BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

139 related articles for article (PubMed ID: 37536521)

  • 1. Preomic profile of BxPC-3 cells after treatment with BRC4.
    Previtali V; Myers SH; Poppi L; Wynne K; Casamassima I; Girotto S; Di Stefano G; Farabegoli F; Roberti M; Oliviero G; Cavalli A
    J Proteomics; 2023 Sep; 288():104983. PubMed ID: 37536521
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The Mechanistic Understanding of RAD51 Defibrillation: A Critical Step in BRCA2-Mediated DNA Repair by Homologous Recombination.
    Schipani F; Manerba M; Marotta R; Poppi L; Gennari A; Rinaldi F; Armirotti A; Farabegoli F; Roberti M; Di Stefano G; Rocchia W; Girotto S; Tirelli N; Cavalli A
    Int J Mol Sci; 2022 Jul; 23(15):. PubMed ID: 35955488
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A Short BRCA2-Derived Cell-Penetrating Peptide Targets RAD51 Function and Confers Hypersensitivity toward PARP Inhibition.
    Trenner A; Godau J; Sartori AA
    Mol Cancer Ther; 2018 Jul; 17(7):1392-1404. PubMed ID: 29654063
    [TBL] [Abstract][Full Text] [Related]  

  • 4. High levels of BRC4 induced by a Tet-On 3G system suppress DNA repair and impair cell proliferation in vertebrate cells.
    Abe T; Branzei D
    DNA Repair (Amst); 2014 Oct; 22():153-64. PubMed ID: 25218467
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Contributions of the RAD51 N-terminal domain to BRCA2-RAD51 interaction.
    Subramanyam S; Jones WT; Spies M; Spies MA
    Nucleic Acids Res; 2013 Oct; 41(19):9020-32. PubMed ID: 23935068
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Double-stranded DNA binding function of RAD51 in DNA protection and its regulation by BRCA2.
    Halder S; Sanchez A; Ranjha L; Reginato G; Ceppi I; Acharya A; Anand R; Cejka P
    Mol Cell; 2022 Oct; 82(19):3553-3565.e5. PubMed ID: 36070766
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Rad51/BRCA2 disruptors inhibit homologous recombination and synergize with olaparib in pancreatic cancer cells.
    Roberti M; Schipani F; Bagnolini G; Milano D; Giacomini E; Falchi F; Balboni A; Manerba M; Farabegoli F; De Franco F; Robertson J; Minucci S; Pallavicini I; Di Stefano G; Girotto S; Pellicciari R; Cavalli A
    Eur J Med Chem; 2019 Mar; 165():80-92. PubMed ID: 30660828
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Design, synthesis, and characterization of BRC4 mutants based on the crystal structure of BRC4-RAD51(191-220).
    Zhao D; Lu K
    J Mol Model; 2015 Nov; 21(11):299. PubMed ID: 26522863
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design, synthesis and interaction of BRC4 analogous peptides with RAD51(241-260).
    Li J; Lu K; Lv M; Liu G; Ma L; Qi J
    Amino Acids; 2020 Mar; 52(3):361-369. PubMed ID: 31875260
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthetic Lethality in Pancreatic Cancer: Discovery of a New RAD51-BRCA2 Small Molecule Disruptor That Inhibits Homologous Recombination and Synergizes with Olaparib.
    Bagnolini G; Milano D; Manerba M; Schipani F; Ortega JA; Gioia D; Falchi F; Balboni A; Farabegoli F; De Franco F; Robertson J; Pellicciari R; Pallavicini I; Peri S; Minucci S; Girotto S; Di Stefano G; Roberti M; Cavalli A
    J Med Chem; 2020 Mar; 63(5):2588-2619. PubMed ID: 32037829
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Interrogation of the protein-protein interactions between human BRCA2 BRC repeats and RAD51 reveals atomistic determinants of affinity.
    Cole DJ; Rajendra E; Roberts-Thomson M; Hardwick B; McKenzie GJ; Payne MC; Venkitaraman AR; Skylaris CK
    PLoS Comput Biol; 2011 Jul; 7(7):e1002096. PubMed ID: 21789034
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cancer-associated mutations in BRC domains of BRCA2 affect homologous recombination induced by Rad51.
    Tal A; Arbel-Goren R; Stavans J
    J Mol Biol; 2009 Nov; 393(5):1007-12. PubMed ID: 19747923
    [TBL] [Abstract][Full Text] [Related]  

  • 13. BRCA2 BRC motifs bind RAD51-DNA filaments.
    Galkin VE; Esashi F; Yu X; Yang S; West SC; Egelman EH
    Proc Natl Acad Sci U S A; 2005 Jun; 102(24):8537-42. PubMed ID: 15937124
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The BRC repeats of BRCA2 modulate the DNA-binding selectivity of RAD51.
    Carreira A; Hilario J; Amitani I; Baskin RJ; Shivji MK; Venkitaraman AR; Kowalczykowski SC
    Cell; 2009 Mar; 136(6):1032-43. PubMed ID: 19303847
    [TBL] [Abstract][Full Text] [Related]  

  • 15. BRCA2 regulates DMC1-mediated recombination through the BRC repeats.
    Martinez JS; von Nicolai C; Kim T; Ehlén Å; Mazin AV; Kowalczykowski SC; Carreira A
    Proc Natl Acad Sci U S A; 2016 Mar; 113(13):3515-20. PubMed ID: 26976601
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identification of deleterious variants of uncertain significance in BRCA2 BRC4 repeat through molecular dynamics simulations.
    Sinha S; Qin Z; Tam B; Wang SM
    Brief Funct Genomics; 2022 May; 21(3):202-215. PubMed ID: 35325018
    [TBL] [Abstract][Full Text] [Related]  

  • 17. DNA binding and RAD51 engagement by the BRCA2 C-terminus orchestrate DNA repair and replication fork preservation.
    Kwon Y; Rösner H; Zhao W; Selemenakis P; He Z; Kawale AS; Katz JN; Rogers CM; Neal FE; Badamchi Shabestari A; Petrosius V; Singh AK; Joel MZ; Lu L; Holloway SP; Burma S; Mukherjee B; Hromas R; Mazin A; Wiese C; Sørensen CS; Sung P
    Nat Commun; 2023 Jan; 14(1):432. PubMed ID: 36702902
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Fanconi anemia complementation group D2 (FANCD2) functions independently of BRCA2- and RAD51-associated homologous recombination in response to DNA damage.
    Ohashi A; Zdzienicka MZ; Chen J; Couch FJ
    J Biol Chem; 2005 Apr; 280(15):14877-83. PubMed ID: 15671039
    [TBL] [Abstract][Full Text] [Related]  

  • 19. An
    Myers SH; Poppi L; Rinaldi F; Veronesi M; Ciamarone A; Previtali V; Bagnolini G; Schipani F; Ortega Martínez JA; Girotto S; Di Stefano G; Farabegoli F; Walsh N; De Franco F; Roberti M; Cavalli A
    Eur J Med Chem; 2024 Feb; 265():116114. PubMed ID: 38194775
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Valine 1532 of human BRC repeat 4 plays an important role in the interaction between BRCA2 and RAD51.
    Ochiai K; Yoshikawa Y; Yoshimatsu K; Oonuma T; Tomioka Y; Takeda E; Arikawa J; Mominoki K; Omi T; Hashizume K; Morimatsu M
    FEBS Lett; 2011 Jun; 585(12):1771-7. PubMed ID: 21601571
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.