166 related articles for article (PubMed ID: 37642646)
1. Predicting and Interpreting Protein Developability Via Transfer of Convolutional Sequence Representation.
Golinski AW; Schmitz ZD; Nielsen GH; Johnson B; Saha D; Appiah S; Hackel BJ; Martiniani S
ACS Synth Biol; 2023 Sep; 12(9):2600-2615. PubMed ID: 37642646
[TBL] [Abstract][Full Text] [Related]
2. High-throughput developability assays enable library-scale identification of producible protein scaffold variants.
Golinski AW; Mischler KM; Laxminarayan S; Neurock NL; Fossing M; Pichman H; Martiniani S; Hackel BJ
Proc Natl Acad Sci U S A; 2021 Jun; 118(23):. PubMed ID: 34078670
[TBL] [Abstract][Full Text] [Related]
3. Sequence-developability mapping of affibody and fibronectin paratopes via library-scale variant characterization.
Nielsen GH; Schmitz ZD; Hackel BJ
Protein Eng Des Sel; 2024 Jan; 37():. PubMed ID: 38836499
[TBL] [Abstract][Full Text] [Related]
4. Assessment of Therapeutic Antibody Developability by Combinations of In Vitro and In Silico Methods.
Wolf Pérez AM; Lorenzen N; Vendruscolo M; Sormanni P
Methods Mol Biol; 2022; 2313():57-113. PubMed ID: 34478132
[TBL] [Abstract][Full Text] [Related]
5. Determinants of Developability and Evolvability of Synthetic Miniproteins as Ligand Scaffolds.
McConnell A; Batten SL; Hackel BJ
J Mol Biol; 2023 Dec; 435(24):168339. PubMed ID: 37923119
[TBL] [Abstract][Full Text] [Related]
6. Learning the local landscape of protein structures with convolutional neural networks.
Kulikova AV; Diaz DJ; Loy JM; Ellington AD; Wilke CO
J Biol Phys; 2021 Dec; 47(4):435-454. PubMed ID: 34751854
[TBL] [Abstract][Full Text] [Related]
7. The Therapeutic Antibody Profiler for Computational Developability Assessment.
Raybould MIJ; Deane CM
Methods Mol Biol; 2022; 2313():115-125. PubMed ID: 34478133
[TBL] [Abstract][Full Text] [Related]
8. In vitro and in silico assessment of the developability of a designed monoclonal antibody library.
Wolf Pérez AM; Sormanni P; Andersen JS; Sakhnini LI; Rodriguez-Leon I; Bjelke JR; Gajhede AJ; De Maria L; Otzen DE; Vendruscolo M; Lorenzen N
MAbs; 2019; 11(2):388-400. PubMed ID: 30523762
[TBL] [Abstract][Full Text] [Related]
9. Protein engineering via sequence-performance mapping.
McConnell A; Hackel BJ
Cell Syst; 2023 Aug; 14(8):656-666. PubMed ID: 37494931
[TBL] [Abstract][Full Text] [Related]
10. Predicting Antibody Developability Profiles Through Early Stage Discovery Screening.
Bailly M; Mieczkowski C; Juan V; Metwally E; Tomazela D; Baker J; Uchida M; Kofman E; Raoufi F; Motlagh S; Yu Y; Park J; Raghava S; Welsh J; Rauscher M; Raghunathan G; Hsieh M; Chen YL; Nguyen HT; Nguyen N; Cipriano D; Fayadat-Dilman L
MAbs; 2020; 12(1):1743053. PubMed ID: 32249670
[TBL] [Abstract][Full Text] [Related]
11. Pragmatic mAb lead molecule engineering from a developability perspective.
Chi B; De Oliveira G; Gallagher T; Mitchell L; Knightley L; Gonzalez CC; Russell S; Germaschewski V; Pearce C; Sellick CA
Biotechnol Bioeng; 2021 Oct; 118(10):3733-3743. PubMed ID: 33913507
[TBL] [Abstract][Full Text] [Related]
12. SeqPredNN: a neural network that generates protein sequences that fold into specified tertiary structures.
Lategan FA; Schreiber C; Patterton HG
BMC Bioinformatics; 2023 Oct; 24(1):373. PubMed ID: 37789284
[TBL] [Abstract][Full Text] [Related]
13. Super High-Throughput Screening of Enzyme Variants by Spectral Graph Convolutional Neural Networks.
Ramírez-Palacios C; Marrink SJ
J Chem Theory Comput; 2023 Jul; 19(14):4668-4677. PubMed ID: 36961994
[TBL] [Abstract][Full Text] [Related]
14. Current advances in biopharmaceutical informatics: guidelines, impact and challenges in the computational developability assessment of antibody therapeutics.
Khetan R; Curtis R; Deane CM; Hadsund JT; Kar U; Krawczyk K; Kuroda D; Robinson SA; Sormanni P; Tsumoto K; Warwicker J; Martin ACR
MAbs; 2022; 14(1):2020082. PubMed ID: 35104168
[TBL] [Abstract][Full Text] [Related]
15. Developability assessment at early-stage discovery to enable development of antibody-derived therapeutics.
Zhang W; Wang H; Feng N; Li Y; Gu J; Wang Z
Antib Ther; 2023 Jan; 6(1):13-29. PubMed ID: 36683767
[TBL] [Abstract][Full Text] [Related]
16. Development of a high yielding expression platform for the introduction of non-natural amino acids in protein sequences.
Roy G; Reier J; Garcia A; Martin T; Rice M; Wang J; Prophet M; Christie R; Dall'Acqua W; Ahuja S; Bowen MA; Marelli M
MAbs; 2020; 12(1):1684749. PubMed ID: 31775561
[TBL] [Abstract][Full Text] [Related]
17. An accelerated surface-mediated stress assay of antibody instability for developability studies.
Kopp MRG; Wolf Pérez AM; Zucca MV; Capasso Palmiero U; Friedrichsen B; Lorenzen N; Arosio P
MAbs; 2020; 12(1):1815995. PubMed ID: 32954930
[TBL] [Abstract][Full Text] [Related]
18. Five computational developability guidelines for therapeutic antibody profiling.
Raybould MIJ; Marks C; Krawczyk K; Taddese B; Nowak J; Lewis AP; Bujotzek A; Shi J; Deane CM
Proc Natl Acad Sci U S A; 2019 Mar; 116(10):4025-4030. PubMed ID: 30765520
[TBL] [Abstract][Full Text] [Related]
19. Improving the Developability of an Antigen Binding Fragment by Aspartate Substitutions.
Sakhnini LI; Greisen PJ; Wiberg C; Bozoky Z; Lund S; Wolf Perez AM; Karkov HS; Huus K; Hansen JJ; Bülow L; Lorenzen N; Dainiak MB; Pedersen AK
Biochemistry; 2019 Jun; 58(24):2750-2759. PubMed ID: 31117388
[TBL] [Abstract][Full Text] [Related]
20. PyPEF-An Integrated Framework for Data-Driven Protein Engineering.
Siedhoff NE; Illig AM; Schwaneberg U; Davari MD
J Chem Inf Model; 2021 Jul; 61(7):3463-3476. PubMed ID: 34260225
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]