BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

221 related articles for article (PubMed ID: 37582658)

  • 1. Pre-rRNA Facilitates TopBP1-Mediated DNA Double-Strand Break Response.
    Xin D; Gai X; Ma Y; Li Z; Li Q; Yu X
    Adv Sci (Weinh); 2023 Oct; 10(28):e2206931. PubMed ID: 37582658
    [TBL] [Abstract][Full Text] [Related]  

  • 2. MRN-dependent and independent pathways for recruitment of TOPBP1 to DNA double-strand breaks.
    Montales K; Ruis K; Lindsay H; Michael WM
    PLoS One; 2022; 17(8):e0271905. PubMed ID: 35917319
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Treacle controls the nucleolar response to rDNA breaks via TOPBP1 recruitment and ATR activation.
    Mooser C; Symeonidou IE; Leimbacher PA; Ribeiro A; Shorrocks AK; Jungmichel S; Larsen SC; Knechtle K; Jasrotia A; Zurbriggen D; Jeanrenaud A; Leikauf C; Fink D; Nielsen ML; Blackford AN; Stucki M
    Nat Commun; 2020 Jan; 11(1):123. PubMed ID: 31913317
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Delineation of a minimal topoisomerase II binding protein 1 for regulated activation of ATR at DNA double-strand breaks.
    Ruis K; Huynh O; Montales K; Barr NA; Michael WM
    J Biol Chem; 2022 Jul; 298(7):101992. PubMed ID: 35490781
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Interaction between Rad9-Hus1-Rad1 and TopBP1 activates ATR-ATRIP and promotes TopBP1 recruitment to sites of UV-damage.
    Ohashi E; Takeishi Y; Ueda S; Tsurimoto T
    DNA Repair (Amst); 2014 Sep; 21():1-11. PubMed ID: 25091155
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pre-ribosomal RNA reorganizes DNA damage repair factors in nucleus during meiotic prophase and DNA damage response.
    Gai X; Xin D; Wu D; Wang X; Chen L; Wang Y; Ma K; Li Q; Li P; Yu X
    Cell Res; 2022 Mar; 32(3):254-268. PubMed ID: 34980897
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Double-strand breaks in ribosomal RNA genes activate a distinct signaling and chromatin response to facilitate nucleolar restructuring and repair.
    Korsholm LM; Gál Z; Lin L; Quevedo O; Ahmad DA; Dulina E; Luo Y; Bartek J; Larsen DH
    Nucleic Acids Res; 2019 Sep; 47(15):8019-8035. PubMed ID: 31184714
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Phosphorylation of the BRCA1 C terminus (BRCT) repeat inhibitor of hTERT (BRIT1) protein coordinates TopBP1 protein recruitment and amplifies ataxia telangiectasia-mutated and Rad3-related (ATR) Signaling.
    Zhang B; Wang E; Dai H; Shen J; Hsieh HJ; Lu X; Peng G
    J Biol Chem; 2014 Dec; 289(49):34284-95. PubMed ID: 25301947
    [TBL] [Abstract][Full Text] [Related]  

  • 9. CtIP- and ATR-dependent FANCJ phosphorylation in response to DNA strand breaks mediated by DNA replication.
    Sakasai R; Sakai A; Iimori M; Kiyonari S; Matsuoka K; Kakeji Y; Kitao H; Maehara Y
    Genes Cells; 2012 Dec; 17(12):962-70. PubMed ID: 23157317
    [TBL] [Abstract][Full Text] [Related]  

  • 10. CtIP interacts with TopBP1 and Nbs1 in the response to double-stranded DNA breaks (DSBs) in Xenopus egg extracts.
    Ramírez-Lugo JS; Yoo HY; Yoon SJ; Dunphy WG
    Cell Cycle; 2011 Feb; 10(3):469-80. PubMed ID: 21263215
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Overexpression of TopBP1, a canonical ATR/Chk1 activator, paradoxically hinders ATR/Chk1 activation in cancer.
    Liu K; Graves JD; Lin FT; Lin WC
    J Biol Chem; 2021; 296():100382. PubMed ID: 33556369
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Two distinct modes of ATR activation orchestrated by Rad17 and Nbs1.
    Shiotani B; Nguyen HD; Håkansson P; Maréchal A; Tse A; Tahara H; Zou L
    Cell Rep; 2013 May; 3(5):1651-62. PubMed ID: 23684611
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Localization of Double-Strand Break Repair Proteins to Viral Replication Compartments following Lytic Reactivation of Kaposi's Sarcoma-Associated Herpesvirus.
    Hollingworth R; Horniblow RD; Forrest C; Stewart GS; Grand RJ
    J Virol; 2017 Nov; 91(22):. PubMed ID: 28855246
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ataxia-telangiectasia mutated (ATM)-dependent activation of ATR occurs through phosphorylation of TopBP1 by ATM.
    Yoo HY; Kumagai A; Shevchenko A; Shevchenko A; Dunphy WG
    J Biol Chem; 2007 Jun; 282(24):17501-6. PubMed ID: 17446169
    [TBL] [Abstract][Full Text] [Related]  

  • 15. TopBP1 associates with NBS1 and is involved in homologous recombination repair.
    Morishima K; Sakamoto S; Kobayashi J; Izumi H; Suda T; Matsumoto Y; Tauchi H; Ide H; Komatsu K; Matsuura S
    Biochem Biophys Res Commun; 2007 Nov; 362(4):872-9. PubMed ID: 17765870
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A DNA damage-regulated BRCT-containing protein, TopBP1, is required for cell survival.
    Yamane K; Wu X; Chen J
    Mol Cell Biol; 2002 Jan; 22(2):555-66. PubMed ID: 11756551
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A role for the MRN complex in ATR activation via TOPBP1 recruitment.
    Duursma AM; Driscoll R; Elias JE; Cimprich KA
    Mol Cell; 2013 Apr; 50(1):116-22. PubMed ID: 23582259
    [TBL] [Abstract][Full Text] [Related]  

  • 18. High levels of TopBP1 induce ATR-dependent shut-down of rRNA transcription and nucleolar segregation.
    Sokka M; Rilla K; Miinalainen I; Pospiech H; Syväoja JE
    Nucleic Acids Res; 2015 May; 43(10):4975-89. PubMed ID: 25916852
    [TBL] [Abstract][Full Text] [Related]  

  • 19. ATR activation is regulated by dimerization of ATR activating proteins.
    Thada V; Cortez D
    J Biol Chem; 2021; 296():100455. PubMed ID: 33636182
    [TBL] [Abstract][Full Text] [Related]  

  • 20. RHINO forms a stoichiometric complex with the 9-1-1 checkpoint clamp and mediates ATR-Chk1 signaling.
    Lindsey-Boltz LA; Kemp MG; Capp C; Sancar A
    Cell Cycle; 2015; 14(1):99-108. PubMed ID: 25602520
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.