174 related articles for article (PubMed ID: 37681413)
1. Mocetinostat activates Krüppel-like factor 4 and protects against tissue destruction and inflammation in osteoarthritis.
Kawata M; McClatchy DB; Diedrich JK; Olmer M; Johnson KA; Yates JR; Lotz MK
JCI Insight; 2023 Sep; 8(17):. PubMed ID: 37681413
[TBL] [Abstract][Full Text] [Related]
2. Krüppel-like factor-4 and Krüppel-like factor-2 are important regulators of joint tissue cells and protect against tissue destruction and inflammation in osteoarthritis.
Kawata M; Teramura T; Ordoukhanian P; Head SR; Natarajan P; Sundaresan A; Olmer M; Asahara H; Lotz MK
Ann Rheum Dis; 2022 May; ():. PubMed ID: 35534137
[TBL] [Abstract][Full Text] [Related]
3. Histone deacetylase inhibition activates Nrf2 and protects against osteoarthritis.
Cai D; Yin S; Yang J; Jiang Q; Cao W
Arthritis Res Ther; 2015 Sep; 17():269. PubMed ID: 26408027
[TBL] [Abstract][Full Text] [Related]
4. Isoform-Selective HDAC Inhibitor Mocetinostat (MGCD0103) Alleviates Myocardial Ischemia/Reperfusion Injury Via Mitochondrial Protection Through the HDACs/CREB/PGC-1α Signaling Pathway.
Wang K; Tang R; Wang S; Xiong Y; Wang W; Chen G; Zhang K; Li P; Tang YD
J Cardiovasc Pharmacol; 2022 Feb; 79(2):217-228. PubMed ID: 34983914
[TBL] [Abstract][Full Text] [Related]
5. 2 dyn/cm
Chang SF; Huang KC; Chang HI; Lee KC; Su YP; Chen CN
J Cell Physiol; 2018 Jan; 234(1):958-968. PubMed ID: 30132856
[TBL] [Abstract][Full Text] [Related]
6. KLF4, negatively regulated by miR-7, suppresses osteoarthritis development via activating TGF-β1 signaling.
Li J; Jiang M; Xiong C; Pan J; Jia S; Zhang Y; Zhang J; Xu N; Zhou X; Huang Y
Int Immunopharmacol; 2022 Jan; 102():108416. PubMed ID: 34891002
[TBL] [Abstract][Full Text] [Related]
7. Inhibition of HDAC6 by Tubastatin A reduces chondrocyte oxidative stress in chondrocytes and ameliorates mouse osteoarthritis by activating autophagy.
Shen Z; Ji K; Cai Z; Huang C; He X; Xu H; Chen G
Aging (Albany NY); 2021 Mar; 13(7):9820-9837. PubMed ID: 33744850
[TBL] [Abstract][Full Text] [Related]
8. Krüppel-like factor 15 deficiency exacerbates osteoarthritis through reduced expression of peroxisome proliferator-activated receptor gamma signaling in mice.
Ikuta K; Hayashi S; Kikuchi K; Fujita M; Anjiki K; Onoi Y; Tachibana S; Suda Y; Wada K; Kuroda Y; Nakano N; Maeda T; Matsumoto T; Hosooka T; Ogawa W; Kuroda R
Osteoarthritis Cartilage; 2024 Jan; 32(1):28-40. PubMed ID: 37648149
[TBL] [Abstract][Full Text] [Related]
9. Anti-Fibrotic Effects of Class I HDAC Inhibitor, Mocetinostat Is Associated with IL-6/Stat3 Signaling in Ischemic Heart Failure.
Nural-Guvener H; Zakharova L; Feehery L; Sljukic S; Gaballa M
Int J Mol Sci; 2015 May; 16(5):11482-99. PubMed ID: 25997003
[TBL] [Abstract][Full Text] [Related]
10. Overexpression of secretory leukocyte peptidase inhibitor (SLPI) does not modulate experimental osteoarthritis but may be a biomarker for the disease.
Kim HE; Shin Y; Jung IJ; Yang JI; Chun CH; Kim HA; Chun JS
Osteoarthritis Cartilage; 2021 Apr; 29(4):558-567. PubMed ID: 33485930
[TBL] [Abstract][Full Text] [Related]
11. Histone Deacetylase Inhibitor Vorinostat (SAHA) Suppresses IL-1β-Induced Matrix Metallopeptidase-13 Expression by Inhibiting IL-6 in Osteoarthritis Chondrocyte.
