275 related articles for article (PubMed ID: 37626123)
1. MLL-AF4 cooperates with PAF1 and FACT to drive high-density enhancer interactions in leukemia.
Crump NT; Smith AL; Godfrey L; Dopico-Fernandez AM; Denny N; Harman JR; Hamley JC; Jackson NE; Chahrour C; Riva S; Rice S; Kim J; Basrur V; Fermin D; Elenitoba-Johnson K; Roeder RG; Allis CD; Roberts I; Roy A; Geng H; Davies JOJ; Milne TA
Nat Commun; 2023 Aug; 14(1):5208. PubMed ID: 37626123
[TBL] [Abstract][Full Text] [Related]
2. H3K79me2/3 controls enhancer-promoter interactions and activation of the pan-cancer stem cell marker PROM1/CD133 in MLL-AF4 leukemia cells.
Godfrey L; Crump NT; O'Byrne S; Lau IJ; Rice S; Harman JR; Jackson T; Elliott N; Buck G; Connor C; Thorne R; Knapp DJHF; Heidenreich O; Vyas P; Menendez P; Inglott S; Ancliff P; Geng H; Roberts I; Roy A; Milne TA
Leukemia; 2021 Jan; 35(1):90-106. PubMed ID: 32242051
[TBL] [Abstract][Full Text] [Related]
3. AF4 and AF4-MLL mediate transcriptional elongation of 5-lipoxygenase mRNA by 1, 25-dihydroxyvitamin D3.
Ahmad K; Scholz B; Capelo R; Schweighöfer I; Kahnt AS; Marschalek R; Steinhilber D
Oncotarget; 2015 Sep; 6(28):25784-800. PubMed ID: 26329759
[TBL] [Abstract][Full Text] [Related]
4. t(4;11) leukemias display addiction to MLL-AF4 but not to AF4-MLL.
Kumar AR; Yao Q; Li Q; Sam TA; Kersey JH
Leuk Res; 2011 Mar; 35(3):305-9. PubMed ID: 20869771
[TBL] [Abstract][Full Text] [Related]
5. MLL-AF4 binds directly to a BCL-2 specific enhancer and modulates H3K27 acetylation.
Godfrey L; Kerry J; Thorne R; Repapi E; Davies JO; Tapia M; Ballabio E; Hughes JR; Geng H; Konopleva M; Milne TA
Exp Hematol; 2017 Mar; 47():64-75. PubMed ID: 27856324
[TBL] [Abstract][Full Text] [Related]
6. MLL-AF9 and MLL-AF4 oncofusion proteins bind a distinct enhancer repertoire and target the RUNX1 program in 11q23 acute myeloid leukemia.
Prange KHM; Mandoli A; Kuznetsova T; Wang SY; Sotoca AM; Marneth AE; van der Reijden BA; Stunnenberg HG; Martens JHA
Oncogene; 2017 Jun; 36(23):3346-3356. PubMed ID: 28114278
[TBL] [Abstract][Full Text] [Related]
7. Crosstalk between 14-3-3θ and AF4 enhances MLL-AF4 activity and promotes leukemia cell proliferation.
Fioretti T; Cevenini A; Zanobio M; Raia M; Sarnataro D; Salvatore F; Esposito G
Cell Oncol (Dordr); 2019 Dec; 42(6):829-845. PubMed ID: 31493143
[TBL] [Abstract][Full Text] [Related]
8. Sensitivity of MLL-rearranged AML cells to all-trans retinoic acid is associated with the level of H3K4me2 in the RARα promoter region.
Sakamoto K; Imamura T; Yano M; Yoshida H; Fujiki A; Hirashima Y; Hosoi H
Blood Cancer J; 2014 Apr; 4(4):e205. PubMed ID: 24769646
[TBL] [Abstract][Full Text] [Related]
9. circRNA circAF4 functions as an oncogene to regulate MLL-AF4 fusion protein expression and inhibit MLL leukemia progression.
