BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

137 related articles for article (PubMed ID: 37562955)

  • 1. The Utility of Mixed Effects Models in the Evaluation of Complex Genomic Traits In Vitro.
    Alade N; Nath A; Isoherranen N; Thummel KE
    Drug Metab Dispos; 2023 Nov; 51(11):1455-1462. PubMed ID: 37562955
    [TBL] [Abstract][Full Text] [Related]  

  • 2. In vitro metabolism of the calmodulin antagonist DY-9760e (3-[2-[4-(3-chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole dihydrochloride 3.5 hydrate) by human liver microsomes: involvement of cytochromes p450 in atypical kinetics and potential drug interactions.
    Tachibana S; Fujimaki Y; Yokoyama H; Okazaki O; Sudo K
    Drug Metab Dispos; 2005 Nov; 33(11):1628-36. PubMed ID: 16049129
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Hydroxychloroquine is Metabolized by Cytochrome P450 2D6, 3A4, and 2C8, and Inhibits Cytochrome P450 2D6, while its Metabolites also Inhibit Cytochrome P450 3A
    Paludetto MN; Kurkela M; Kahma H; Backman JT; Niemi M; Filppula AM
    Drug Metab Dispos; 2023 Mar; 51(3):293-305. PubMed ID: 36446607
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Halofantrine metabolism in microsomes in man: major role of CYP 3A4 and CYP 3A5.
    Baune B; Flinois JP; Furlan V; Gimenez F; Taburet AM; Becquemont L; Farinotti R
    J Pharm Pharmacol; 1999 Apr; 51(4):419-26. PubMed ID: 10385214
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Approach to predict the contribution of cytochrome P450 enzymes to drug metabolism in the early drug-discovery stage: the effect of the expression of cytochrome b(5) with recombinant P450 enzymes.
    Emoto C; Iwasaki K
    Xenobiotica; 2007 Sep; 37(9):986-99. PubMed ID: 17896325
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Strategies for Determining Correct Cytochrome P450 Contributions in Hepatic Clearance Predictions: In Vitro-In Vivo Extrapolation as Modelling Approach and Tramadol as Proof-of Concept Compound.
    T'jollyn H; Snoeys J; Van Bocxlaer J; De Bock L; Annaert P; Van Peer A; Allegaert K; Mannens G; Vermeulen A; Boussery K
    Eur J Drug Metab Pharmacokinet; 2017 Jun; 42(3):537-543. PubMed ID: 27317395
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Metabolism of dextromethorphan in vitro: involvement of cytochromes P450 2D6 and 3A3/4, with a possible role of 2E1.
    Schmider J; Greenblatt DJ; Fogelman SM; von Moltke LL; Shader RI
    Biopharm Drug Dispos; 1997 Apr; 18(3):227-40. PubMed ID: 9113345
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition kinetics of monoclonal antibodies against cytochromes P450.
    Mei Q; Tang C; Lin Y; Rushmore TH; Shou M
    Drug Metab Dispos; 2002 Jun; 30(6):701-8. PubMed ID: 12019198
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification of cytochrome P450 isoforms involved in the metabolism of paroxetine and estimation of their importance for human paroxetine metabolism using a population-based simulator.
    Jornil J; Jensen KG; Larsen F; Linnet K
    Drug Metab Dispos; 2010 Mar; 38(3):376-85. PubMed ID: 20007670
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Azelastine N-demethylation by cytochrome P-450 (CYP)3A4, CYP2D6, and CYP1A2 in human liver microsomes: evaluation of approach to predict the contribution of multiple CYPs.
    Nakajima M; Nakamura S; Tokudome S; Shimada N; Yamazaki H; Yokoi T
    Drug Metab Dispos; 1999 Dec; 27(12):1381-91. PubMed ID: 10570018
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Nortriptyline E-10-hydroxylation in vitro is mediated by human CYP2D6 (high affinity) and CYP3A4 (low affinity): implications for interactions with enzyme-inducing drugs.
    Venkatakrishnan K; von Moltke LL; Greenblatt DJ
    J Clin Pharmacol; 1999 Jun; 39(6):567-77. PubMed ID: 10354960
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Identification of three cytochrome P450 isozymes involved in N-demethylation of citalopram enantiomers in human liver microsomes.
    Rochat B; Amey M; Gillet M; Meyer UA; Baumann P
    Pharmacogenetics; 1997 Feb; 7(1):1-10. PubMed ID: 9110356
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Bufuralol hydroxylation by cytochrome P450 2D6 and 1A2 enzymes in human liver microsomes.
    Yamazaki H; Guo Z; Persmark M; Mimura M; Inoue K; Guengerich FP; Shimada T
    Mol Pharmacol; 1994 Sep; 46(3):568-77. PubMed ID: 7935340
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification of human liver cytochrome P450 isoforms involved in the in vitro metabolism of cyclobenzaprine.
    Wang RW; Liu L; Cheng H
    Drug Metab Dispos; 1996 Jul; 24(7):786-91. PubMed ID: 8818577
    [TBL] [Abstract][Full Text] [Related]  

  • 15. O- and N-demethylation of venlafaxine in vitro by human liver microsomes and by microsomes from cDNA-transfected cells: effect of metabolic inhibitors and SSRI antidepressants.
    Fogelman SM; Schmider J; Venkatakrishnan K; von Moltke LL; Harmatz JS; Shader RI; Greenblatt DJ
    Neuropsychopharmacology; 1999 May; 20(5):480-90. PubMed ID: 10192828
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Evaluation of Supermix as an in vitro model of human liver microsomal drug metabolism.
    Venkatakrishnan K; Von Moltke LL; Greenblatt DJ
    Biopharm Drug Dispos; 2002 Jul; 23(5):183-90. PubMed ID: 12116049
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Optimizing higher throughput methods to assess drug-drug interactions for CYP1A2, CYP2C9, CYP2C19, CYP2D6, rCYP2D6, and CYP3A4 in vitro using a single point IC(50).
    Gao F; Johnson DL; Ekins S; Janiszewski J; Kelly KG; Meyer RD; West M
    J Biomol Screen; 2002 Aug; 7(4):373-82. PubMed ID: 12230892
    [TBL] [Abstract][Full Text] [Related]  

  • 18. In vitro inhibition of human cytochrome P450 enzymes by the novel atypical antipsychotic drug asenapine: a prediction of possible drug-drug interactions.
    Wójcikowski J; Danek PJ; Basińska-Ziobroń A; Pukło R; Daniel WA
    Pharmacol Rep; 2020 Jun; 72(3):612-621. PubMed ID: 32219694
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Potential interactions of methylphenidate and atomoxetine with dextromethorphan.
    Ciccone PE; Ramabadran K; Jessen LM
    J Am Pharm Assoc (2003); 2006; 46(4):472-8. PubMed ID: 16913391
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Interindividual variability in catalytic activity and immunoreactivity of three major human liver cytochrome P450 isozymes.
    Transon C; Lecoeur S; Leemann T; Beaune P; Dayer P
    Eur J Clin Pharmacol; 1996; 51(1):79-85. PubMed ID: 8880056
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.