These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

123 related articles for article (PubMed ID: 37549852)

  • 1. Design and structural optimization of thiadiazole derivatives with potent GLS1 inhibitory activity.
    Okada T; Yamabe K; Jo M; Sakajiri Y; Shibata T; Sawada R; Yamanishi Y; Kanayama D; Mori H; Mizuguchi M; Obita T; Nabeshima Y; Koizumi K; Toyooka N
    Bioorg Med Chem Lett; 2023 Sep; 93():129438. PubMed ID: 37549852
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Discovery of a Thiadiazole-Pyridazine-Based Allosteric Glutaminase 1 Inhibitor Series That Demonstrates Oral Bioavailability and Activity in Tumor Xenograft Models.
    Finlay MRV; Anderton M; Bailey A; Boyd S; Brookfield J; Cairnduff C; Charles M; Cheasty A; Critchlow SE; Culshaw J; Ekwuru T; Hollingsworth I; Jones N; Leroux F; Littleson M; McCarron H; McKelvie J; Mooney L; Nissink JWM; Perkins D; Powell S; Quesada MJ; Raubo P; Sabin V; Smith J; Smith PD; Stark A; Ting A; Wang P; Wilson Z; Winter-Holt JJ; Wood JM; Wrigley GL; Yu G; Zhang P
    J Med Chem; 2019 Jul; 62(14):6540-6560. PubMed ID: 31199640
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Analysis of anti-tumor effect and mechanism of GLS1 inhibitor CB-839 in colorectal cancer using a stroma-abundant tumor model.
    Miyamoto R; Takigawa H; Yuge R; Shimizu D; Ariyoshi M; Otani R; Tsuboi A; Tanaka H; Yamashita K; Hiyama Y; Urabe Y; Ishikawa A; Sentani K; Oka S
    Exp Mol Pathol; 2024 Jun; 137():104896. PubMed ID: 38703552
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Simultaneous inhibition of PFKFB3 and GLS1 selectively kills KRAS-transformed pancreatic cells.
    Ozcan SC; Mutlu A; Altunok TH; Gurpinar Y; Sarioglu A; Guler S; Muchut RJ; Iglesias AA; Celikler S; Campbell PM; Yalcin A
    Biochem Biophys Res Commun; 2021 Sep; 571():118-124. PubMed ID: 34325126
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design, synthesis, structure-activity relationship studies, and evaluation of novel GLS1 inhibitors.
    Jo M; Koizumi K; Suzuki M; Kanayama D; Watanabe Y; Gouda H; Mori H; Mizuguchi M; Obita T; Nabeshima Y; Toyooka N; Okada T
    Bioorg Med Chem Lett; 2023 May; 87():129266. PubMed ID: 37011768
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design, Synthesis and Biological Evaluation of a Novel Series of Thiadiazole- Based Anticancer Agents as Potent Angiogenesis Inhibitors.
    Altuğ-Tasa B; Kaya-Çavuşoğlu B; Koparal AT; Turan G; Koparal AS; Kaplancıklı ZA
    Anticancer Agents Med Chem; 2021; 21(15):2041-2049. PubMed ID: 33390125
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Design, microwave assisted synthesis, and molecular modeling study of some new 1,3,4-thiadiazole derivatives as potent anticancer agents and potential VEGFR-2 inhibitors.
    Atta-Allah SR; AboulMagd AM; Farag PS
    Bioorg Chem; 2021 Jul; 112():104923. PubMed ID: 33932767
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Development of adamantane scaffold containing 1,3,4-thiadiazole derivatives: Design, synthesis, anti-proliferative activity and molecular docking study targeting EGFR.
    Wassel MMS; Ammar YA; Elhag Ali GAM; Belal A; Mehany ABM; Ragab A
    Bioorg Chem; 2021 May; 110():104794. PubMed ID: 33735711
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Discovery and optimization of withangulatin A derivatives as novel glutaminase 1 inhibitors for the treatment of triple-negative breast cancer.
    Zhou WX; Chen C; Liu XQ; Li Y; Lin YL; Wu XT; Kong LY; Luo JG
    Eur J Med Chem; 2021 Jan; 210():112980. PubMed ID: 33176943
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Recent Development of Small Molecule Glutaminase Inhibitors.