Huang W; Fang K; Chen TQ; Zeng ZC; Sun YM; Han C; Sun LY; Chen ZH; Yang QQ; Pan Q; Luo XQ; Wang WT; Chen YQ
J Hematol Oncol; 2019 Oct; 12(1):103. PubMed ID: 31623653
[TBL] [Abstract][Full Text] [Related]
10. The mixed lineage leukemia (MLL) fusion-associated gene AF4 promotes CD133 transcription.
Mak AB; Nixon AM; Moffat J
Cancer Res; 2012 Apr; 72(8):1929-34. PubMed ID: 22337994
[TBL] [Abstract][Full Text] [Related]
11. Methylation-mediated repression of microRNA-143 enhances MLL-AF4 oncogene expression.
Dou L; Zheng D; Li J; Li Y; Gao L; Wang L; Yu L
Oncogene; 2012 Jan; 31(4):507-17. PubMed ID: 21706045
[TBL] [Abstract][Full Text] [Related]
12. MicroRNA-142-3p inhibits cell proliferation in human acute lymphoblastic leukemia by targeting the MLL-AF4 oncogene.
Dou L; Li J; Zheng D; Li Y; Gao X; Xu C; Gao L; Wang L; Yu L
Mol Biol Rep; 2013 Dec; 40(12):6811-9. PubMed ID: 24057258
[TBL] [Abstract][Full Text] [Related]
13. miR-130b and miR-128a are essential lineage-specific codrivers of t(4;11) MLL-AF4 acute leukemia.
Malouf C; Antunes ETB; O'Dwyer M; Jakobczyk H; Sahm F; Landua SL; Anderson RA; Soufi A; Halsey C; Ottersbach K
Blood; 2021 Nov; 138(21):2066-2092. PubMed ID: 34111240
[TBL] [Abstract][Full Text] [Related]
14. MLL-AF4 Spreading Identifies Binding Sites that Are Distinct from Super-Enhancers and that Govern Sensitivity to DOT1L Inhibition in Leukemia.
Kerry J; Godfrey L; Repapi E; Tapia M; Blackledge NP; Ma H; Ballabio E; O'Byrne S; Ponthan F; Heidenreich O; Roy A; Roberts I; Konopleva M; Klose RJ; Geng H; Milne TA
Cell Rep; 2017 Jan; 18(2):482-495. PubMed ID: 28076791
[TBL] [Abstract][Full Text] [Related]
15. Molecular characterization of a rare MLL-AF4 (MLL-AFF1) fusion rearrangement in infant leukemia.
Bizarro S; Cerveira N; Correia C; Lisboa S; Peixoto A; Norton L; Teixeira MR
Cancer Genet Cytogenet; 2007 Oct; 178(1):61-4. PubMed ID: 17889710
[TBL] [Abstract][Full Text] [Related]
16. Identification of genes transcriptionally responsive to the loss of MLL fusions in MLL-rearranged acute lymphoblastic leukemia.
van der Linden MH; Seslija L; Schneider P; Driessen EM; Castro PG; Stumpel DJ; van Roon E; de Boer J; Williams O; Pieters R; Stam RW
PLoS One; 2015; 10(3):e0120326. PubMed ID: 25793396
[TBL] [Abstract][Full Text] [Related]
17. Function of leukemogenic mixed lineage leukemia 1 (MLL) fusion proteins through distinct partner protein complexes.
Biswas D; Milne TA; Basrur V; Kim J; Elenitoba-Johnson KS; Allis CD; Roeder RG
Proc Natl Acad Sci U S A; 2011 Sep; 108(38):15751-6. PubMed ID: 21896721
[TBL] [Abstract][Full Text] [Related]
18. MiR-27a downregulates 14-3-3θ, RUNX1, AF4, and MLL-AF4, crucial drivers of blast transformation in t(4;11) leukemia cells.
Fioretti T; Zanobio M; Raia M; Errichiello S; Izzo B; Cattaneo F; Ammendola R; Cevenini A; Esposito G
Cell Biochem Funct; 2022 Oct; 40(7):706-717. PubMed ID: 35981137
[TBL] [Abstract][Full Text] [Related]
19. Down-regulation of DLX3 expression in MLL-AF4 childhood lymphoblastic leukemias is mediated by promoter region hypermethylation.
Campo Dell'Orto M; Banelli B; Giarin E; Accordi B; Trentin L; Romani M; te Kronnie G; Basso G
Oncol Rep; 2007 Aug; 18(2):417-23. PubMed ID: 17611665
[TBL] [Abstract][Full Text] [Related]
20. The AF4.MLL fusion protein is capable of inducing ALL in mice without requirement of MLL.AF4.
Bursen A; Schwabe K; Rüster B; Henschler R; Ruthardt M; Dingermann T; Marschalek R
Blood; 2010 Apr; 115(17):3570-9. PubMed ID: 20194896
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
