BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

202 related articles for article (PubMed ID: 37626063)

  • 1. Whole genomic analysis reveals atypical non-homologous off-target large structural variants induced by CRISPR-Cas9-mediated genome editing.
    Tsai HH; Kao HJ; Kuo MW; Lin CH; Chang CM; Chen YY; Chen HH; Kwok PY; Yu AL; Yu J
    Nat Commun; 2023 Aug; 14(1):5183. PubMed ID: 37626063
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Low incidence of SNVs and indels in trio genomes of Cas9-mediated multiplex edited sheep.
    Wang X; Liu J; Niu Y; Li Y; Zhou S; Li C; Ma B; Kou Q; Petersen B; Sonstegard T; Huang X; Jiang Y; Chen Y
    BMC Genomics; 2018 May; 19(1):397. PubMed ID: 29801435
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cas9 Cuts and Consequences; Detecting, Predicting, and Mitigating CRISPR/Cas9 On- and Off-Target Damage: Techniques for Detecting, Predicting, and Mitigating the On- and off-target Effects of Cas9 Editing.
    Newman A; Starrs L; Burgio G
    Bioessays; 2020 Sep; 42(9):e2000047. PubMed ID: 32643177
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Amplification-free long-read sequencing reveals unforeseen CRISPR-Cas9 off-target activity.
    Höijer I; Johansson J; Gudmundsson S; Chin CS; Bunikis I; Häggqvist S; Emmanouilidou A; Wilbe M; den Hoed M; Bondeson ML; Feuk L; Gyllensten U; Ameur A
    Genome Biol; 2020 Dec; 21(1):290. PubMed ID: 33261648
    [TBL] [Abstract][Full Text] [Related]  

  • 5. [Mechanisms of the Specificity of the CRISPR/Cas9 System in Genome Editing].
    Kulishova LM; Vokhtantsev IP; Kim DV; Zharkov DO
    Mol Biol (Mosk); 2023; 57(2):269-284. PubMed ID: 37000655
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Optimized paired-sgRNA/Cas9 cloning and expression cassette triggers high-efficiency multiplex genome editing in kiwifruit.
    Wang Z; Wang S; Li D; Zhang Q; Li L; Zhong C; Liu Y; Huang H
    Plant Biotechnol J; 2018 Aug; 16(8):1424-1433. PubMed ID: 29331077
    [TBL] [Abstract][Full Text] [Related]  

  • 7. CRISPR-Cas9 induces large structural variants at on-target and off-target sites in vivo that segregate across generations.
    Höijer I; Emmanouilidou A; Östlund R; van Schendel R; Bozorgpana S; Tijsterman M; Feuk L; Gyllensten U; den Hoed M; Ameur A
    Nat Commun; 2022 Feb; 13(1):627. PubMed ID: 35110541
    [TBL] [Abstract][Full Text] [Related]  

  • 8. CRISPRroots: on- and off-target assessment of RNA-seq data in CRISPR-Cas9 edited cells.
    Corsi GI; Gadekar VP; Gorodkin J; Seemann SE
    Nucleic Acids Res; 2022 Feb; 50(4):e20. PubMed ID: 34850137
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Non-homologous end-joining-deficient filamentous fungal strains mitigate the impact of off-target mutations during the application of CRISPR/Cas9.
    Garrigues S; Peng M; Kun RS; de Vries RP
    mBio; 2023 Aug; 14(4):e0066823. PubMed ID: 37486124
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification of genomic sites for CRISPR/Cas9-based genome editing in the Vitis vinifera genome.
    Wang Y; Liu X; Ren C; Zhong GY; Yang L; Li S; Liang Z
    BMC Plant Biol; 2016 Apr; 16():96. PubMed ID: 27098585
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Gene Therapy with CRISPR/Cas9 Coming to Age for HIV Cure.
    Soriano V
    AIDS Rev; 2017; 19(3):167-172. PubMed ID: 29019352
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Scaffold-mediated non-viral delivery platform for CRISPR/Cas9-based genome editing.
    Chin JS; Chooi WH; Wang H; Ong W; Leong KW; Chew SY
    Acta Biomater; 2019 May; 90():60-70. PubMed ID: 30978509
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Whole genome analysis for 163 gRNAs in Cas9-edited mice reveals minimal off-target activity.
    Peterson KA; Khalouei S; Hanafi N; Wood JA; Lanza DG; Lintott LG; Willis BJ; Seavitt JR; Braun RE; Dickinson ME; White JK; Lloyd KCK; Heaney JD; Murray SA; Ramani A; Nutter LMJ
    Commun Biol; 2023 Jun; 6(1):626. PubMed ID: 37301944
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Introducing Large Genomic Deletions in Human Pluripotent Stem Cells Using CRISPR-Cas3.
    Hou Z; Hu C; Ke A; Zhang Y
    Curr Protoc; 2022 Feb; 2(2):e361. PubMed ID: 35129865
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Optical Genome Mapping Reveals Genomic Alterations upon Gene Editing in hiPSCs: Implications for Neural Tissue Differentiation and Brain Organoid Research.
    Gallego Villarejo L; Gerding WM; Bachmann L; Hardt LHI; Bormann S; Nguyen HP; Müller T
    Cells; 2024 Mar; 13(6):. PubMed ID: 38534351
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Precise homology-directed installation of large genomic edits in human cells with cleaving and nicking high-specificity Cas9 variants.
    Wang Q; Liu J; Janssen JM; Gonçalves MAFV
    Nucleic Acids Res; 2023 Apr; 51(7):3465-3484. PubMed ID: 36928106
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Computational Tools and Resources for CRISPR/Cas Genome Editing.
    Li C; Chu W; Gill RA; Sang S; Shi Y; Hu X; Yang Y; Zaman QU; Zhang B
    Genomics Proteomics Bioinformatics; 2023 Feb; 21(1):108-126. PubMed ID: 35341983
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Utilizing directed evolution to interrogate and optimize CRISPR/Cas guide RNA scaffolds.
    Bush K; Corsi GI; Yan AC; Haynes K; Layzer JM; Zhou JH; Llanga T; Gorodkin J; Sullenger BA
    Cell Chem Biol; 2023 Aug; 30(8):879-892.e5. PubMed ID: 37390831
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Verification of CRISPR editing and finding transgenic inserts by Xdrop indirect sequence capture followed by short- and long-read sequencing.
    Blondal T; Gamba C; Møller Jagd L; Su L; Demirov D; Guo S; Johnston CM; Riising EM; Wu X; Mikkelsen MJ; Szabova L; Mouritzen P
    Methods; 2021 Jul; 191():68-77. PubMed ID: 33582298
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Crispr/Cas9-mediated cleavages facilitate homologous recombination during genetic engineering of a large chromosomal region.
    Zhang F; Cheng D; Wang S; Zhu J
    Biotechnol Bioeng; 2020 Sep; 117(9):2816-2826. PubMed ID: 32449788
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.