These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

119 related articles for article (PubMed ID: 37567474)

  • 1. Biochemical functions and structure of Caenorhabditis elegans ZK177.8 protein: Aicardi-Goutières syndrome SAMHD1 dNTPase ortholog.
    Maehigashi T; Lim C; Wade LR; Bowen NE; Knecht KM; Alvarez NN; Kelly WG; Schinazi RF; Kim DH; Xiong Y; Kim B
    J Biol Chem; 2023 Sep; 299(9):105148. PubMed ID: 37567474
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structural basis of cellular dNTP regulation by SAMHD1.
    Ji X; Tang C; Zhao Q; Wang W; Xiong Y
    Proc Natl Acad Sci U S A; 2014 Oct; 111(41):E4305-14. PubMed ID: 25267621
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Impaired dNTPase activity of SAMHD1 by phosphomimetic mutation of Thr-592.
    Tang C; Ji X; Wu L; Xiong Y
    J Biol Chem; 2015 Oct; 290(44):26352-9. PubMed ID: 26294762
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural and functional characterization explains loss of dNTPase activity of the cancer-specific R366C/H mutant SAMHD1 proteins.
    Bowen NE; Temple J; Shepard C; Oo A; Arizaga F; Kapoor-Vazirani P; Persaud M; Yu CH; Kim DH; Schinazi RF; Ivanov DN; Diaz-Griffero F; Yu DS; Xiong Y; Kim B
    J Biol Chem; 2021 Oct; 297(4):101170. PubMed ID: 34492268
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structural Insights into the High-efficiency Catalytic Mechanism of the Sterile α-Motif/Histidine-Aspartate Domain-containing Protein.
    Li Y; Kong J; Peng X; Hou W; Qin X; Yu XF
    J Biol Chem; 2015 Dec; 290(49):29428-37. PubMed ID: 26438820
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A Cyclin-Binding Motif in Human SAMHD1 Is Required for Its HIV-1 Restriction, dNTPase Activity, Tetramer Formation, and Efficient Phosphorylation.
    St Gelais C; Kim SH; Maksimova VV; Buzovetsky O; Knecht KM; Shepard C; Kim B; Xiong Y; Wu L
    J Virol; 2018 Mar; 92(6):. PubMed ID: 29321329
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural insight into dGTP-dependent activation of tetrameric SAMHD1 deoxynucleoside triphosphate triphosphohydrolase.
    Zhu C; Gao W; Zhao K; Qin X; Zhang Y; Peng X; Zhang L; Dong Y; Zhang W; Li P; Wei W; Gong Y; Yu XF
    Nat Commun; 2013; 4():2722. PubMed ID: 24217394
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mechanism of allosteric activation of SAMHD1 by dGTP.
    Ji X; Wu Y; Yan J; Mehrens J; Yang H; DeLucia M; Hao C; Gronenborn AM; Skowronski J; Ahn J; Xiong Y
    Nat Struct Mol Biol; 2013 Nov; 20(11):1304-9. PubMed ID: 24141705
    [TBL] [Abstract][Full Text] [Related]  

  • 9. SAMHD1 Functions and Human Diseases.
    Coggins SA; Mahboubi B; Schinazi RF; Kim B
    Viruses; 2020 Mar; 12(4):. PubMed ID: 32244340
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Allosteric regulation of the human and mouse deoxyribonucleotide triphosphohydrolase sterile α-motif/histidine-aspartate domain-containing protein 1 (SAMHD1).
    Miazzi C; Ferraro P; Pontarin G; Rampazzo C; Reichard P; Bianchi V
    J Biol Chem; 2014 Jun; 289(26):18339-46. PubMed ID: 24828500
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The missing link: allostery and catalysis in the anti-viral protein SAMHD1.
    Morris ER; Taylor IA
    Biochem Soc Trans; 2019 Aug; 47(4):1013-1027. PubMed ID: 31296733
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The mechanism of substrate-controlled allosteric regulation of SAMHD1 activated by GTP.
    Zhu CF; Wei W; Peng X; Dong YH; Gong Y; Yu XF
    Acta Crystallogr D Biol Crystallogr; 2015 Mar; 71(Pt 3):516-24. PubMed ID: 25760601
    [TBL] [Abstract][Full Text] [Related]  

  • 13. HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase.
    Goldstone DC; Ennis-Adeniran V; Hedden JJ; Groom HC; Rice GI; Christodoulou E; Walker PA; Kelly G; Haire LF; Yap MW; de Carvalho LP; Stoye JP; Crow YJ; Taylor IA; Webb M
    Nature; 2011 Nov; 480(7377):379-82. PubMed ID: 22056990
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structural basis of allosteric activation of sterile α motif and histidine-aspartate domain-containing protein 1 (SAMHD1) by nucleoside triphosphates.
    Koharudin LM; Wu Y; DeLucia M; Mehrens J; Gronenborn AM; Ahn J
    J Biol Chem; 2014 Nov; 289(47):32617-27. PubMed ID: 25288794
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Dual roles of SAMHD1 in tumor development and chemoresistance to anticancer drugs.
    Chen Z; Hu J; Ying S; Xu A
    Oncol Lett; 2021 Jun; 21(6):451. PubMed ID: 33907561
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Crystal structures of SAMHD1 inhibitor complexes reveal the mechanism of water-mediated dNTP hydrolysis.
    Morris ER; Caswell SJ; Kunzelmann S; Arnold LH; Purkiss AG; Kelly G; Taylor IA
    Nat Commun; 2020 Jun; 11(1):3165. PubMed ID: 32576829
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Probing the Catalytic Mechanism and Inhibition of SAMHD1 Using the Differential Properties of R
    Morris ER; Kunzelmann S; Caswell SJ; Purkiss AG; Kelly G; Taylor IA
    Biochemistry; 2021 Jun; 60(21):1682-1698. PubMed ID: 33988981
    [TBL] [Abstract][Full Text] [Related]  

  • 18. CyclinA2-Cyclin-dependent Kinase Regulates SAMHD1 Protein Phosphohydrolase Domain.
    Yan J; Hao C; DeLucia M; Swanson S; Florens L; Washburn MP; Ahn J; Skowronski J
    J Biol Chem; 2015 May; 290(21):13279-92. PubMed ID: 25847232
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structural characterization and directed modification of Sus scrofa SAMHD1 reveal the mechanism underlying deoxynucleotide regulation.
    Kong J; Wang MM; He SY; Peng X; Qin XH
    FEBS J; 2019 Oct; 286(19):3844-3857. PubMed ID: 31152619
    [TBL] [Abstract][Full Text] [Related]  

  • 20. SAMHD1: Recurring roles in cell cycle, viral restriction, cancer, and innate immunity.
    Mauney CH; Hollis T
    Autoimmunity; 2018 May; 51(3):96-110. PubMed ID: 29583030
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.