These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

128 related articles for article (PubMed ID: 37572851)

  • 1. Quantitative proteomics and phosphoproteomics of PP2A-PPP2R5D variants reveal deregulation of RPS6 phosphorylation via converging signaling cascades.
    Smolen KA; Papke CM; Swingle MR; Musiyenko A; Li C; Salter EA; Camp AD; Honkanen RE; Kettenbach AN
    J Biol Chem; 2023 Sep; 299(9):105154. PubMed ID: 37572851
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Quantitative proteomics and phosphoproteomics of PPP2R5D variants reveal deregulation of RPS6 phosphorylation through converging signaling cascades.
    Ka S; Cm P; Swingle MR; A M; C L; Ad C; Re H; An K
    bioRxiv; 2023 Mar; ():. PubMed ID: 37034727
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A disorder-related variant (E420K) of a PP2A-regulatory subunit (PPP2R5D) causes constitutively active AKT-mTOR signaling and uncoordinated cell growth.
    Papke CM; Smolen KA; Swingle MR; Cressey L; Heng RA; Toporsian M; Deng L; Hagen J; Shen Y; Chung WK; Kettenbach AN; Honkanen RE
    J Biol Chem; 2021; 296():100313. PubMed ID: 33482199
    [TBL] [Abstract][Full Text] [Related]  

  • 4. PPP2R5D-Related Intellectual Disability and Neurodevelopmental Delay: A Review of the Current Understanding of the Genetics and Biochemical Basis of the Disorder.
    Biswas D; Cary W; Nolta JA
    Int J Mol Sci; 2020 Feb; 21(4):. PubMed ID: 32074998
    [TBL] [Abstract][Full Text] [Related]  

  • 5. De novo missense variants in PPP2R5D are associated with intellectual disability, macrocephaly, hypotonia, and autism.
    Shang L; Henderson LB; Cho MT; Petrey DS; Fong CT; Haude KM; Shur N; Lundberg J; Hauser N; Carmichael J; Innis J; Schuette J; Wu YW; Asaikar S; Pearson M; Folk L; Retterer K; Monaghan KG; Chung WK
    Neurogenetics; 2016 Jan; 17(1):43-9. PubMed ID: 26576547
    [TBL] [Abstract][Full Text] [Related]  

  • 6. DRAM1 regulates autophagy and cell proliferation via inhibition of the phosphoinositide 3-kinase-Akt-mTOR-ribosomal protein S6 pathway.
    Lu T; Zhu Z; Wu J; She H; Han R; Xu H; Qin ZH
    Cell Commun Signal; 2019 Mar; 17(1):28. PubMed ID: 30902093
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Resistance to Selumetinib (AZD6244) in colorectal cancer cell lines is mediated by p70S6K and RPS6 activation.
    Grasso S; Tristante E; Saceda M; Carbonell P; Mayor-López L; Carballo-Santana M; Carrasco-García E; Rocamora-Reverte L; García-Morales P; Carballo F; Ferragut JA; Martínez-Lacaci I
    Neoplasia; 2014 Oct; 16(10):845-60. PubMed ID: 25379021
    [TBL] [Abstract][Full Text] [Related]  

  • 8. A Novel Missense Variant in the Gene
    Yan L; Shen R; Cao Z; Han C; Zhang Y; Liu Y; Yang X; Xie M; Li H
    Biomed Res Int; 2021; 2021():6661860. PubMed ID: 33628804
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Quantum-based modeling implies that bidentate Arg
    Salter EA; Wierzbicki A; Honkanen RE; Swingle MR
    Front Cell Dev Biol; 2023; 11():1141804. PubMed ID: 37377738
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Clinical, neuroimaging and molecular characteristics of
    Oyama N; Vaneynde P; Reynhout S; Pao EM; Timms A; Fan X; Foss K; Derua R; Janssens V; Chung W; Mirzaa GM
    J Med Genet; 2023 May; 60(5):511-522. PubMed ID: 36216457
    [TBL] [Abstract][Full Text] [Related]  

