BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

159 related articles for article (PubMed ID: 37541375)

  • 1. Platycodin D induces apoptotic cell death through PI3K/AKT and MAPK/ERK pathways and synergizes with venetoclax in acute myeloid leukemia.
    Jiang X; Lin Y; Zhao M; Li Y; Ye P; Pei R; Lu Y; Jiang L
    Eur J Pharmacol; 2023 Oct; 956():175957. PubMed ID: 37541375
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Platycodin D inhibits migration, invasion, and growth of MDA-MB-231 human breast cancer cells via suppression of EGFR-mediated Akt and MAPK pathways.
    Chun J; Kim YS
    Chem Biol Interact; 2013 Oct; 205(3):212-21. PubMed ID: 23867902
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Induction of apoptosis through inactivation of ROS-dependent PI3K/Akt signaling pathway by platycodin D in human bladder urothelial carcinoma cells.
    Park C; Cha HJ; Lee H; Jeong JW; Han M; Song KS; Kim GY; Chang YC; Leem SH; Hyun JW; Kim HS; Hong SH; Choi YH
    Gen Physiol Biophys; 2022 Jul; 41(4):263-274. PubMed ID: 35938960
    [TBL] [Abstract][Full Text] [Related]  

  • 4. MEK/ERK and PI3K/AKT pathway inhibitors affect the transformation of myelodysplastic syndrome into acute myeloid leukemia via H3K27me3 methylases and de‑methylases.
    Zheng Z; Chen X; Zhang Y; Ren F; Ma Y
    Int J Oncol; 2023 Dec; 63(6):. PubMed ID: 37921060
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Rationale for Combining the BCL2 Inhibitor Venetoclax with the PI3K Inhibitor Bimiralisib in the Treatment of IDH2- and FLT3-Mutated Acute Myeloid Leukemia.
    Seipel K; Brügger Y; Mandhair H; Bacher U; Pabst T
    Int J Mol Sci; 2022 Oct; 23(20):. PubMed ID: 36293442
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Platycodin D, a triterpenoid saponin from Platycodon grandiflorum, induces G2/M arrest and apoptosis in human hepatoma HepG2 cells by modulating the PI3K/Akt pathway.
    Qin H; Du X; Zhang Y; Wang R
    Tumour Biol; 2014 Feb; 35(2):1267-74. PubMed ID: 24048756
    [TBL] [Abstract][Full Text] [Related]  

