BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

126 related articles for article (PubMed ID: 37606185)

  • 1. Anticancer Activities of DNA-Alkylating Pyrrole-Imidazole Polyamide Analogs Targeting RUNX Transcription Factors against
    Hirose Y; Sato S; Hashiya K; Bando T; Sugiyama H
    J Med Chem; 2023 Sep; 66(17):12059-12068. PubMed ID: 37606185
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Molecular Characteristics of DNA-Alkylating PI Polyamides Targeting RUNX Transcription Factors.
    Maeda R; Sato S; Obata S; Ohno T; Hashiya K; Bando T; Sugiyama H
    J Am Chem Soc; 2019 Mar; 141(10):4257-4263. PubMed ID: 30601664
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Evaluation of alkylating pyrrole-imidazole polyamide conjugates by a novel method for high-throughput sequencer.
    Kashiwazaki G; Maeda R; Kawase T; Hashiya K; Bando T; Sugiyama H
    Bioorg Med Chem; 2018 Jan; 26(1):1-7. PubMed ID: 29224995
    [TBL] [Abstract][Full Text] [Related]  

  • 4. DNA Alkylation of the RUNX-Binding Sequence by CBI-PI Polyamide Conjugates*.
    Maeda R; Ito S; Hashiya K; Bando T; Sugiyama H
    Chemistry; 2020 Nov; 26(64):14639-14644. PubMed ID: 32672369
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Genetic regulation of the RUNX transcription factor family has antitumor effects.
    Morita K; Suzuki K; Maeda S; Matsuo A; Mitsuda Y; Tokushige C; Kashiwazaki G; Taniguchi J; Maeda R; Noura M; Hirata M; Kataoka T; Yano A; Yamada Y; Kiyose H; Tokumasu M; Matsuo H; Tanaka S; Okuno Y; Muto M; Naka K; Ito K; Kitamura T; Kaneda Y; Liu PP; Bando T; Adachi S; Sugiyama H; Kamikubo Y
    J Clin Invest; 2017 Jun; 127(7):2815-2828. PubMed ID: 28530640
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Comparative analysis of DNA alkylation by conjugates between pyrrole-imidazole hairpin polyamides and chlorambucil or seco-CBI.
    Minoshima M; Bando T; Shinohara K; Kashiwazaki G; Nishijima S; Sugiyama H
    Bioorg Med Chem; 2010 Feb; 18(3):1236-43. PubMed ID: 20074970
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Sequence-specific DNA alkylation and transcriptional inhibition by long-chain hairpin pyrrole-imidazole polyamide-chlorambucil conjugates targeting CAG/CTG trinucleotide repeats.
    Asamitsu S; Kawamoto Y; Hashiya F; Hashiya K; Yamamoto M; Kizaki S; Bando T; Sugiyama H
    Bioorg Med Chem; 2014 Sep; 22(17):4646-57. PubMed ID: 25127467
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Targeting the mutant PIK3CA gene by DNA-alkylating pyrrole-imidazole polyamide in cervical cancer.
    Krishnamurthy S; Yoda H; Hiraoka K; Inoue T; Lin J; Shinozaki Y; Watanabe T; Koshikawa N; Takatori A; Nagase H
    Cancer Sci; 2021 Mar; 112(3):1141-1149. PubMed ID: 33377228
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Evaluation of the DNA Alkylation Properties of a Chlorambucil-Conjugated Cyclic Pyrrole-Imidazole Polyamide.
    Hirose Y; Hashiya K; Bando T; Sugiyama H
    Chemistry; 2021 Feb; 27(8):2782-2788. PubMed ID: 33145851
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Anticancer activities of alkylating pyrrole-imidazole polyamides with specific sequence recognition.
    Shinohara K; Bando T; Sugiyama H
    Anticancer Drugs; 2010 Mar; 21(3):228-42. PubMed ID: 20038830
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A novel gene silencer, pyrrole-imidazole polyamide targeting human lectin-like oxidized low-density lipoprotein receptor-1 gene improves endothelial cell function.
    Ueno T; Fukuda N; Tsunemi A; Yao EH; Matsuda H; Tahira K; Matsumoto T; Matsumoto K; Matsumoto Y; Nagase H; Sugiyama H; Sawamura T
    J Hypertens; 2009 Mar; 27(3):508-16. PubMed ID: 19330905
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Antitumor effects of pyrrole-imidazole polyamide modified with alkylating agent on prostate cancer cells.
    Funakoshi D; Obinata D; Fujiwara K; Yamamoto S; Takayama K; Hara M; Takahashi S; Inoue S
    Biochem Biophys Res Commun; 2022 Oct; 623():9-16. PubMed ID: 35868070
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Application of DNA-Alkylating Pyrrole-Imidazole Polyamides for Cancer Treatment.
    Maeda R; Bando T; Sugiyama H
    Chembiochem; 2021 May; 22(9):1538-1545. PubMed ID: 33453075
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Use of DNA-alkylating pyrrole-imidazole polyamides for anti-cancer drug sensitivity screening in pancreatic ductal adenocarcinoma.
    Tsujimoto A; Matsuo N; Lai X; Inoue T; Yoda H; Lin J; Shinozaki Y; Watanabe T; Koshikawa N; Takatori A; Nagase H
    Cancer Med; 2023 Mar; 12(5):5821-5832. PubMed ID: 36262061
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A novel gene regulator, pyrrole-imidazole polyamide targeting ABCA1 gene increases cholesterol efflux from macrophages and plasma HDL concentration.
    Tsunemi A; Ueno T; Fukuda N; Watanabe T; Tahira K; Haketa A; Hatanaka Y; Tanaka S; Matsumoto T; Matsumoto Y; Nagase H; Soma M
    J Mol Med (Berl); 2014 May; 92(5):509-21. PubMed ID: 24463557
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and biological properties of pyrrole-imidazole polyamide conjugates.
    Minoshima M; Sasaki S; Fujimoto J; Shinohara K; Bando T; Sugiyama H
    Nucleic Acids Symp Ser (Oxf); 2007; (51):35-6. PubMed ID: 18029573
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Depletion of pro-oncogenic RUNX2 enhances gemcitabine (GEM) sensitivity of p53-mutated pancreatic cancer Panc-1 cells through the induction of pro-apoptotic TAp63.
    Ozaki T; Nakamura M; Ogata T; Sang M; Yoda H; Hiraoka K; Sang M; Shimozato O
    Oncotarget; 2016 Nov; 7(44):71937-71950. PubMed ID: 27713122
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Potent activity against K562 cells by polyamide-seco-CBI conjugates targeting histone H4 genes.
    Minoshima M; Chou JC; Lefebvre S; Bando T; Shinohara K; Gottesfeld JM; Sugiyama H
    Bioorg Med Chem; 2010 Jan; 18(1):168-74. PubMed ID: 19962902
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Targeting a DNA binding motif of the EVI1 protein by a pyrrole-imidazole polyamide.
    Zhang Y; Sicot G; Cui X; Vogel M; Wuertzer CA; Lezon-Geyda K; Wheeler J; Harki DA; Muzikar KA; Stolper DA; Dervan PB; Perkins AS
    Biochemistry; 2011 Dec; 50(48):10431-41. PubMed ID: 22039883
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Molecular design of sequence specific DNA alkylating agents.
    Minoshima M; Bando T; Shinohara K; Sugiyama H
    Nucleic Acids Symp Ser (Oxf); 2009; (53):69-70. PubMed ID: 19749264
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.