128 related articles for article (PubMed ID: 37609887)
1. Mechanistic aspects of reactive metabolite formation in clomethiazole catalyzed biotransformation by cytochrome P450 enzymes.
Kamel EM; Tawfeek AM; El-Bassuony AA; Lamsabhi AM
Org Biomol Chem; 2023 Sep; 21(35):7158-7172. PubMed ID: 37609887
[TBL] [Abstract][Full Text] [Related]
2. Reactive Metabolites from Thiazole-Containing Drugs: Quantum Chemical Insights into Biotransformation and Toxicity.
Jaladanki CK; Khatun S; Gohlke H; Bharatam PV
Chem Res Toxicol; 2021 Jun; 34(6):1503-1517. PubMed ID: 33900062
[TBL] [Abstract][Full Text] [Related]
3. Identification of the human and rat P450 enzymes responsible for the sulfoxidation of S-methyl N,N-diethylthiolcarbamate (DETC-ME). The terminal step in the bioactivation of disulfiram.
Madan A; Parkinson A; Faiman MD
Drug Metab Dispos; 1995 Oct; 23(10):1153-62. PubMed ID: 8654205
[TBL] [Abstract][Full Text] [Related]
4. Computational insight into biotransformation of halophenols by cytochrome P450: Mechanism and reactivity for epoxidation.
Han C; Zhu W; Ma G; Chen Y; Li X; Wei X; Yu H
Chemosphere; 2022 Jan; 286(Pt 2):131708. PubMed ID: 34352543
[TBL] [Abstract][Full Text] [Related]
5. The biotransformation of isoprene and the two isoprene monoepoxides by human cytochrome P450 enzymes, compared to mouse and rat liver microsomes.
Bogaards JJ; Venekamp JC; van Bladeren PJ
Chem Biol Interact; 1996 Dec; 102(3):169-82. PubMed ID: 9021169
[TBL] [Abstract][Full Text] [Related]
6. Chlormethiazole inhibition of cytochrome P450 2E1 as assessed by chlorzoxazone hydroxylation in humans.
Gebhardt AC; Lucas D; Ménez JF; Seitz HK
Hepatology; 1997 Oct; 26(4):957-61. PubMed ID: 9328319
[TBL] [Abstract][Full Text] [Related]
7. Biotransformation of Bisphenol by Human Cytochrome P450 2C9 Enzymes: A Density Functional Theory Study.
Hermano Sampaio Dias A; Yadav R; Mokkawes T; Kumar A; Skaf MS; Sastri CV; Kumar D; de Visser SP
Inorg Chem; 2023 Feb; 62(5):2244-2256. PubMed ID: 36651185
[TBL] [Abstract][Full Text] [Related]
8. Identification of the human P-450 enzymes responsible for the sulfoxidation and thiono-oxidation of diethyldithiocarbamate methyl ester: role of P-450 enzymes in disulfiram bioactivation.
Madan A; Parkinson A; Faiman MD
Alcohol Clin Exp Res; 1998 Sep; 22(6):1212-9. PubMed ID: 9756035
[TBL] [Abstract][Full Text] [Related]
9. Metabolic-intermediate complex formation with cytochrome P450: theoretical studies in elucidating the reaction pathway for the generation of reactive nitroso intermediate.
Taxak N; Desai PV; Patel B; Mohutsky M; Klimkowski VJ; Gombar V; Bharatam PV
J Comput Chem; 2012 Aug; 33(21):1740-7. PubMed ID: 22610824
[TBL] [Abstract][Full Text] [Related]
10. Metabolism of the active metabolite of quetiapine, N-desalkylquetiapine in vitro.
Bakken GV; Molden E; Knutsen K; Lunder N; Hermann M
Drug Metab Dispos; 2012 Sep; 40(9):1778-84. PubMed ID: 22688609
[TBL] [Abstract][Full Text] [Related]
11. Mechanism-based inactivation of cytochromes by furan epoxide: unraveling the molecular mechanism.
Taxak N; Kalra S; Bharatam PV
Inorg Chem; 2013 Dec; 52(23):13496-508. PubMed ID: 24236636
[TBL] [Abstract][Full Text] [Related]
12. Bio-activation of 4-alkyl analogs of 1,4-dihydropyridine mediated by cytochrome P450 enzymes.
Li XX; Zhang X; Zheng QC; Wang Y
J Biol Inorg Chem; 2015 Jun; 20(4):665-73. PubMed ID: 25783494
[TBL] [Abstract][Full Text] [Related]
13. Identification of human liver cytochrome P450 enzymes that metabolize the nonsedating antihistamine loratadine. Formation of descarboethoxyloratadine by CYP3A4 and CYP2D6.
Yumibe N; Huie K; Chen KJ; Snow M; Clement RP; Cayen MN
Biochem Pharmacol; 1996 Jan; 51(2):165-72. PubMed ID: 8615885
[TBL] [Abstract][Full Text] [Related]
14. Selective Time- and NADPH-Dependent Inhibition of Human CYP2E1 by Clomethiazole.
Stresser DM; Perloff ES; Mason AK; Blanchard AP; Dehal SS; Creegan TP; Singh R; Gangl ET
Drug Metab Dispos; 2016 Aug; 44(8):1424-30. PubMed ID: 27149898
[TBL] [Abstract][Full Text] [Related]
15. Mechanism-Based Inactivation of Cytochrome P450 3A4 by Benzbromarone.
Tang LWT; Verma RK; Fan H; Chan ECY
Mol Pharmacol; 2021 Apr; 99(4):266-276. PubMed ID: 33436520
[TBL] [Abstract][Full Text] [Related]
16. Human liver carbamazepine metabolism. Role of CYP3A4 and CYP2C8 in 10,11-epoxide formation.
Kerr BM; Thummel KE; Wurden CJ; Klein SM; Kroetz DL; Gonzalez FJ; Levy RH
Biochem Pharmacol; 1994 Jun; 47(11):1969-79. PubMed ID: 8010982
[TBL] [Abstract][Full Text] [Related]
17. Covalent thiol adducts arising from reactive intermediates of cocaine biotransformation.
Schneider KJ; DeCaprio AP
Chem Res Toxicol; 2013 Nov; 26(11):1755-64. PubMed ID: 24112049
[TBL] [Abstract][Full Text] [Related]
18. In vitro biotransformation and identification of human cytochrome P450 isozyme-dependent metabolism of tazofelone.
Surapaneni SS; Clay MP; Spangle LA; Paschal JW; Lindstrom TD
Drug Metab Dispos; 1997 Dec; 25(12):1383-8. PubMed ID: 9394028
[TBL] [Abstract][Full Text] [Related]
19. Theoretical study on the metabolic mechanisms of levmepromazine by cytochrome P450.
Wang Y; Chen Q; Xue Z; Zhang Y; Chen Z; Xue Y
J Mol Model; 2016 Oct; 22(10):237. PubMed ID: 27624166
[TBL] [Abstract][Full Text] [Related]
20. Examination of microsomal cytochrome P450-catalyzed in vitro activation of o-phenylphenol to DNA binding metabolite(s) by 32P-postlabeling technique.
Pathak DN; Roy D
Carcinogenesis; 1992 Sep; 13(9):1593-7. PubMed ID: 1394845
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]