BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

186 related articles for article (PubMed ID: 37640864)

  • 1. Excited-state observation of active K-Ras reveals differential structural dynamics of wild-type versus oncogenic G12D and G12C mutants.
    Hansen AL; Xiang X; Yuan C; Bruschweiler-Li L; Brüschweiler R
    Nat Struct Mol Biol; 2023 Oct; 30(10):1446-1455. PubMed ID: 37640864
    [TBL] [Abstract][Full Text] [Related]  

  • 2.
    Pálfy G; Vida I; Perczel A
    Biomol NMR Assign; 2020 Apr; 14(1):1-7. PubMed ID: 31468366
    [TBL] [Abstract][Full Text] [Related]  

  • 3. NMR
    Yuan C; Hansen AL; Bruschweiler-Li L; Brüschweiler R
    Biomol NMR Assign; 2024 Jun; 18(1):7-13. PubMed ID: 37948018
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Conformational Dynamics Allows Sampling of an "Active-like" State by Oncogenic K-Ras-GDP.
    Grudzien P; Jang H; Leschinsky N; Nussinov R; Gaponenko V
    J Mol Biol; 2022 Sep; 434(17):167695. PubMed ID: 35752212
    [TBL] [Abstract][Full Text] [Related]  

  • 5. NMR
    Sharma AK; Lee SJ; Zhou M; Rigby AC; Townson SA
    Biomol NMR Assign; 2019 Apr; 13(1):227-231. PubMed ID: 30798456
    [TBL] [Abstract][Full Text] [Related]  

  • 6. In situ selectivity profiling and crystal structure of SML-8-73-1, an active site inhibitor of oncogenic K-Ras G12C.
    Hunter JC; Gurbani D; Ficarro SB; Carrasco MA; Lim SM; Choi HG; Xie T; Marto JA; Chen Z; Gray NS; Westover KD
    Proc Natl Acad Sci U S A; 2014 Jun; 111(24):8895-900. PubMed ID: 24889603
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Revealing the mechanism of action of a first-in-class covalent inhibitor of KRASG12C (ON) and other functional properties of oncogenic KRAS by
    Sharma AK; Pei J; Yang Y; Dyba M; Smith B; Rabara D; Larsen EK; Lightstone FC; Esposito D; Stephen AG; Wang B; Beltran PJ; Wallace E; Nissley DV; McCormick F; Maciag AE
    J Biol Chem; 2024 Feb; 300(2):105650. PubMed ID: 38237681
    [TBL] [Abstract][Full Text] [Related]  

  • 8. K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions.
    Ostrem JM; Peters U; Sos ML; Wells JA; Shokat KM
    Nature; 2013 Nov; 503(7477):548-51. PubMed ID: 24256730
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Solid-state 31P NMR spectroscopy of microcrystals of the Ras protein and its effector loop mutants: comparison between crystalline and solution state.
    Iuga A; Spoerner M; Kalbitzer HR; Brunner E
    J Mol Biol; 2004 Sep; 342(3):1033-40. PubMed ID: 15342254
    [TBL] [Abstract][Full Text] [Related]  

  • 10. An NMR comparison of the changes produced by different guanosine 5'-triphosphate analogs in wild-type and oncogenic mutant p21ras.
    Miller AF; Halkides CJ; Redfield AG
    Biochemistry; 1993 Jul; 32(29):7367-76. PubMed ID: 8338834
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The structural basis for the transition from Ras-GTP to Ras-GDP.
    Hall BE; Bar-Sagi D; Nassar N
    Proc Natl Acad Sci U S A; 2002 Sep; 99(19):12138-42. PubMed ID: 12213964
    [TBL] [Abstract][Full Text] [Related]  

  • 12. NMR
    Sharma AK; Lee SJ; Rigby AC; Townson SA
    Biomol NMR Assign; 2018 Oct; 12(2):269-272. PubMed ID: 29721757
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Ras Binder Induces a Modified Switch-II Pocket in GTP and GDP States.
    Gentile DR; Rathinaswamy MK; Jenkins ML; Moss SM; Siempelkamp BD; Renslo AR; Burke JE; Shokat KM
    Cell Chem Biol; 2017 Dec; 24(12):1455-1466.e14. PubMed ID: 29033317
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Distinct dynamics and interaction patterns in H- and K-Ras oncogenic P-loop mutants.
    Sayyed-Ahmad A; Prakash P; Gorfe AA
    Proteins; 2017 Sep; 85(9):1618-1632. PubMed ID: 28498561
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Guanosine triphosphatase stimulation of oncogenic Ras mutants.
    Ahmadian MR; Zor T; Vogt D; Kabsch W; Selinger Z; Wittinghofer A; Scheffzek K
    Proc Natl Acad Sci U S A; 1999 Jun; 96(12):7065-70. PubMed ID: 10359839
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The distinct conformational dynamics of K-Ras and H-Ras A59G.
    Lukman S; Grant BJ; Gorfe AA; Grant GH; McCammon JA
    PLoS Comput Biol; 2010 Sep; 6(9):. PubMed ID: 20838576
    [TBL] [Abstract][Full Text] [Related]  

  • 17. High-frequency 94 GHz ENDOR characterization of the metal binding site in wild-type Ras x GDP and its oncogenic mutant G12V in frozen solution.
    Bennati M; Hertel MM; Fritscher J; Prisner TF; Weiden N; Hofweber R; Spörner M; Horn G; Kalbitzer HR
    Biochemistry; 2006 Jan; 45(1):42-50. PubMed ID: 16388579
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The Importance of Mg
    Pálfy G; Menyhárd DK; Ákontz-Kiss H; Vida I; Batta G; Tőke O; Perczel A
    Chemistry; 2022 Oct; 28(59):e202201449. PubMed ID: 35781716
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The Ras-RasGAP complex: structural basis for GTPase activation and its loss in oncogenic Ras mutants.
    Scheffzek K; Ahmadian MR; Kabsch W; Wiesmüller L; Lautwein A; Schmitz F; Wittinghofer A
    Science; 1997 Jul; 277(5324):333-8. PubMed ID: 9219684
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mechanism of the guanine nucleotide exchange reaction of Ras GTPase--evidence for a GTP/GDP displacement model.
    Zhang B; Zhang Y; Shacter E; Zheng Y
    Biochemistry; 2005 Feb; 44(7):2566-76. PubMed ID: 15709769
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.