These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

217 related articles for article (PubMed ID: 37549289)

  • 1. FAN1 removes triplet repeat extrusions via a PCNA- and RFC-dependent mechanism.
    Phadte AS; Bhatia M; Ebert H; Abdullah H; Elrazaq EA; Komolov KE; Pluciennik A
    Proc Natl Acad Sci U S A; 2023 Aug; 120(33):e2302103120. PubMed ID: 37549289
    [TBL] [Abstract][Full Text] [Related]  

  • 2. FAN1 controls mismatch repair complex assembly via MLH1 retention to stabilize CAG repeat expansion in Huntington's disease.
    Goold R; Hamilton J; Menneteau T; Flower M; Bunting EL; Aldous SG; Porro A; Vicente JR; Allen ND; Wilkinson H; Bates GP; Sartori AA; Thalassinos K; Balmus G; Tabrizi SJ
    Cell Rep; 2021 Aug; 36(9):109649. PubMed ID: 34469738
    [TBL] [Abstract][Full Text] [Related]  

  • 3. FAN1 exo- not endo-nuclease pausing on disease-associated slipped-DNA repeats: A mechanism of repeat instability.
    Deshmukh AL; Caron MC; Mohiuddin M; Lanni S; Panigrahi GB; Khan M; Engchuan W; Shum N; Faruqui A; Wang P; Yuen RKC; Nakamori M; Nakatani K; Masson JY; Pearson CE
    Cell Rep; 2021 Dec; 37(10):110078. PubMed ID: 34879276
    [TBL] [Abstract][Full Text] [Related]  

  • 4. FAN1 modifies Huntington's disease progression by stabilizing the expanded HTT CAG repeat.
    Goold R; Flower M; Moss DH; Medway C; Wood-Kaczmar A; Andre R; Farshim P; Bates GP; Holmans P; Jones L; Tabrizi SJ
    Hum Mol Genet; 2019 Feb; 28(4):650-661. PubMed ID: 30358836
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Promotion of somatic CAG repeat expansion by Fan1 knock-out in Huntington's disease knock-in mice is blocked by Mlh1 knock-out.
    Loupe JM; Pinto RM; Kim KH; Gillis T; Mysore JS; Andrew MA; Kovalenko M; Murtha R; Seong I; Gusella JF; Kwak S; Howland D; Lee R; Lee JM; Wheeler VC; MacDonald ME
    Hum Mol Genet; 2020 Nov; 29(18):3044-3053. PubMed ID: 32876667
    [TBL] [Abstract][Full Text] [Related]  

  • 6. FAN1, a DNA Repair Nuclease, as a Modifier of Repeat Expansion Disorders.
    Deshmukh AL; Porro A; Mohiuddin M; Lanni S; Panigrahi GB; Caron MC; Masson JY; Sartori AA; Pearson CE
    J Huntingtons Dis; 2021; 10(1):95-122. PubMed ID: 33579867
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Exome sequencing of individuals with Huntington's disease implicates FAN1 nuclease activity in slowing CAG expansion and disease onset.
    McAllister B; Donaldson J; Binda CS; Powell S; Chughtai U; Edwards G; Stone J; Lobanov S; Elliston L; Schuhmacher LN; Rees E; Menzies G; Ciosi M; Maxwell A; Chao MJ; Hong EP; Lucente D; Wheeler V; Lee JM; MacDonald ME; Long JD; Aylward EH; Landwehrmeyer GB; Rosser AE; ; Paulsen JS; ; Williams NM; Gusella JF; Monckton DG; Allen ND; Holmans P; Jones L; Massey TH
    Nat Neurosci; 2022 Apr; 25(4):446-457. PubMed ID: 35379994
    [TBL] [Abstract][Full Text] [Related]  

  • 8. FAN1's protection against CGG repeat expansion requires its nuclease activity and is FANCD2-independent.
    Zhao X; Lu H; Usdin K
    Nucleic Acids Res; 2021 Nov; 49(20):11643-11652. PubMed ID: 34718701
    [TBL] [Abstract][Full Text] [Related]  

