These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

159 related articles for article (PubMed ID: 37676771)

  • 1. SARS-CoV-2 variants with NSP12 P323L/G671S mutations display enhanced virus replication in ferret upper airways and higher transmissibility.
    Kim SM; Kim EH; Casel MAB; Kim YI; Sun R; Kwak MJ; Yoo JS; Yu M; Yu KM; Jang SG; Rollon R; Choi JH; Gil J; Eun K; Kim H; Ensser A; Hwang J; Song MS; Kim MH; Jung JU; Choi YK
    Cell Rep; 2023 Sep; 42(9):113077. PubMed ID: 37676771
    [TBL] [Abstract][Full Text] [Related]  

  • 2. SARS-CoV-2 variants show temperature-dependent enhanced polymerase activity in the upper respiratory tract and high transmissibility.
    Kim SM; Kim EH; Casel MAB; Kim YI; Sun R; Kwack MJ; Yoo JS; Yu MA; Yu KM; Jang SG; Rollon R; Choi JH; Gil J; Eun K; Kim H; Ensser A; Hwang J; Song MS; Kim MH; Jung JU; Choi YK
    bioRxiv; 2022 Sep; ():. PubMed ID: 36203545
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Biochemical characterization of naturally occurring mutations in SARS-CoV-2 RNA-dependent RNA polymerase.
    Danda M; Klimešová A; Kušková K; Dostálková A; Pagáčová A; Prchal J; Kapisheva M; Ruml T; Rumlová M
    Protein Sci; 2024 Sep; 33(9):e5103. PubMed ID: 39145418
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Point mutations at specific sites of the nsp12-nsp8 interface dramatically affect the RNA polymerization activity of SARS-CoV-2.
    Ferrer-Orta C; Vázquez-Monteagudo S; Ferrero DS; Martínez-González B; Perales C; Domingo E; Verdaguer N
    Proc Natl Acad Sci U S A; 2024 Jul; 121(29):e2317977121. PubMed ID: 38990941
    [TBL] [Abstract][Full Text] [Related]  

  • 5. In silico analysis of non-structural protein 12 sequences from SARS-COV-2 found in Manaus, Amazonas, Brazil, reveals mutations linked to higher transmissibility.
    Zanchi FB; Ferreira GEM; Mariúba LAM; Glória JC; Nascimento VAD; Souza VC; Corado ALG; Nascimento FOD; Costa ÁKAD; Duarte DCG; Silva GAVD; Mejía MDCC; Pessoa KP; Gonçalves LMF; Brandão MJP; Jesus MS; Silva MSD; Costa CFD; Naveca FG
    An Acad Bras Cienc; 2024; 96(2):e20231336. PubMed ID: 38747801
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Genetic conservation of SARS-CoV-2 RNA replication complex in globally circulating isolates and recently emerged variants from humans and minks suggests minimal pre-existing resistance to remdesivir.
    Martin R; Li J; Parvangada A; Perry J; Cihlar T; Mo H; Porter D; Svarovskaia E
    Antiviral Res; 2021 Apr; 188():105033. PubMed ID: 33549572
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Remdesivir MD Simulations Suggest a More Favourable Binding to SARS-CoV-2 RNA Dependent RNA Polymerase Mutant P323L Than Wild-Type.
    Mohammad A; Al-Mulla F; Wei DQ; Abubaker J
    Biomolecules; 2021 Jun; 11(7):. PubMed ID: 34206274
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Analysis of the SARS-CoV-2 nsp12 P323L/A529V mutations: coeffect in the transiently peaking lineage C.36.3 on protein structure and response to treatment in Egyptian records.
    Abd-Elshafy DN; Nadeem R; Nasraa MH; Bahgat MM
    Z Naturforsch C J Biosci; 2024 Jan; 79(1-2):13-24. PubMed ID: 38265042
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Two conserved oligomer interfaces of NSP7 and NSP8 underpin the dynamic assembly of SARS-CoV-2 RdRP.
    Biswal M; Diggs S; Xu D; Khudaverdyan N; Lu J; Fang J; Blaha G; Hai R; Song J
    Nucleic Acids Res; 2021 Jun; 49(10):5956-5966. PubMed ID: 33999154
    [TBL] [Abstract][Full Text] [Related]  

