173 related articles for article (PubMed ID: 37593784)
1. Pregnane X receptor as a therapeutic target for cholestatic liver injury.
Lan H; Zhang Y; Fan M; Wu B; Wang C
Drug Metab Rev; 2023 Nov; 55(4):371-387. PubMed ID: 37593784
[TBL] [Abstract][Full Text] [Related]
2. Nuclear receptors constitutive androstane receptor and pregnane X receptor ameliorate cholestatic liver injury.
Stedman CA; Liddle C; Coulter SA; Sonoda J; Alvarez JG; Moore DD; Evans RM; Downes M
Proc Natl Acad Sci U S A; 2005 Feb; 102(6):2063-8. PubMed ID: 15684063
[TBL] [Abstract][Full Text] [Related]
3. Nuclear receptors CAR and PXR; therapeutic targets for cholestatic liver disease.
Kakizaki S; Takizawa D; Tojima H; Horiguchi N; Yamazaki Y; Mori M
Front Biosci (Landmark Ed); 2011 Jun; 16(8):2988-3005. PubMed ID: 21622216
[TBL] [Abstract][Full Text] [Related]
4. FXR and PXR: potential therapeutic targets in cholestasis.
Jonker JW; Liddle C; Downes M
J Steroid Biochem Mol Biol; 2012 Jul; 130(3-5):147-58. PubMed ID: 21801835
[TBL] [Abstract][Full Text] [Related]
5. Xenobiotic-sensing nuclear receptors CAR and PXR as drug targets in cholestatic liver disease.
Kakizaki S; Takizawa D; Tojima H; Yamazaki Y; Mori M
Curr Drug Targets; 2009 Nov; 10(11):1156-1163. PubMed ID: 19925451
[TBL] [Abstract][Full Text] [Related]
6. CAR and PXR agonists stimulate hepatic bile acid and bilirubin detoxification and elimination pathways in mice.
Wagner M; Halilbasic E; Marschall HU; Zollner G; Fickert P; Langner C; Zatloukal K; Denk H; Trauner M
Hepatology; 2005 Aug; 42(2):420-30. PubMed ID: 15986414
[TBL] [Abstract][Full Text] [Related]
7. The role of pregnane X receptor (PXR) in substance metabolism.
Lv Y; Luo YY; Ren HW; Li CJ; Xiang ZX; Luan ZL
Front Endocrinol (Lausanne); 2022; 13():959902. PubMed ID: 36111293
[TBL] [Abstract][Full Text] [Related]
8. Regulation of xenobiotic and bile acid metabolism by the nuclear pregnane X receptor.
Kliewer SA; Willson TM
J Lipid Res; 2002 Mar; 43(3):359-64. PubMed ID: 11893771
[TBL] [Abstract][Full Text] [Related]
9. Pregnane X receptor is a target of farnesoid X receptor.
Jung D; Mangelsdorf DJ; Meyer UA
J Biol Chem; 2006 Jul; 281(28):19081-91. PubMed ID: 16682417
[TBL] [Abstract][Full Text] [Related]
10. Nuclear receptors as therapeutic targets in cholestatic liver diseases.
Zollner G; Trauner M
Br J Pharmacol; 2009 Jan; 156(1):7-27. PubMed ID: 19133988
[TBL] [Abstract][Full Text] [Related]
11. The xenobiotic receptors PXR and CAR in liver physiology, an update.
Cai X; Young GM; Xie W
Biochim Biophys Acta Mol Basis Dis; 2021 Jun; 1867(6):166101. PubMed ID: 33600998
[TBL] [Abstract][Full Text] [Related]
12. Lignans from Schisandra sphenanthera protect against lithocholic acid-induced cholestasis by pregnane X receptor activation in mice.
Fan S; Liu C; Jiang Y; Gao Y; Chen Y; Fu K; Yao X; Huang M; Bi H
J Ethnopharmacol; 2019 Dec; 245():112103. PubMed ID: 31336134
[TBL] [Abstract][Full Text] [Related]
13. [Role of PXR and CAR in cholestasis].
Suh JI
Korean J Hepatol; 2006 Mar; 12(1):5-15. PubMed ID: 16565602
[TBL] [Abstract][Full Text] [Related]
14. Picroside II protects against cholestatic liver injury possibly through activation of farnesoid X receptor.
Li T; Xu L; Zheng R; Wang X; Li L; Ji H; Hu Q
Phytomedicine; 2020 Mar; 68():153153. PubMed ID: 32018210
[TBL] [Abstract][Full Text] [Related]
15. Schisandrol B protects against cholestatic liver injury through pregnane X receptors.
Zeng H; Jiang Y; Chen P; Fan X; Li D; Liu A; Ma X; Xie W; Liu P; Gonzalez FJ; Huang M; Bi H
Br J Pharmacol; 2017 Apr; 174(8):672-688. PubMed ID: 28128437
[TBL] [Abstract][Full Text] [Related]
16. Schisandrol B protects against cholestatic liver injury by inhibiting pyroptosis through pregnane X receptor.
Liang H; Yang X; Li H; Wang X; Su H; Li X; Tian J; Cai C; Huang M; Bi H
Biochem Pharmacol; 2022 Oct; 204():115222. PubMed ID: 35988735
[TBL] [Abstract][Full Text] [Related]
17. Pharmacological Activation of PXR and CAR Downregulates Distinct Bile Acid-Metabolizing Intestinal Bacteria and Alters Bile Acid Homeostasis.
Dempsey JL; Wang D; Siginir G; Fei Q; Raftery D; Gu H; Yue Cui J
Toxicol Sci; 2019 Mar; 168(1):40-60. PubMed ID: 30407581
[TBL] [Abstract][Full Text] [Related]
18. Dexamethasone counteracts hepatic inflammation and oxidative stress in cholestatic rats via CAR activation.
Gabbia D; Pozzo L; Zigiotto G; Roverso M; Sacchi D; Dalla Pozza A; Carrara M; Bogialli S; Floreani A; Guido M; De Martin S
PLoS One; 2018; 13(9):e0204336. PubMed ID: 30252871
[TBL] [Abstract][Full Text] [Related]
19. Development of FXR, PXR and CAR agonists and antagonists for treatment of liver disorders.
Fiorucci S; Zampella A; Distrutti E
Curr Top Med Chem; 2012; 12(6):605-24. PubMed ID: 22242859
[TBL] [Abstract][Full Text] [Related]
20. Identifying hepatoprotective mechanism and effective components of Yinchenzhufu decoction in chronic cholestatic liver injury using a comprehensive strategy based on metabolomics, molecular biology, pharmacokinetics, and cytology.
Li Y; Peng X; Wang G; Zan B; Wang Y; Zou J; Tian T; Meng Q; Shi R; Wang T; Wu J; Ma Y
J Ethnopharmacol; 2024 Jan; 319(Pt 1):117060. PubMed ID: 37598769
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