  • 9. FAN1-MLH1 interaction affects repair of DNA interstrand cross-links and slipped-CAG/CTG repeats.
    Porro A; Mohiuddin M; Zurfluh C; Spegg V; Dai J; Iehl F; Ropars V; Collotta G; Fishwick KM; Mozaffari NL; Guérois R; Jiricny J; Altmeyer M; Charbonnier JB; Pearson CE; Sartori AA
    Sci Adv; 2021 Jul; 7(31):. PubMed ID: 34330701
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Extrahelical (CAG)/(CTG) triplet repeat elements support proliferating cell nuclear antigen loading and MutLα endonuclease activation.
    Pluciennik A; Burdett V; Baitinger C; Iyer RR; Shi K; Modrich P
    Proc Natl Acad Sci U S A; 2013 Jul; 110(30):12277-82. PubMed ID: 23840062
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Genetic and Functional Analyses Point to FAN1 as the Source of Multiple Huntington Disease Modifier Effects.
    Kim KH; Hong EP; Shin JW; Chao MJ; Loupe J; Gillis T; Mysore JS; Holmans P; Jones L; Orth M; Monckton DG; Long JD; Kwak S; Lee R; Gusella JF; MacDonald ME; Lee JM
    Am J Hum Genet; 2020 Jul; 107(1):96-110. PubMed ID: 32589923
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structural and molecular basis of FAN1 defects in promoting Huntington's disease.
    Li F; Phadte A; Bhatia M; Barndt S; Monte Carlo AR; Hou CD; Yang R; Strock S; Pluciennik A
    bioRxiv; 2024 Oct; ():. PubMed ID: 39416186
    [TBL] [Abstract][Full Text] [Related]  

  • 13. FAN1 protects against repeat expansions in a Fragile X mouse model.
    Zhao XN; Usdin K
    DNA Repair (Amst); 2018 Sep; 69():1-5. PubMed ID: 29990673
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Posttranscriptional regulation of
    Kim KH; Hong EP; Lee Y; McLean ZL; Elezi E; Lee R; Kwak S; McAllister B; Massey TH; Lobanov S; Holmans P; Orth M; Ciosi M; Monckton DG; Long JD; Lucente D; Wheeler VC; MacDonald ME; Gusella JF; Lee JM
    Proc Natl Acad Sci U S A; 2024 Apr; 121(16):e2322924121. PubMed ID: 38607933
    [TBL] [Abstract][Full Text] [Related]  

  • 15. SPYing on triplet repeat expansions: Insights into FAN1-MLH1 interaction and regulation.
    Lahue RS
    Cell Rep; 2021 Sep; 36(11):109736. PubMed ID: 34525375
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Proliferating cell nuclear antigen prevents trinucleotide repeat expansions by promoting repeat deletion and hairpin removal.
    Beaver JM; Lai Y; Rolle SJ; Liu Y
    DNA Repair (Amst); 2016 Dec; 48():17-29. PubMed ID: 27793507
    [TBL] [Abstract][Full Text] [Related]  

  • 17. MLH1-mediated recruitment of FAN1 to chromatin for the induction of apoptosis triggered by O
    Rikitake M; Fujikane R; Obayashi Y; Oka K; Ozaki M; Hidaka M
    Genes Cells; 2020 Mar; 25(3):175-186. PubMed ID: 31955481
    [TBL] [Abstract][Full Text] [Related]  

  • 18. FAN1 nuclease helps to delay Huntington disease.
    Wood H
    Nat Rev Neurol; 2022 Jun; 18(6):317. PubMed ID: 35534552
    [No Abstract]   [Full Text] [Related]  

  • 19. PCNA function in the activation and strand direction of MutLα endonuclease in mismatch repair.
    Pluciennik A; Dzantiev L; Iyer RR; Constantin N; Kadyrov FA; Modrich P
    Proc Natl Acad Sci U S A; 2010 Sep; 107(37):16066-71. PubMed ID: 20713735
    [TBL] [Abstract][Full Text] [Related]  

  • 20. FAN1 interaction with ubiquitylated PCNA alleviates replication stress and preserves genomic integrity independently of BRCA2.
    Porro A; Berti M; Pizzolato J; Bologna S; Kaden S; Saxer A; Ma Y; Nagasawa K; Sartori AA; Jiricny J
    Nat Commun; 2017 Oct; 8(1):1073. PubMed ID: 29051491
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.