BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

171 related articles for article (PubMed ID: 37592049)

  • 21. Differential effect of acetyltransferase expression on the genotoxicity of heterocyclic amines in CHO cells.
    Wu RW; Tucker JD; Sorensen KJ; Thompson LH; Felton JS
    Mutat Res; 1997 Apr; 390(1-2):93-103. PubMed ID: 9150757
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Effects of dose and human N-acetyltransferase 1 genetic polymorphism in benzidine metabolism and genotoxicity.
    Habil MR; Hein DW
    Arch Toxicol; 2023 Jun; 97(6):1765-1772. PubMed ID: 37097310
    [TBL] [Abstract][Full Text] [Related]  

  • 23. N-acetyltransferase expression and metabolic activation of the food-derived heterocyclic amines in the human mammary gland.
    Sadrieh N; Davis CD; Snyderwine EG
    Cancer Res; 1996 Jun; 56(12):2683-7. PubMed ID: 8665493
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Oral administration of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) yields PhIP-DNA adducts but not tumors in male Syrian hamsters congenic at the N-acetyltransferase 2 (NAT2) locus.
    Fretland AJ; Devanaboyina US; Feng Y; Leff MA; Xiao GH; Webb SJ; Hein DW
    Toxicol Sci; 2001 Feb; 59(2):226-30. PubMed ID: 11158715
    [TBL] [Abstract][Full Text] [Related]  

  • 25. In vitro bioactivation of N-hydroxy-2-amino-alpha-carboline.
    King RS; Teitel CH; Kadlubar FF
    Carcinogenesis; 2000 Jul; 21(7):1347-54. PubMed ID: 10874013
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Rabbit N-acetyltransferase 2 genotyping method to investigate role of acetylation polymorphism on N- and O-acetylation of aromatic and heterocyclic amine carcinogens.
    Hein DW; Doll MA
    Arch Toxicol; 2017 Sep; 91(9):3185-3188. PubMed ID: 28536864
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Metabolic activation of N-hydroxy-2-aminofluorene and N-hydroxy-2-acetylaminofluorene by monomorphic N-acetyltransferase (NAT1) and polymorphic N-acetyltransferase (NAT2) in colon cytosols of Syrian hamsters congenic at the NAT2 locus.
    Hein DW; Doll MA; Gray K; Rustan TD; Ferguson RJ
    Cancer Res; 1993 Feb; 53(3):509-14. PubMed ID: 8425184
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Metabolic activation of heterocyclic aromatic amines catalyzed by human arylamine N-acetyltransferase isozymes (NAT1 and NAT2) expressed in Salmonella typhimurium.
    Wild D; Feser W; Michel S; Lord HL; Josephy PD
    Carcinogenesis; 1995 Mar; 16(3):643-8. PubMed ID: 7697826
    [TBL] [Abstract][Full Text] [Related]  

  • 29. 4-Aminobiphenyl downregulation of NAT2 acetylator genotype-dependent N- and O-acetylation of aromatic and heterocyclic amine carcinogens in primary mammary epithelial cell cultures from rapid and slow acetylator rats.
    Jefferson FA; Xiao GH; Hein DW
    Toxicol Sci; 2009 Jan; 107(1):293-7. PubMed ID: 18842621
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Urinary excretion of unmetabolized and phase II conjugates of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline in humans: relationship to cytochrome P4501A2 and N-acetyltransferase activity.
    Stillwell WG; Kidd LC; Wishnok JS; Tannenbaum SR; Sinha R
    Cancer Res; 1997 Aug; 57(16):3457-64. PubMed ID: 9270013
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Association between dietary heterocyclic amine levels, genetic polymorphisms of NAT2, CYP1A1, and CYP1A2 and risk of stomach cancer: a hospital-based case-control study in Japan.
    Kobayashi M; Otani T; Iwasaki M; Natsukawa S; Shaura K; Koizumi Y; Kasuga Y; Sakamoto H; Yoshida T; Tsugane S
    Gastric Cancer; 2009; 12(4):198-205. PubMed ID: 20047124
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Activation of 3-nitrobenzanthrone and its metabolites by human acetyltransferases, sulfotransferases and cytochrome P450 expressed in Chinese hamster V79 cells.
    Arlt VM; Glatt H; Muckel E; Pabel U; Sorg BL; Seidel A; Frank H; Schmeiser HH; Phillips DH
    Int J Cancer; 2003 Jul; 105(5):583-92. PubMed ID: 12740904
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Differences between human slow N-acetyltransferase 2 alleles in levels of 4-aminobiphenyl-induced DNA adducts and mutations.
    Bendaly J; Doll MA; Millner LM; Metry KJ; Smith NB; Pierce WM; Hein DW
    Mutat Res; 2009 Dec; 671(1-2):13-9. PubMed ID: 19682468
    [TBL] [Abstract][Full Text] [Related]  

  • 34. DNA adduct levels and absence of tumors in female rapid and slow acetylator congenic hamsters administered the rat mammary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine.
    Fretland AJ; Devanaboyina US; Nangju NA; Leff MA; Xiao GH; Webb SJ; Doll MA; Hein DW
    J Biochem Mol Toxicol; 2001; 15(1):26-33. PubMed ID: 11170312
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Catalytic properties and heat stabilities of novel recombinant human N-acetyltransferase 2 allozymes support existence of genetic heterogeneity within the slow acetylator phenotype.
    Hein DW; Doll MA
    Arch Toxicol; 2017 Aug; 91(8):2827-2835. PubMed ID: 28523442
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Structure/function evaluations of single nucleotide polymorphisms in human N-acetyltransferase 2.
    Walraven JM; Zang Y; Trent JO; Hein DW
    Curr Drug Metab; 2008 Jul; 9(6):471-86. PubMed ID: 18680467
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Simultaneous expression of human CYP3A7 and N-acetyltransferase in Chinese hamster CHL cells results in high cytotoxicity for carcinogenic heterocyclic amines.
    Hashimoto H; Yanagawa Y; Sawada M; Itoh S; Deguchi T; Kamataki T
    Arch Biochem Biophys; 1995 Jul; 320(2):323-9. PubMed ID: 7625840
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Prostate-specific human N-acetyltransferase 2 (NAT2) expression in the mouse.
    Leff MA; Epstein PN; Doll MA; Fretland AJ; Devanaboyina US; Rustan TD; Hein DW
    J Pharmacol Exp Ther; 1999 Jul; 290(1):182-7. PubMed ID: 10381774
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Codominant expression of N-acetylation and O-acetylation activities catalyzed by N-acetyltransferase 2 in human hepatocytes.
    Doll MA; Zang Y; Moeller T; Hein DW
    J Pharmacol Exp Ther; 2010 Aug; 334(2):540-4. PubMed ID: 20430842
    [TBL] [Abstract][Full Text] [Related]  

  • 40. A comprehensive approach to the profiling of the cooked meat carcinogens 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, and their metabolites in human urine.
    Gu D; McNaughton L; Lemaster D; Lake BG; Gooderham NJ; Kadlubar FF; Turesky RJ
    Chem Res Toxicol; 2010 Apr; 23(4):788-801. PubMed ID: 20192249
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 9.