BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

144 related articles for article (PubMed ID: 37586438)

  • 1. Therapeutic targeting of HYPDH/PRODH2 with N-propargylglycine offers a Hyperoxaluria treatment opportunity.
    Bons J; Tadeo A; Scott GK; Teramayi F; Tanner JJ; Schilling B; Benz CC; Ellerby LM
    Biochim Biophys Acta Mol Basis Dis; 2024 Jan; 1870(1):166848. PubMed ID: 37586438
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The effects of the inactivation of Hydroxyproline dehydrogenase on urinary oxalate and glycolate excretion in mouse models of primary hyperoxaluria.
    Buchalski B; Wood KD; Challa A; Fargue S; Holmes RP; Lowther WT; Knight J
    Biochim Biophys Acta Mol Basis Dis; 2020 Mar; 1866(3):165633. PubMed ID: 31821850
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Proline dehydrogenase 2 (PRODH2) is a hydroxyproline dehydrogenase (HYPDH) and molecular target for treating primary hyperoxaluria.
    Summitt CB; Johnson LC; Jönsson TJ; Parsonage D; Holmes RP; Lowther WT
    Biochem J; 2015 Mar; 466(2):273-81. PubMed ID: 25697095
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Metabolism of [13C5]hydroxyproline in vitro and in vivo: implications for primary hyperoxaluria.
    Jiang J; Johnson LC; Knight J; Callahan MF; Riedel TJ; Holmes RP; Lowther WT
    Am J Physiol Gastrointest Liver Physiol; 2012 Mar; 302(6):G637-43. PubMed ID: 22207577
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Brain transcriptomic, metabolic and mitohormesis properties associated with N-propargylglycine treatment: A prevention strategy against neurodegeneration.
    Teramayi F; Bons J; Scott M; Scott GK; Loureiro A; Lopez-Ramirez A; Schilling B; Ellerby LM; Benz CC
    Brain Res; 2024 Mar; 1826():148733. PubMed ID: 38128812
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A new metabolite of propargylglycine, gamma-glutamylpropargylglycylglycine, in liver of D,L-propargylglycine-administered rats.
    Ohta J; Ubuka T; Kodama H; Sugahara K; Nagamine N
    Biochim Biophys Acta; 1997 Mar; 1334(2-3):240-6. PubMed ID: 9101719
    [TBL] [Abstract][Full Text] [Related]  

  • 7. N-Propargylglycine: a unique suicide inhibitor of proline dehydrogenase with anticancer activity and brain-enhancing mitohormesis properties.
    Scott GK; Mahoney S; Scott M; Loureiro A; Lopez-Ramirez A; Tanner JJ; Ellerby LM; Benz CC
    Amino Acids; 2021 Dec; 53(12):1927-1939. PubMed ID: 34089390
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Genetic cause and prevalence of hydroxyprolinemia.
    Staufner C; Haack TB; Feyh P; Gramer G; Raga DE; Terrile C; Sauer S; Okun JG; Fang-Hoffmann J; Mayatepek E; Prokisch H; Hoffmann GF; Kölker S
    J Inherit Metab Dis; 2016 Sep; 39(5):625-632. PubMed ID: 27139199
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Formation of gamma-glutamylpropargylglycylglycine from propargylglycine in human blood and erythrocytes.
    Nagamine N; Ohta J; Masuoka N; Kodama H; Ubuka T
    Acta Med Okayama; 1999 Feb; 53(1):19-25. PubMed ID: 10096734
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Metabolism of (13)C5-hydroxyproline in mouse models of Primary Hyperoxaluria and its inhibition by RNAi therapeutics targeting liver glycolate oxidase and hydroxyproline dehydrogenase.
    Li X; Knight J; Fargue S; Buchalski B; Guan Z; Inscho EW; Liebow A; Fitzgerald K; Querbes W; Todd Lowther W; Holmes RP
    Biochim Biophys Acta; 2016 Feb; 1862(2):233-9. PubMed ID: 26655602
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Metabolism of cystathionine, N-monoacetylcystathionine, perhydro-1,4-thiazepine-3,5-dicarboxylic acid, and cystathionine ketimine in the liver and kidney of D,L-propargylglycine-treated rats.
    Zhang J; Zhang M; Ma D; Sugahara K; Kodama H
    Metabolism; 1998 Oct; 47(10):1233-8. PubMed ID: 9781627
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Lipid peroxidation is not the underlying cause of renal injury in hyperoxaluric rats.
    Green ML; Freel RW; Hatch M
    Kidney Int; 2005 Dec; 68(6):2629-38. PubMed ID: 16316339
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Hydroxyproline Metabolism and Oxalate Synthesis in Primary Hyperoxaluria.
    Fargue S; Milliner DS; Knight J; Olson JB; Lowther WT; Holmes RP
    J Am Soc Nephrol; 2018 Jun; 29(6):1615-1623. PubMed ID: 29588429
    [No Abstract]   [Full Text] [Related]  

  • 14. Nephrotoxicity of D-proparglyglycine in mice.
    Konno R; Ikeda M; Yamaguchi K; Ueda Y; Niwa A
    Arch Toxicol; 2000 Oct; 74(8):473-9. PubMed ID: 11097385
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Propargylglycine infusion effects on tissue glutathione levels, plasma amino acid concentrations and tissue morphology in parenterally-fed growing rats.
    Cho ES; Hovanec-Brown J; Tomanek RJ; Stegink LD
    J Nutr; 1991 Jun; 121(6):785-94. PubMed ID: 2033464
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Improved methodology to induce hyperoxaluria without treatment using hydroxyproline.
    Wiessner JH; Garrett MR; Hung LY; Wille DF; Mandel NS
    Urol Res; 2011 Oct; 39(5):373-7. PubMed ID: 21373921
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Efficacy of Hydroxy-L-proline (HYP) analogs in the treatment of primary hyperoxaluria in Drosophila Melanogaster.
    Yang H; Male M; Li Y; Wang N; Zhao C; Jin S; Hu J; Chen Z; Ye Z; Xu H
    BMC Nephrol; 2018 Jul; 19(1):167. PubMed ID: 29980178
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Determination of D,L-propargylglycine and N-acetylpropargylglycine in urine and several tissues of D,L-propargylglycine-treated rats using liquid chromatography-mass spectrometry.
    Zhang J; Machida Y; Sugahara K; Kodama H
    J Chromatogr B Biomed Appl; 1994 Oct; 660(2):375-9. PubMed ID: 7866528
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Effect of D,L-propargylglycine on cystathionine metabolism in rats.
    Awata S; Nakayama K; Kodama H
    Biochem Int; 1984 Jan; 8(1):171-9. PubMed ID: 6477595
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Hyperoxaluric rats do not exhibit alterations in renal expression patterns of Slc26a1 (SAT1) mRNA or protein.
    Freel RW; Hatch M
    Urol Res; 2012 Dec; 40(6):647-54. PubMed ID: 22573180
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.