  • 11. DRD3 (dopamine receptor D3) but not DRD2 activates autophagy through MTORC1 inhibition preserving protein synthesis.
    Barroso-Chinea P; Luis-Ravelo D; Fumagallo-Reading F; Castro-Hernandez J; Salas-Hernandez J; Rodriguez-Nuñez J; Febles-Casquero A; Cruz-Muros I; Afonso-Oramas D; Abreu-Gonzalez P; Moratalla R; Millan MJ; Gonzalez-Hernandez T
    Autophagy; 2020 Jul; 16(7):1279-1295. PubMed ID: 31538542
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Clinical features of PPP2 syndrome type R5D (Jordan's syndrome) to support standardization of care.
    Levine AD; Chung WK
    Cold Spring Harb Mol Case Stud; 2023 Jun; 9(3):. PubMed ID: 37339871
    [TBL] [Abstract][Full Text] [Related]  

  • 13. PP2A inhibitor SET promotes mTORC1 and Bmi1 signaling through Akt activation and maintains the colony-formation ability of cancer cells.
    Kohyanagi N; Kitamura N; Ikeda S; Shibutani S; Sato K; Ohama T
    J Biol Chem; 2024 Jan; 300(1):105584. PubMed ID: 38141761
    [TBL] [Abstract][Full Text] [Related]  

  • 14. B56δ long-disordered arms form a dynamic PP2A regulation interface coupled with global allostery and Jordan's syndrome mutations.
    Wu CG; Balakrishnan VK; Merrill RA; Parihar PS; Konovolov K; Chen YC; Xu Z; Wei H; Sundaresan R; Cui Q; Wadzinski BE; Swingle MR; Musiyenko A; Chung WK; Honkanen RE; Suzuki A; Huang X; Strack S; Xing Y
    Proc Natl Acad Sci U S A; 2024 Jan; 121(1):e2310727120. PubMed ID: 38150499
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mammalian target of rapamycin complex 1 (mTORC1) plays a role in Pasteurella multocida toxin (PMT)-induced protein synthesis and proliferation in Swiss 3T3 cells.
    Oubrahim H; Wong A; Wilson BA; Chock PB
    J Biol Chem; 2013 Jan; 288(4):2805-15. PubMed ID: 23223576
    [TBL] [Abstract][Full Text] [Related]  

  • 16. An in-frame deletion affecting the critical acid loop of PPP2R5D is associated with a neonatal lethal form of PPP2R5D-related neurodevelopmental disorder.
    Alhajaj G; Lacroix C; Trakadis Y; Garfinkle J; Srour M
    Am J Med Genet A; 2023 Sep; 191(9):2416-2421. PubMed ID: 37248744
    [TBL] [Abstract][Full Text] [Related]  

  • 17. 4EBP1/eIF4E and p70S6K/RPS6 axes play critical and distinct roles in hepatocarcinogenesis driven by AKT and N-Ras proto-oncogenes in mice.
    Wang C; Cigliano A; Jiang L; Li X; Fan B; Pilo MG; Liu Y; Gui B; Sini M; Smith JW; Dombrowski F; Calvisi DF; Evert M; Chen X
    Hepatology; 2015 Jan; 61(1):200-13. PubMed ID: 25145583
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Thirteen New Patients of
    Jiang Y; Wu B; Zhang X; Yang L; Wang S; Li H; Zhou S; Qian Y; Wang H
    Children (Basel); 2024 Jul; 11(8):. PubMed ID: 39201832
    [TBL] [Abstract][Full Text] [Related]  

  • 19. RAS/ERK signaling promotes site-specific ribosomal protein S6 phosphorylation via RSK and stimulates cap-dependent translation.
    Roux PP; Shahbazian D; Vu H; Holz MK; Cohen MS; Taunton J; Sonenberg N; Blenis J
    J Biol Chem; 2007 May; 282(19):14056-64. PubMed ID: 17360704
    [TBL] [Abstract][Full Text] [Related]  

  • 20.
    ; ; . PubMed ID:
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 7.