  • 10. SARS-CoV-2 NSP12 associates with TRiC and the P323L substitution acts as a host adaption.
    Alruwaili M; Armstrong S; Prince T; Erdmann M; Matthews DA; Luu L; Davidson A; Aljabr W; Hiscox JA
    J Virol; 2023 Nov; 97(11):e0042423. PubMed ID: 37929963
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mutations in SARS-CoV-2 nsp7 and nsp8 proteins and their predicted impact on replication/transcription complex structure.
    Reshamwala SMS; Likhite V; Degani MS; Deb SS; Noronha SB
    J Med Virol; 2021 Jul; 93(7):4616-4619. PubMed ID: 33433004
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Binding properties of selective inhibitors of P323L mutated RdRp of SARS-CoV-2: a combined molecular screening, docking and dynamics simulation study.
    Chinnamadhu A; Ramakrishnan J; Suresh S; Poomani K
    J Biomol Struct Dyn; 2024 May; 42(8):4283-4296. PubMed ID: 37301607
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The P323L substitution in the SARS-CoV-2 polymerase (NSP12) confers a selective advantage during infection.
    Goldswain H; Dong X; Penrice-Randal R; Alruwaili M; Shawli GT; Prince T; Williamson MK; Raghwani J; Randle N; Jones B; Donovan-Banfield I; Salguero FJ; Tree JA; Hall Y; Hartley C; Erdmann M; Bazire J; Jearanaiwitayakul T; Semple MG; Openshaw PJM; Baillie JK; ; Emmett SR; Digard P; Matthews DA; Turtle L; Darby AC; Davidson AD; Carroll MW; Hiscox JA
    Genome Biol; 2023 Mar; 24(1):47. PubMed ID: 36915185
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Genomic characterization of SARS-CoV-2 isolates from patients in Turkey reveals the presence of novel mutations in spike and nsp12 proteins.
    Sahin E; Bozdayi G; Yigit S; Muftah H; Dizbay M; Tunccan OG; Fidan I; Caglar K
    J Med Virol; 2021 Oct; 93(10):6016-6026. PubMed ID: 34241906
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Effects of natural polymorphisms in SARS-CoV-2 RNA-dependent RNA polymerase on its activity and sensitivity to inhibitors in vitro.
    Miropolskaya N; Kozlov M; Petushkov I; Prostova M; Pupov D; Esyunina D; Kochetkov S; Kulbachinskiy A
    Biochimie; 2023 Mar; 206():81-88. PubMed ID: 36252889
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Geographical distribution of SARS-CoV-2 amino acids mutations and the concomitant evolution of seven distinct clades in non-human hosts.
    Magateshvaren Saras MA; Patro LPP; Uttamrao PP; Rathinavelan T
    Zoonoses Public Health; 2022 Nov; 69(7):816-825. PubMed ID: 35614572
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Global variation in SARS-CoV-2 proteome and its implication in pre-lockdown emergence and dissemination of 5 dominant SARS-CoV-2 clades.
    Patro LPP; Sathyaseelan C; Uttamrao PP; Rathinavelan T
    Infect Genet Evol; 2021 Sep; 93():104973. PubMed ID: 34147651
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Biochemical simulation of mutation synthesis and repair during SARS-CoV-2 RNA polymerization.
    Oo A; Chen Z; Cao D; Cho YJ; Liang B; Schinazi RF; Kim B
    Virology; 2024 Dec; 600():110255. PubMed ID: 39366027
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Optimized Recombinant Expression and Purification of the SARS-CoV-2 Polymerase Complex.
    Podadera A; Campo L; Rehman F; Kolobaric N; Zutic A; Ng KK
    Curr Protoc; 2024 Mar; 4(3):e1007. PubMed ID: 38511495
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Targeting SARS-CoV-2 Nsp12/Nsp8 interaction interface with approved and investigational drugs: an
    Mutlu O; Ugurel OM; Sariyer E; Ata O; Inci TG; Ugurel E; Kocer S; Turgut-Balik D
    J Biomol Struct Dyn; 2022 Feb; 40(2):918-930. PubMed ID: 32933378
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.