  • 7. IκB kinase overcomes PI3K/Akt and ERK/MAPK to control FOXO3a activity in acute myeloid leukemia.
    Chapuis N; Park S; Leotoing L; Tamburini J; Verdier F; Bardet V; Green AS; Willems L; Agou F; Ifrah N; Dreyfus F; Bismuth G; Baud V; Lacombe C; Mayeux P; Bouscary D
    Blood; 2010 Nov; 116(20):4240-50. PubMed ID: 20671123
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Icaritin induces AML cell apoptosis via the MAPK/ERK and PI3K/AKT signal pathways.
    Li Q; Huai L; Zhang C; Wang C; Jia Y; Chen Y; Yu P; Wang H; Rao Q; Wang M; Wang J
    Int J Hematol; 2013 May; 97(5):617-23. PubMed ID: 23550021
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of Bcl-2 Synergistically Enhances the Antileukemic Activity of Midostaurin and Gilteritinib in Preclinical Models of FLT3-Mutated Acute Myeloid Leukemia.
    Ma J; Zhao S; Qiao X; Knight T; Edwards H; Polin L; Kushner J; Dzinic SH; White K; Wang G; Zhao L; Lin H; Wang Y; Taub JW; Ge Y
    Clin Cancer Res; 2019 Nov; 25(22):6815-6826. PubMed ID: 31320594
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Platycodin D triggers autophagy through activation of extracellular signal-regulated kinase in hepatocellular carcinoma HepG2 cells.
    Li T; Tang ZH; Xu WS; Wu GS; Wang YF; Chang LL; Zhu H; Chen XP; Wang YT; Chen Y; Lu JJ
    Eur J Pharmacol; 2015 Feb; 749():81-8. PubMed ID: 25592318
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Oridonin Synergistically Enhances the Pro-Apoptotic Effect of Venetoclax on Acute Myeloid Leukemia Cells by Inhibiting AKT Signaling.
    Chen L; Li D; Guo X; Cheng C; Wei X
    Front Biosci (Landmark Ed); 2023 Sep; 28(9):195. PubMed ID: 37796705
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Platycodin D induces proliferation inhibition and mitochondrial apoptosis in diffuse large B-cell lymphoma.
    Liu P; Zhao M; Lin Y; Jiang X; Xia T; Li Y; Lu Y; Jiang L
    Exp Hematol; 2023 Jul; 123():46-55.e1. PubMed ID: 37085039
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Sinodielide A exerts thermosensitizing effects and induces apoptosis and G2/M cell cycle arrest in DU145 human prostate cancer cells via the Ras/Raf/MAPK and PI3K/Akt signaling pathways.
    Hatashita M; Taniguchi M; Baba K; Koshiba K; Sato T; Jujo Y; Suzuki R; Hayashi S
    Int J Mol Med; 2014 Feb; 33(2):406-14. PubMed ID: 24285252
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A combination of temsirolimus, an allosteric mTOR inhibitor, with clofarabine as a new therapeutic option for patients with acute myeloid leukemia.
    Chiarini F; Lonetti A; Teti G; Orsini E; Bressanin D; Cappellini A; Ricci F; Tazzari PL; Ognibene A; Falconi M; Pagliaro P; Iacobucci I; Martinelli G; Amadori S; McCubrey JA; Martelli AM
    Oncotarget; 2012 Dec; 3(12):1615-28. PubMed ID: 23271044
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Dual inhibition of Bcl-2 and Bcl-xL strikingly enhances PI3K inhibition-induced apoptosis in human myeloid leukemia cells through a GSK3- and Bim-dependent mechanism.
    Rahmani M; Aust MM; Attkisson E; Williams DC; Ferreira-Gonzalez A; Grant S
    Cancer Res; 2013 Feb; 73(4):1340-51. PubMed ID: 23243017
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The BH3-only protein Bim plays a critical role in leukemia cell death triggered by concomitant inhibition of the PI3K/Akt and MEK/ERK1/2 pathways.
    Rahmani M; Anderson A; Habibi JR; Crabtree TR; Mayo M; Harada H; Ferreira-Gonzalez A; Dent P; Grant S
    Blood; 2009 Nov; 114(20):4507-16. PubMed ID: 19773546
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Effects of platycodin D on proliferation, apoptosis and PI3K/Akt signal pathway of human glioma U251 cells.
    Xu C; Sun G; Yuan G; Wang R; Sun X
    Molecules; 2014 Dec; 19(12):21411-23. PubMed ID: 25532840
    [TBL] [Abstract][Full Text] [Related]  

  • 18. SYK regulates mTOR signaling in AML.
    Carnevale J; Ross L; Puissant A; Banerji V; Stone RM; DeAngelo DJ; Ross KN; Stegmaier K
    Leukemia; 2013 Nov; 27(11):2118-28. PubMed ID: 23535559
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Licochalcone A induces mitochondria-dependent apoptosis and interacts with venetoclax in acute myeloid leukemia.
    Li Y; Zhao M; Lin Y; Jiang X; Jin L; Ye P; Lu Y; Pei R; Jiang L
    Eur J Pharmacol; 2024 Apr; 968():176418. PubMed ID: 38350590
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cotargeting BCL-2 and PI3K Induces BAX-Dependent Mitochondrial Apoptosis in AML Cells.
    Rahmani M; Nkwocha J; Hawkins E; Pei X; Parker RE; Kmieciak M; Leverson JD; Sampath D; Ferreira-Gonzalez A; Grant S
    Cancer Res; 2018 Jun; 78(11):3075-3086. PubMed ID: 29559471
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.