; 2017 Mar; 115():115-127. PubMed ID: 28216000
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Positive Allosteric Modulators of Metabotropic Glutamate Receptor 5 as Tool Compounds to Study Signaling Bias.
    Arsova A; Møller TC; Hellyer SD; Vedel L; Foster SR; Hansen JL; Bräuner-Osborne H; Gregory KJ
    Mol Pharmacol; 2021 May; 99(5):328-341. PubMed ID: 33602724
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Discovery of betulinic acid derivatives as gut-restricted TGR5 agonists: Balancing the potency and physicochemical properties.
    Zhuo N; Yun Y; Zhang C; Guo S; Yin J; Zhao T; Ge X; Gu M; Xie X; Nan F
    Bioorg Chem; 2024 Mar; 144():107132. PubMed ID: 38241768
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Design, synthesis and evaluation of 1-benzyl-1H-imidazole-5-carboxamide derivatives as potent TGR5 agonists.
    Zhao S; Li X; Wang L; Peng W; Ye W; Li W; Wang YD; Chen WD
    Bioorg Med Chem; 2021 Feb; 32():115972. PubMed ID: 33440321
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Bile Acid G Protein-Coupled Membrane Receptor TGR5 Modulates Aquaporin 2-Mediated Water Homeostasis.
    Li S; Qiu M; Kong Y; Zhao X; Choi HJ; Reich M; Bunkelman BH; Liu Q; Hu S; Han M; Xie H; Rosenberg AZ; Keitel V; Kwon TH; Levi M; Li C; Wang W
    J Am Soc Nephrol; 2018 Nov; 29(11):2658-2670. PubMed ID: 30305310
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Design, synthesis and evaluation of unnatural peptides as T1R2/T1R3 PAMs.
    Yamada K; Matsumoto R; Suzuki Y; Mori S; Kitajima S
    Bioorg Med Chem Lett; 2020 Apr; 30(8):127000. PubMed ID: 32063432
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Multigenerational impacts of bile exposure are mediated by TGR5 signaling pathways.
    Baptissart M; Sèdes L; Holota H; Thirouard L; Martinot E; de Haze A; Rouaisnel B; Caira F; Beaudoin C; Volle DH
    Sci Rep; 2018 Nov; 8(1):16875. PubMed ID: 30443025
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Allspice and Clove As Source of Triterpene Acids Activating the G Protein-Coupled Bile Acid Receptor TGR5.
    Ladurner A; Zehl M; Grienke U; Hofstadler C; Faur N; Pereira FC; Berry D; Dirsch VM; Rollinger JM
    Front Pharmacol; 2017; 8():468. PubMed ID: 28769799
    [TBL] [Abstract][Full Text] [Related]  

  • 38. INT-777 prevents cognitive impairment by activating Takeda G protein-coupled receptor 5 (TGR5) and attenuating neuroinflammation via cAMP/ PKA/ CREB signaling axis in a rat model of sepsis.
    Jin P; Deng S; Tian M; Lenahan C; Wei P; Wang Y; Tan J; Wen H; Zhao F; Gao Y; Gong Y
    Exp Neurol; 2021 Jan; 335():113504. PubMed ID: 33058889
    [TBL] [Abstract][Full Text] [Related]  

  • 39. TGR5 controls bile acid composition and gallbladder function to protect the liver from bile acid overload.
    Bidault-Jourdainne V; Merlen G; Glénisson M; Doignon I; Garcin I; Péan N; Boisgard R; Ursic-Bedoya J; Serino M; Ullmer C; Humbert L; Abdelrafee A; Golse N; Vibert E; Duclos-Vallée JC; Rainteau D; Tordjmann T
    JHEP Rep; 2021 Apr; 3(2):100214. PubMed ID: 33604531
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Synthesis and biological evaluation of a new series of 2-amino-3-aroyl thiophene derivatives as agonist allosteric modulators of the A1 adenosine receptor. A position-dependent effect study.
    Romagnoli R; Baraldi PG; Lopez-Cara C; Cruz-Lopez O; Moorman AR; Massink A; IJzerman AP; Vincenzi F; Borea PA; Varani K
    Eur J Med Chem; 2015 Aug; 101():185-204. PubMed ID: 26141910
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 7.