BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

252 related articles for article (PubMed ID: 37560909)

  • 21. G-quadruplex formation in telomeres enhances POT1/TPP1 protection against RPA binding.
    Ray S; Bandaria JN; Qureshi MH; Yildiz A; Balci H
    Proc Natl Acad Sci U S A; 2014 Feb; 111(8):2990-5. PubMed ID: 24516170
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Human POT1 protects the telomeric ds-ss DNA junction by capping the 5' end of the chromosome.
    Tesmer VM; Brenner KA; Nandakumar J
    Science; 2023 Aug; 381(6659):771-778. PubMed ID: 37590346
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Pot1b deletion and telomerase haploinsufficiency in mice initiate an ATR-dependent DNA damage response and elicit phenotypes resembling dyskeratosis congenita.
    He H; Wang Y; Guo X; Ramchandani S; Ma J; Shen MF; Garcia DA; Deng Y; Multani AS; You MJ; Chang S
    Mol Cell Biol; 2009 Jan; 29(1):229-40. PubMed ID: 18936156
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Distinct functions of POT1 at telomeres.
    Barrientos KS; Kendellen MF; Freibaum BD; Armbruster BN; Etheridge KT; Counter CM
    Mol Cell Biol; 2008 Sep; 28(17):5251-64. PubMed ID: 18519588
    [TBL] [Abstract][Full Text] [Related]  

  • 25. RPA prevents G-rich structure formation at lagging-strand telomeres to allow maintenance of chromosome ends.
    Audry J; Maestroni L; Delagoutte E; Gauthier T; Nakamura TM; Gachet Y; Saintomé C; Géli V; Coulon S
    EMBO J; 2015 Jul; 34(14):1942-58. PubMed ID: 26041456
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1.
    Denchi EL; de Lange T
    Nature; 2007 Aug; 448(7157):1068-71. PubMed ID: 17687332
    [TBL] [Abstract][Full Text] [Related]  

  • 27. TPP1 is a homologue of ciliate TEBP-beta and interacts with POT1 to recruit telomerase.
    Xin H; Liu D; Wan M; Safari A; Kim H; Sun W; O'Connor MS; Songyang Z
    Nature; 2007 Feb; 445(7127):559-62. PubMed ID: 17237767
    [TBL] [Abstract][Full Text] [Related]  

  • 28. A mouse model for Li-Fraumeni-Like Syndrome with cardiac angiosarcomas associated to POT1 mutations.
    Martínez P; Sánchez-Vázquez R; Ferrara-Romeo I; Serrano R; Flores JM; Blasco MA
    PLoS Genet; 2022 Jun; 18(6):e1010260. PubMed ID: 35727838
    [TBL] [Abstract][Full Text] [Related]  

  • 29. A POT1 mutation implicates defective telomere end fill-in and telomere truncations in Coats plus.
    Takai H; Jenkinson E; Kabir S; Babul-Hirji R; Najm-Tehrani N; Chitayat DA; Crow YJ; de Lange T
    Genes Dev; 2016 Apr; 30(7):812-26. PubMed ID: 27013236
    [TBL] [Abstract][Full Text] [Related]  

  • 30. In vivo stoichiometry of shelterin components.
    Takai KK; Hooper S; Blackwood S; Gandhi R; de Lange T
    J Biol Chem; 2010 Jan; 285(2):1457-67. PubMed ID: 19864690
    [TBL] [Abstract][Full Text] [Related]  

  • 31. POT1-TPP1 Binding and Unfolding of Telomere DNA Discriminates against Structural Polymorphism.
    Mullins MR; Rajavel M; Hernandez-Sanchez W; de la Fuente M; Biendarra SM; Harris ME; Taylor DJ
    J Mol Biol; 2016 Jul; 428(13):2695-708. PubMed ID: 27173378
    [TBL] [Abstract][Full Text] [Related]  

  • 32. A novel small molecule that alters shelterin integrity and triggers a DNA-damage response at telomeres.
    Rodriguez R; Müller S; Yeoman JA; Trentesaux C; Riou JF; Balasubramanian S
    J Am Chem Soc; 2008 Nov; 130(47):15758-9. PubMed ID: 18975896
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Dissecting Fission Yeast Shelterin Interactions via MICro-MS Links Disruption of Shelterin Bridge to Tumorigenesis.
    Liu J; Yu C; Hu X; Kim JK; Bierma JC; Jun HI; Rychnovsky SD; Huang L; Qiao F
    Cell Rep; 2015 Sep; 12(12):2169-80. PubMed ID: 26365187
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Cancer-associated POT1 mutations lead to telomere elongation without induction of a DNA damage response.
    Kim WT; Hennick K; Johnson J; Finnerty B; Choo S; Short SB; Drubin C; Forster R; McMaster ML; Hockemeyer D
    EMBO J; 2021 Jun; 40(12):e107346. PubMed ID: 33934394
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Human POT1 disrupts telomeric G-quadruplexes allowing telomerase extension in vitro.
    Zaug AJ; Podell ER; Cech TR
    Proc Natl Acad Sci U S A; 2005 Aug; 102(31):10864-9. PubMed ID: 16043710
    [TBL] [Abstract][Full Text] [Related]  

  • 36. G-quadruplex-mediated regulation of telomere binding protein POT1 gene expression.
    He Q; Zeng P; Tan JH; Ou TM; Gu LQ; Huang ZS; Li D
    Biochim Biophys Acta; 2014 Jul; 1840(7):2222-33. PubMed ID: 24631651
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Human protection of telomeres 1 (POT1) is a negative regulator of telomerase activity in vitro.
    Kelleher C; Kurth I; Lingner J
    Mol Cell Biol; 2005 Jan; 25(2):808-18. PubMed ID: 15632080
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Single-Molecule Imaging of Telomerase RNA Reveals a Recruitment-Retention Model for Telomere Elongation.
    Laprade H; Querido E; Smith MJ; Guérit D; Crimmins H; Conomos D; Pourret E; Chartrand P; Sfeir A
    Mol Cell; 2020 Jul; 79(1):115-126.e6. PubMed ID: 32497497
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Replication stress conferred by POT1 dysfunction promotes telomere relocalization to the nuclear pore.
    Pinzaru AM; Kareh M; Lamm N; Lazzerini-Denchi E; Cesare AJ; Sfeir A
    Genes Dev; 2020 Dec; 34(23-24):1619-1636. PubMed ID: 33122293
    [TBL] [Abstract][Full Text] [Related]  

  • 40. TRF1 negotiates TTAGGG repeat-associated replication problems by recruiting the BLM helicase and the TPP1/POT1 repressor of ATR signaling.
    Zimmermann M; Kibe T; Kabir S; de Lange T
    Genes Dev; 2014 Nov; 28(22):2477-91. PubMed ID: 25344324
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 13.