161 related articles for article (PubMed ID: 37626065)
1. LZTR1 deficiency exerts high metastatic potential by enhancing sensitivity to EMT induction and controlling KLHL12-mediated collagen secretion.
Abe T; Kanno SI; Niihori T; Terao M; Takada S; Aoki Y
Cell Death Dis; 2023 Aug; 14(8):556. PubMed ID: 37626065
[TBL] [Abstract][Full Text] [Related]
2. Structural Model for Recruitment of RIT1 to the LZTR1 E3 Ligase: Evidences from an Integrated Computational Approach.
Paladino A; D'Angelo F; Noviello TMR; Iavarone A; Ceccarelli M
J Chem Inf Model; 2021 Apr; 61(4):1875-1888. PubMed ID: 33792302
[TBL] [Abstract][Full Text] [Related]
3. LZTR1 facilitates polyubiquitination and degradation of RAS-GTPases.
Abe T; Umeki I; Kanno SI; Inoue SI; Niihori T; Aoki Y
Cell Death Differ; 2020 Mar; 27(3):1023-1035. PubMed ID: 31337872
[TBL] [Abstract][Full Text] [Related]
4. Dominant Noonan syndrome-causing LZTR1 mutations specifically affect the Kelch domain substrate-recognition surface and enhance RAS-MAPK signaling.
Motta M; Fidan M; Bellacchio E; Pantaleoni F; Schneider-Heieck K; Coppola S; Borck G; Salviati L; Zenker M; Cirstea IC; Tartaglia M
Hum Mol Genet; 2019 Mar; 28(6):1007-1022. PubMed ID: 30481304
[TBL] [Abstract][Full Text] [Related]
5. KLHL12 can form large COPII structures in the absence of CUL3 neddylation.
Moretti T; Kim K; Tuladhar A; Kim J
Mol Biol Cell; 2023 Mar; 34(3):br4. PubMed ID: 36652337
[TBL] [Abstract][Full Text] [Related]
6. Mutations in LZTR1 drive human disease by dysregulating RAS ubiquitination.
Steklov M; Pandolfi S; Baietti MF; Batiuk A; Carai P; Najm P; Zhang M; Jang H; Renzi F; Cai Y; Abbasi Asbagh L; Pastor T; De Troyer M; Simicek M; Radaelli E; Brems H; Legius E; Tavernier J; Gevaert K; Impens F; Messiaen L; Nussinov R; Heymans S; Eyckerman S; Sablina AA
Science; 2018 Dec; 362(6419):1177-1182. PubMed ID: 30442762
[TBL] [Abstract][Full Text] [Related]
7. Cross-species analysis of LZTR1 loss-of-function mutants demonstrates dependency to RIT1 orthologs.
Cuevas-Navarro A; Rodriguez-Muñoz L; Grego-Bessa J; Cheng A; Rauen KA; Urisman A; McCormick F; Jimenez G; Castel P
Elife; 2022 Apr; 11():. PubMed ID: 35467524
[TBL] [Abstract][Full Text] [Related]
8. LZTR1: A promising adaptor of the CUL3 family.
Zhang H; Cao X; Wang J; Li Q; Zhao Y; Jin X
Oncol Lett; 2021 Jul; 22(1):564. PubMed ID: 34113392
[TBL] [Abstract][Full Text] [Related]
9. Identification of a PGXPP degron motif in dishevelled and structural basis for its binding to the E3 ligase KLHL12.
Chen Z; Wasney GA; Picaud S; Filippakopoulos P; Vedadi M; D'Angiolella V; Bullock AN
Open Biol; 2020 Jun; 10(6):200041. PubMed ID: 32574548
[TBL] [Abstract][Full Text] [Related]
10. The microRNA-200/Zeb1 axis regulates ECM-dependent β1-integrin/FAK signaling, cancer cell invasion and metastasis through CRKL.