    Song M; Kim SH; Im CY; Hwang HJ
    Curr Top Med Chem; 2018; 18(6):432-443. PubMed ID: 29793408
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Novel diosgenin derivatives containing 1,3,4-oxadiazole/thiadiazole moieties as potential antitumor agents: Design, synthesis and cytotoxic evaluation.
    Zhang J; Wang X; Yang J; Guo L; Wang X; Song B; Dong W; Wang W
    Eur J Med Chem; 2020 Jan; 186():111897. PubMed ID: 31761382
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Glutamine metabolism via glutaminase 1 in autosomal-dominant polycystic kidney disease.
    Soomro I; Sun Y; Li Z; Diggs L; Hatzivassiliou G; Thomas AG; Rais R; Parker SJ; Slusher BS; Kimmelman AC; Somlo S; Skolnik EY
    Nephrol Dial Transplant; 2018 Aug; 33(8):1343-1353. PubMed ID: 29420817
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis, biological evaluation, and molecular docking studies of cinnamic acyl 1,3,4-thiadiazole amide derivatives as novel antitubulin agents.
    Yang XH; Wen Q; Zhao TT; Sun J; Li X; Xing M; Lu X; Zhu HL
    Bioorg Med Chem; 2012 Feb; 20(3):1181-7. PubMed ID: 22261027
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structure-Enabled Discovery of Novel Macrocyclic Inhibitors Targeting Glutaminase 1 Allosteric Binding Site.
    Xu X; Wang J; Wang M; Yuan X; Li L; Zhang C; Huang H; Jing T; Wang C; Tong C; Zhou L; Meng Y; Xu P; Kou J; Qiu Z; Li Z; Bian J
    J Med Chem; 2021 Apr; 64(8):4588-4611. PubMed ID: 33792311
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design, synthesis, and pharmacological evaluation of 2-(1-(1,3,4-thiadiazol-2-yl)piperidin-4-yl)ethan-1-ol analogs as novel glutaminase 1 inhibitors.
    Yang T; Tian Y; Yang Y; Tang M; Shi M; Chen Y; Yang Z; Chen L
    Eur J Med Chem; 2022 Dec; 243():114686. PubMed ID: 36055003
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Discovery of novel glutaminase 1 allosteric inhibitor with 4-piperidinamine linker and aromatic heterocycles.
    Xu X; Chang X; Huang J; Zhang D; Wang M; Jing T; Zhuang Y; Kou J; Qiu Z; Wang J; Li Z; Bian J
    Eur J Med Chem; 2022 Jun; 236():114337. PubMed ID: 35428013
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Exploring indole-based-thiadiazole derivatives as potent acetylcholinesterase and butyrylcholinesterase enzyme inhibitors.
    Taha M; Rahim F; Uddin N; Khan IU; Iqbal N; Anouar EH; Salahuddin M; Farooq RK; Gollapalli M; Khan KM; Zafar A
    Int J Biol Macromol; 2021 Oct; 188():1025-1036. PubMed ID: 34390751
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis, Molecular Docking Screening and Anti-Proliferative Potency Evaluation of Some New Imidazo[2,1-
    Rashdan HRM; Abdelmonsef AH; Shehadi IA; Gomha SM; Soliman AMM; Mahmoud HK
    Molecules; 2020 Oct; 25(21):. PubMed ID: 33126630
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Targeting glutaminolysis has antileukemic activity in acute myeloid leukemia and synergizes with BCL-2 inhibition.
    Jacque N; Ronchetti AM; Larrue C; Meunier G; Birsen R; Willems L; Saland E; Decroocq J; Maciel TT; Lambert M; Poulain L; Hospital MA; Sujobert P; Joseph L; Chapuis N; Lacombe C; Moura IC; Demo S; Sarry JE; Recher C; Mayeux P; Tamburini J; Bouscary D
    Blood; 2015 Sep; 126(11):1346-56. PubMed ID: 26186940
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 5-(Thiophen-2-yl)-1,3,4-thiadiazole derivatives: synthesis, molecular docking and in vitro cytotoxicity evaluation as potential anticancer agents.
    Gomha SM; Edrees MM; Muhammad ZA; El-Reedy AA
    Drug Des Devel Ther; 2018; 12():1511-1523. PubMed ID: 29881258
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.