These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

142 related articles for article (PubMed ID: 37597437)

  • 1. Development of selective class I protein arginine methyltransferase inhibitors through fragment-based drug design approach.
    Bhattacharya D; Shi Ming Li A; Paul B; Ghosh Dastidar U; Santhakumar V; Sarkar D; Chau I; Li F; Ghosh T; Vedadi M; Talukdar A
    Eur J Med Chem; 2023 Nov; 260():115713. PubMed ID: 37597437
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Discovery of a potent and dual-selective bisubstrate inhibitor for protein arginine methyltransferase 4/5.
    Al-Hamashi AA; Chen D; Deng Y; Dong G; Huang R
    Acta Pharm Sin B; 2021 Sep; 11(9):2709-2718. PubMed ID: 34589391
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Turning Nonselective Inhibitors of Type I Protein Arginine Methyltransferases into Potent and Selective Inhibitors of Protein Arginine Methyltransferase 4 through a Deconstruction-Reconstruction and Fragment-Growing Approach.
    Iannelli G; Milite C; Marechal N; Cura V; Bonnefond L; Troffer-Charlier N; Feoli A; Rescigno D; Wang Y; Cipriano A; Viviano M; Bedford MT; Cavarelli J; Castellano S; Sbardella G
    J Med Chem; 2022 Sep; 65(17):11574-11606. PubMed ID: 35482954
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A patent review of arginine methyltransferase inhibitors (2010-2018).
    Li X; Wang C; Jiang H; Luo C
    Expert Opin Ther Pat; 2019 Feb; 29(2):97-114. PubMed ID: 30640571
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A Pan-Inhibitor for Protein Arginine Methyltransferase Family Enzymes.
    Iyamu ID; Al-Hamashi AA; Huang R
    Biomolecules; 2021 Jun; 11(6):. PubMed ID: 34201091
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Discovery of a Potent Class I Protein Arginine Methyltransferase Fragment Inhibitor.
    Ferreira de Freitas R; Eram MS; Szewczyk MM; Steuber H; Smil D; Wu H; Li F; Senisterra G; Dong A; Brown PJ; Hitchcock M; Moosmayer D; Stegmann CM; Egner U; Arrowsmith C; Barsyte-Lovejoy D; Vedadi M; Schapira M
    J Med Chem; 2016 Feb; 59(3):1176-83. PubMed ID: 26824386
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Small Molecule Inhibitors of Protein Arginine Methyltransferases.
    Hu H; Qian K; Ho MC; Zheng YG
    Expert Opin Investig Drugs; 2016; 25(3):335-58. PubMed ID: 26789238
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Discovery of a Potent, Selective, and Cell-Active Dual Inhibitor of Protein Arginine Methyltransferase 4 and Protein Arginine Methyltransferase 6.
    Shen Y; Szewczyk MM; Eram MS; Smil D; Kaniskan HÜ; de Freitas RF; Senisterra G; Li F; Schapira M; Brown PJ; Arrowsmith CH; Barsyte-Lovejoy D; Liu J; Vedadi M; Jin J
    J Med Chem; 2016 Oct; 59(19):9124-9139. PubMed ID: 27584694
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Promising role of protein arginine methyltransferases in overcoming anti-cancer drug resistance.
    Zhu Y; Xia T; Chen DQ; Xiong X; Shi L; Zuo Y; Xiao H; Liu L
    Drug Resist Updat; 2024 Jan; 72():101016. PubMed ID: 37980859
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Rational Design and Synthesis of Selective PRMT4 Inhibitors: A New Chemotype for Development of Cancer Therapeutics*.
    Sutherland M; Li A; Kaghad A; Panagopoulos D; Li F; Szewczyk M; Smil D; Scholten C; Bouché L; Stellfeld T; Arrowsmith CH; Barsyte D; Vedadi M; Hartung IV; Steuber H; Britton R; Santhakumar V
    ChemMedChem; 2021 Apr; 16(7):1116-1125. PubMed ID: 33513288
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Peptidic transition state analogues as PRMT inhibitors.
    Zhang Y; van Haren MJ; Martin NI
    Methods; 2020 Mar; 175():24-29. PubMed ID: 31421210
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Protein arginine methyltransferases: insights into the enzyme structure and mechanism at the atomic level.
    Tewary SK; Zheng YG; Ho MC
    Cell Mol Life Sci; 2019 Aug; 76(15):2917-2932. PubMed ID: 31123777
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Prodrug Approach to Exploit (S)-Alanine Amide as Arginine Mimic Moiety in the Development of Protein Arginine Methyltransferase 4 Inhibitors.
    Milite C; Sarno G; Pacilio I; Cianciulli A; Viviano M; Iannelli G; Gazzillo E; Feoli A; Cipriano A; Giovanna Chini M; Castellano S; Bifulco G; Sbardella G
    ChemMedChem; 2024 Sep; 19(17):e202400139. PubMed ID: 38752332
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Pharmacophore-based virtual screening and biological evaluation of small molecule inhibitors for protein arginine methylation.
    Wang J; Chen L; Sinha SH; Liang Z; Chai H; Muniyan S; Chou YW; Yang C; Yan L; Feng Y; Li KK; Lin MF; Jiang H; Zheng YG; Luo C
    J Med Chem; 2012 Sep; 55(18):7978-87. PubMed ID: 22928876
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Arginine Methylation in Brain Tumors: Tumor Biology and Therapeutic Strategies.
    Bryant JP; Heiss J; Banasavadi-Siddegowda YK
    Cells; 2021 Jan; 10(1):. PubMed ID: 33440687
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Discovery of a Potent and Selective Coactivator Associated Arginine Methyltransferase 1 (CARM1) Inhibitor by Virtual Screening.
    Ferreira de Freitas R; Eram MS; Smil D; Szewczyk MM; Kennedy S; Brown PJ; Santhakumar V; Barsyte-Lovejoy D; Arrowsmith CH; Vedadi M; Schapira M
    J Med Chem; 2016 Jul; 59(14):6838-47. PubMed ID: 27390919
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The macromolecular complexes of histones affect protein arginine methyltransferase activities.
    Fulton MD; Cao M; Ho MC; Zhao X; Zheng YG
    J Biol Chem; 2021 Oct; 297(4):101123. PubMed ID: 34492270
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis and evaluation of protein arginine N-methyltransferase inhibitors designed to simultaneously occupy both substrate binding sites.
    van Haren M; van Ufford LQ; Moret EE; Martin NI
    Org Biomol Chem; 2015 Jan; 13(2):549-60. PubMed ID: 25380215
    [TBL] [Abstract][Full Text] [Related]  

  • 19. An updated patent review of protein arginine N-methyltransferase inhibitors (2019-2022).
    Dong J; Duan J; Hui Z; Garrido C; Deng Z; Xie T; Ye XY
    Expert Opin Ther Pat; 2022 Dec; 32(12):1185-1205. PubMed ID: 36594709
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification, Synthesis, and Biological Evaluations of Potent Inhibitors Targeting Type I Protein Arginine Methyltransferases.
    Li X; Zhang L; Xu J; Liu C; Zhang X; Abdelmoneim AA; Zhang Q; Ke J; Zhang Y; Wang L; Yang F; Luo C; Jin J; Ye F
    J Chem Inf Model; 2022 Feb; 62(3):692-702. PubMed ID: 35098713
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.