Ungewiss C; Rizvi ZH; Roybal JD; Peng DH; Gold KA; Shin DH; Creighton CJ; Gibbons DL
Sci Rep; 2016 Jan; 6():18652. PubMed ID: 26728244
[TBL] [Abstract][Full Text] [Related]
11. Cullin 3 and Its Role in Tumorigenesis.
Chen RH
Adv Exp Med Biol; 2020; 1217():187-210. PubMed ID: 31898229
[TBL] [Abstract][Full Text] [Related]
12. Ubiquitin-dependent regulation of COPII coat size and function.
Jin L; Pahuja KB; Wickliffe KE; Gorur A; Baumgärtel C; Schekman R; Rape M
Nature; 2012 Feb; 482(7386):495-500. PubMed ID: 22358839
[TBL] [Abstract][Full Text] [Related]
13. Role of Wnt Inhibitory Factor-1 in Inhibition of Bisdemethoxycurcumin Mediated Epithelial-to-Mesenchymal Transition in Highly Metastatic Lung Cancer 95D Cells.
Xu JH; Yang HP; Zhou XD; Wang HJ; Gong L; Tang CL
Chin Med J (Engl); 2015 May; 128(10):1376-83. PubMed ID: 25963361
[TBL] [Abstract][Full Text] [Related]
14. Impaired Proteolysis of Noncanonical RAS Proteins Drives Clonal Hematopoietic Transformation.
Chen S; Vedula RS; Cuevas-Navarro A; Lu B; Hogg SJ; Wang E; Benbarche S; Knorr K; Kim WJ; Stanley RF; Cho H; Erickson C; Singer M; Cui D; Tittley S; Durham BH; Pavletich TS; Fiala E; Walsh MF; Inoue D; Monette S; Taylor J; Rosen N; McCormick F; Lindsley RC; Castel P; Abdel-Wahab O
Cancer Discov; 2022 Oct; 12(10):2434-2453. PubMed ID: 35904492
[TBL] [Abstract][Full Text] [Related]
15. SPARC acts as a mediator of TGF-β1 in promoting epithelial-to-mesenchymal transition in A549 and H1299 lung cancer cells.
Sun W; Feng J; Yi Q; Xu X; Chen Y; Tang L
Biofactors; 2018 Sep; 44(5):453-464. PubMed ID: 30346081
[TBL] [Abstract][Full Text] [Related]
16. UBE2C, Directly Targeted by miR-548e-5p, Increases the Cellular Growth and Invasive Abilities of Cancer Cells Interacting with the EMT Marker Protein Zinc Finger E-box Binding Homeobox 1/2 in NSCLC.
Jin D; Guo J; Wu Y; Du J; Wang X; An J; Hu B; Kong L; Di W; Wang W
Theranostics; 2019; 9(7):2036-2055. PubMed ID: 31037155
[No Abstract] [Full Text] [Related]
17. LncRNA LL22NC03-N14H11.1 promoted hepatocellular carcinoma progression through activating MAPK pathway to induce mitochondrial fission.
Yi T; Luo H; Qin F; Jiang Q; He S; Wang T; Su J; Song S; Qin X; Qin Y; Zhou X; Huang Z
Cell Death Dis; 2020 Oct; 11(10):832. PubMed ID: 33028809
[TBL] [Abstract][Full Text] [Related]
18. LZTR1 is a regulator of RAS ubiquitination and signaling.
Bigenzahn JW; Collu GM; Kartnig F; Pieraks M; Vladimer GI; Heinz LX; Sedlyarov V; Schischlik F; Fauster A; Rebsamen M; Parapatics K; Blomen VA; Müller AC; Winter GE; Kralovics R; Brummelkamp TR; Mlodzik M; Superti-Furga G
Science; 2018 Dec; 362(6419):1171-1177. PubMed ID: 30442766
[TBL] [Abstract][Full Text] [Related]
19. Generation of a Mouse Model to Study the Noonan Syndrome Gene
Talley MJ; Nardini D; Shabbir N; Ehrman LA; Prada CE; Waclaw RR
Front Cell Dev Biol; 2021; 9():673995. PubMed ID: 34222248
[TBL] [Abstract][Full Text] [Related]
20. Chinese medicine Bu-Fei decoction attenuates epithelial-mesenchymal transition of non-small cell lung cancer via inhibition of transforming growth factor β1 signaling pathway in vitro and in vivo.
He XR; Han SY; Li XH; Zheng WX; Pang LN; Jiang ST; Li PP
J Ethnopharmacol; 2017 May; 204():45-57. PubMed ID: 28412214
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]