Makki MS; Haqqi TM
Am J Pathol; 2016 Oct; 186(10):2701-8. PubMed ID: 27555113
[TBL] [Abstract][Full Text] [Related]
12. Neural EGFL like 1 as a potential pro-chondrogenic, anti-inflammatory dual-functional disease-modifying osteoarthritis drug.
Li C; Zheng Z; Ha P; Jiang W; Berthiaume EA; Lee S; Mills Z; Pan H; Chen EC; Jiang J; Culiat CT; Zhang X; Ting K; Soo C
Biomaterials; 2020 Jan; 226():119541. PubMed ID: 31634652
[TBL] [Abstract][Full Text] [Related]
13. 14-3-3 epsilon is an intracellular component of TNFR2 receptor complex and its activation protects against osteoarthritis.
Fu W; Hettinghouse A; Chen Y; Hu W; Ding X; Chen M; Ding Y; Mundra J; Song W; Liu R; Yi YS; Attur M; Samuels J; Strauss E; Leucht P; Schwarzkopf R; Liu CJ
Ann Rheum Dis; 2021 Dec; 80(12):1615-1627. PubMed ID: 34226187
[TBL] [Abstract][Full Text] [Related]
14. A phase 2 study of mocetinostat, a histone deacetylase inhibitor, in relapsed or refractory lymphoma.
Batlevi CL; Crump M; Andreadis C; Rizzieri D; Assouline SE; Fox S; van der Jagt RHC; Copeland A; Potvin D; Chao R; Younes A
Br J Haematol; 2017 Aug; 178(3):434-441. PubMed ID: 28440559
[TBL] [Abstract][Full Text] [Related]
15. Cryptotanshinone protects against IL-1β-induced inflammation in human osteoarthritis chondrocytes and ameliorates the progression of osteoarthritis in mice.
Feng Z; Zheng W; Li X; Lin J; Xie C; Li H; Cheng L; Wu A; Ni W
Int Immunopharmacol; 2017 Sep; 50():161-167. PubMed ID: 28666239
[TBL] [Abstract][Full Text] [Related]
16. Mocetinostat for patients with previously treated, locally advanced/metastatic urothelial carcinoma and inactivating alterations of acetyltransferase genes.
Grivas P; Mortazavi A; Picus J; Hahn NM; Milowsky MI; Hart LL; Alva A; Bellmunt J; Pal SK; Bambury RM; O'Donnell PH; Gupta S; Guancial EA; Sonpavde GP; Faltaos D; Potvin D; Christensen JG; Chao RC; Rosenberg JE
Cancer; 2019 Feb; 125(4):533-540. PubMed ID: 30570744
[TBL] [Abstract][Full Text] [Related]
17. Epigenetics in osteoarthritis: Potential of HDAC inhibitors as therapeutics.
Khan NM; Haqqi TM
Pharmacol Res; 2018 Feb; 128():73-79. PubMed ID: 28827187
[TBL] [Abstract][Full Text] [Related]
18. Kartogenin inhibits pain behavior, chondrocyte inflammation, and attenuates osteoarthritis progression in mice through induction of IL-10.
Kwon JY; Lee SH; Na HS; Jung K; Choi J; Cho KH; Lee CY; Kim SJ; Park SH; Shin DY; Cho ML
Sci Rep; 2018 Sep; 8(1):13832. PubMed ID: 30218055
[TBL] [Abstract][Full Text] [Related]
19. Krüppel-like factor 4 mediates histone deacetylase inhibitor-induced prevention of cardiac hypertrophy.
Kee HJ; Kook H
J Mol Cell Cardiol; 2009 Dec; 47(6):770-80. PubMed ID: 19729022
[TBL] [Abstract][Full Text] [Related]
20. Chondroprotective Effects of a Histone Deacetylase Inhibitor, Panobinostat, on Pain Behavior and Cartilage Degradation in Anterior Cruciate Ligament Transection-Induced Experimental Osteoarthritic Rats.
Wen ZH; Huang JS; Lin YY; Yao ZK; Lai YC; Chen WF; Liu HT; Lin SC; Tsai YC; Tsai TC; Jean YH
Int J Mol Sci; 2021 Jul; 22(14):. PubMed ID: 34298911
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
