BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

256 related articles for article (PubMed ID: 37607000)

  • 21. MED12, the mediator complex subunit 12 gene, is mutated at high frequency in uterine leiomyomas.
    Mäkinen N; Mehine M; Tolvanen J; Kaasinen E; Li Y; Lehtonen HJ; Gentile M; Yan J; Enge M; Taipale M; Aavikko M; Katainen R; Virolainen E; Böhling T; Koski TA; Launonen V; Sjöberg J; Taipale J; Vahteristo P; Aaltonen LA
    Science; 2011 Oct; 334(6053):252-5. PubMed ID: 21868628
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Analysis of
    Lee M; Cheon K; Chae B; Hwang H; Kim HK; Chung YJ; Song JY; Cho HH; Kim JH; Kim MR
    Int J Med Sci; 2018; 15(2):124-128. PubMed ID: 29333096
    [TBL] [Abstract][Full Text] [Related]  

  • 23. MED12 mutation frequency in unselected sporadic uterine leiomyomas.
    Heinonen HR; Sarvilinna NS; Sjöberg J; Kämpjärvi K; Pitkänen E; Vahteristo P; Mäkinen N; Aaltonen LA
    Fertil Steril; 2014 Oct; 102(4):1137-42. PubMed ID: 25108465
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Uterine leiomyoma-linked MED12 mutations disrupt mediator-associated CDK activity.
    Turunen M; Spaeth JM; Keskitalo S; Park MJ; Kivioja T; Clark AD; Mäkinen N; Gao F; Palin K; Nurkkala H; Vähärautio A; Aavikko M; Kämpjärvi K; Vahteristo P; Kim CA; Aaltonen LA; Varjosalo M; Taipale J; Boyer TG
    Cell Rep; 2014 May; 7(3):654-60. PubMed ID: 24746821
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Multiple clinical characteristics separate MED12-mutation-positive and -negative uterine leiomyomas.
    Heinonen HR; Pasanen A; Heikinheimo O; Tanskanen T; Palin K; Tolvanen J; Vahteristo P; Sjöberg J; Pitkänen E; Bützow R; Mäkinen N; Aaltonen LA
    Sci Rep; 2017 Apr; 7(1):1015. PubMed ID: 28432313
    [TBL] [Abstract][Full Text] [Related]  

  • 26. MED12 exon 2 mutations in histopathological uterine leiomyoma variants.
    Mäkinen N; Vahteristo P; Kämpjärvi K; Arola J; Bützow R; Aaltonen LA
    Eur J Hum Genet; 2013 Nov; 21(11):1300-3. PubMed ID: 23443020
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Somatic MED12 mutations in prostate cancer and uterine leiomyomas promote tumorigenesis through distinct mechanisms.
    Kämpjärvi K; Kim NH; Keskitalo S; Clark AD; von Nandelstadh P; Turunen M; Heikkinen T; Park MJ; Mäkinen N; Kivinummi K; Lintula S; Hotakainen K; Nevanlinna H; Hokland P; Böhling T; Bützow R; Böhm J; Mecklin JP; Järvinen H; Kontro M; Visakorpi T; Taipale J; Varjosalo M; Boyer TG; Vahteristo P
    Prostate; 2016 Jan; 76(1):22-31. PubMed ID: 26383637
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Tryptophan metabolism induced by TDO2 promotes prostatic cancer chemotherapy resistance in a AhR/c-Myc dependent manner.
    Li F; Zhao Z; Zhang Z; Zhang Y; Guan W
    BMC Cancer; 2021 Oct; 21(1):1112. PubMed ID: 34657603
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Mutational analysis of MED12 exon 2 in uterine leiomyoma and other common tumors.
    Je EM; Kim MR; Min KO; Yoo NJ; Lee SH
    Int J Cancer; 2012 Sep; 131(6):E1044-7. PubMed ID: 22532225
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Epidemiological and genetic clues for molecular mechanisms involved in uterine leiomyoma development and growth.
    Commandeur AE; Styer AK; Teixeira JM
    Hum Reprod Update; 2015; 21(5):593-615. PubMed ID: 26141720
    [TBL] [Abstract][Full Text] [Related]  

  • 31. MED12 and uterine smooth muscle oncogenesis: State of the art and perspectives.
    Croce S; Chibon F
    Eur J Cancer; 2015 Aug; 51(12):1603-10. PubMed ID: 26037152
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Med12 gain-of-function mutation causes leiomyomas and genomic instability.
    Mittal P; Shin YH; Yatsenko SA; Castro CA; Surti U; Rajkovic A
    J Clin Invest; 2015 Aug; 125(8):3280-4. PubMed ID: 26193636
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Characterization of MED12, HMGA2, and FH alterations reveals molecular variability in uterine smooth muscle tumors.
    Mäkinen N; Kämpjärvi K; Frizzell N; Bützow R; Vahteristo P
    Mol Cancer; 2017 Jun; 16(1):101. PubMed ID: 28592321
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Missense mutations in exon 2 of the MED12 gene are involved in IGF-2 overexpression in uterine leiomyoma.
    Di Tommaso S; Tinelli A; Malvasi A; Massari S
    Mol Hum Reprod; 2014 Oct; 20(10):1009-15. PubMed ID: 25015674
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Investigation of the aryl hydrocarbon receptor and the intrinsic tumoral component of the kynurenine pathway of tryptophan metabolism in primary brain tumors.
    Guastella AR; Michelhaugh SK; Klinger NV; Fadel HA; Kiousis S; Ali-Fehmi R; Kupsky WJ; Juhász C; Mittal S
    J Neurooncol; 2018 Sep; 139(2):239-249. PubMed ID: 29667084
    [TBL] [Abstract][Full Text] [Related]  

  • 36. The study of MED12 gene mutations in uterine leiomyomas from Iranian patients.
    Sadeghi S; Khorrami M; Amin-Beidokhti M; Abbasi M; Kamalian Z; Irani S; Omrani M; Azmoodeh O; Mirfakhraie R
    Tumour Biol; 2016 Feb; 37(2):1567-71. PubMed ID: 26298726
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Targeting the IDO1/TDO2-KYN-AhR Pathway for Cancer Immunotherapy - Challenges and Opportunities.
    Cheong JE; Sun L
    Trends Pharmacol Sci; 2018 Mar; 39(3):307-325. PubMed ID: 29254698
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Targeting of neuroblastoma cells through Kynurenine-AHR pathway inhibition.
    Dos Santos IL; Mitchell M; Nogueira PAS; Lafita-Navarro MC; Perez-Castro L; Eriom J; Kilgore JA; Williams NS; Guo L; Xu L; Conacci-Sorrell M
    FEBS J; 2024 May; 291(10):2172-2190. PubMed ID: 38431776
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Whole exome sequencing in a random sample of North American women with leiomyomas identifies MED12 mutations in majority of uterine leiomyomas.
    McGuire MM; Yatsenko A; Hoffner L; Jones M; Surti U; Rajkovic A
    PLoS One; 2012; 7(3):e33251. PubMed ID: 22428002
    [TBL] [Abstract][Full Text] [Related]  

  • 40. MED12 mutations and FH inactivation are mutually exclusive in uterine leiomyomas.
    Kämpjärvi K; Mäkinen N; Mehine M; Välipakka S; Uimari O; Pitkänen E; Heinonen HR; Heikkinen T; Tolvanen J; Ahtikoski A; Frizzell N; Sarvilinna N; Sjöberg J; Bützow R; Aaltonen LA; Vahteristo P
    Br J Cancer; 2016 Jun; 114(12):1405-11. PubMed ID: 27187686
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 13.